From what patients are prescribed Enterosept? Indications for use of this tool will be listed below. Also from this article you will learn about how to use the medication mentioned, what characteristics it has, whether it has side effects and prohibitions on prescribing.
Composition, description of the drug and its form
The medicine "Enterosept" - tablets, the instruction of which is enclosed in a paper bundle, coated with a yellow shell, having a round biconvex shape.
The active ingredient in this drug is nifuroxazide. In addition to it, the composition of the medication under consideration includes such auxiliary components as microcrystalline cellulose, sodium starch glycolate, polyvinylpyrrolidone and calcium stearate.
As for the tablet shell, it consists of transparent opadra II, polysorbate 80, polyvinyl alcohol, talc and polyethylene glycol.
Pharmacodynamic characteristics
What are Enterosept tablets? The instruction for use claims that this is an antimicrobial agent belonging to the group of 5-nitrofurans, and also related to intestinal antiseptics. This medication helps to block the activity of dehydrogenase, inhibition of the process of cellular respiration and the cycle of tricarboxylic acids. Also in microbial cells, it disrupts protein synthesis and reduces the production of toxins by harmful microorganisms.
Kinetic characteristics
Are Enterosept tablets absorbed? Instructions for use report that after oral administration, this medicine is not absorbed from the digestive system. It provides a high concentration of the active component in the intestine, and after some time it is excreted along with feces.
The rate of excretion of the drug in question depends on the dosage taken, as well as the motility of the digestive tract.
Enterosept tablets: what is prescribed?
Indications for the use of this tool are the following pathological conditions:
- Acute and chronic diarrhea caused by gram-positive intestinal bacteria.
- Acute and chronic diarrhea caused by certain gram-negative bacteria.
Drug prescribing bans
“Enterosept” is a medicine for diarrhea in adults (children are prescribed it after 6 years). It is forbidden to use when:
- high sensitivity to drug substances;
- an allergic reaction to 5-nitrofuran derivatives ;
- in children under six years old.
Enterosept tablets: instructions for use
Enterosept antidiarrheal agent is prescribed only inside. A tablet for oral administration should be swallowed in its entirety, without crushing and chewing, with a half glass of water.
For children from six years old, as well as adults, this medication is prescribed two tablets four times a day. The drug is taken regardless of the meal at regular intervals (for example, every 6 hours).
In the treatment of acute diarrhea, the drug in question is recommended to be taken within three days. If after such treatment the symptoms do not disappear, then you should consult a doctor.
The course of therapy for other diseases, which also occur with diarrhea, is no more than one week.
Side effects
The considered medicine for diarrhea in adults and in children can cause the following reactions of a negative nature:
- From the digestive system: with individual sensitivity to nifuroxazide, the patient may experience abdominal pain, exacerbation of diarrhea, and nausea. If such signs of low intensity occur, there is no need to use special therapy, as well as stop taking the medicine. With the development of these symptoms of significant intensity, it is advisable to stop taking the medication. In a subsequent patient, nitrofuran derivatives are not recommended.
- From the lymphatic and hematopoietic systems: the instructions describe the occurrence of granulocytopenia.
- From the subcutaneous tissue and skin: skin reactions in the form of a rash can very rarely develop.
It cannot be said that nifuroxazide is usually well tolerated by patients. Adverse reactions with its intake are extremely rare.
If you have negative effects that are not indicated in the instructions, then you should inform your doctor about this.
Overdose and interaction
Can there be symptoms of an overdose when taking a drug such as Enterosept? The instruction for use does not contain any information in this regard. In case of an overdose with this drug, it is recommended to wash the stomach, and also prescribe symptomatic treatment.
Due to the strong adsorption properties of the drug, it is necessary to avoid its simultaneous administration with other oral agents.
Special information
During the treatment with Enterosept, it is forbidden to drink alcoholic beverages, since they increase the body's sensitivity to the medication in question and can provoke the development of a disulfiram-like effect, which is manifested by exacerbation of diarrhea, abdominal pain, vomiting, skin hyperemia, shortness of breath, sensation of heat in the upper body and in the face, a feeling of fear and tachycardia.
If during treatment with this agent the patient has symptoms of dehydration, then parenteral or oral rehydration therapy is necessary (depending on the clinical condition of the person).
If hypersensitivity reactions such as shortness of breath, itching, and skin rash occur, you must stop taking the medicine.
Nifuroxazide should not be used for more than one week. If diarrhea lasts more than 3 days from the start of treatment, then an in-depth diagnosis is necessary to identify the causes of this pathology.
The medication in question is not used as monotherapy to eliminate intestinal infections that are complicated by septicemia. In severe invasive diarrhea, an antibiotic is necessary, since nifuroxazide is not absorbed from the gastrointestinal tract.
During treatment with Enterosept, it is advisable to adhere to a diet, exclude juices, fresh fruits, vegetables, as well as dishes difficult for digestion from your diet.
Reviews
What do consumers say about Enterosept? Reviews report that this remedy manifests itself as a highly effective antidiarrheal drug. Its use contributes to the complete elimination of diarrhea, which prevents dehydration of the body.
The disadvantages of this tool include the impossibility of its use by children under six years of age.