"Dazolik" is a drug with an antiprotozoal effect and enhanced antibacterial action.
The medication is highly effective in eliminating germs that can occur and multiply without oxygen. According to the instructions and reviews about "Dazolik", the drug helps to eliminate giardiasis, demodicosis, trichomoniasis. The drug is in the form of capsules for oral administration. Each tablet is film-coated, the capsules have a milky tint. The drug is packaged in blisters of ten pieces, which are placed in a cardboard box.
Chemical composition
The main active substance of the drug is ornidazole. In one capsule it contains five hundred milligrams. As additional trace elements of the drug are:
- Starch.
- Polyvinylpyrrolidone.
- Purified Talc.
- Microcrystalline cellulose.
- Titanium dioxide.
- Ethylene glycol polymer.
- Pyrogenic silicon dioxide.
Reviews on the composition of "Dazolik" are rare. Basically, patients pay attention to the positive and negative effects of the drug. Only a few respondents note that the capsules of this product are easy to swallow. In this case, there is no discomfort.
pharmachologic effect
According to reviews, tablets "Dazolik" have a bright antibacterial and antiprotozoal effect in relation to Trichomonas, E. coli, Clostridia and anaerobic bacteria.
Having penetrated the patientโs body, the main microelement of the drug undergoes a series of certain reactions, after which it enters the pathogen cells in deoxyribonucleic acid, slowing down the process of connecting nucleic acids. This leads to the elimination of the malicious object.
Indications
The drug "Dazolik" can be used only after a full examination of the patient and the appointment of a doctor by the doctor. The main reasons for using this drug are the following conditions and diseases:
- Trichomoniasis (an infectious disease of the genitourinary system that is caused by vaginal trichomonas).
- Dysentery (an infectious disease characterized by general infectious intoxication syndrome and gastrointestinal tract syndrome, mainly the distal colon).
- Giardiasis (a common infectious disease of the human body caused by the intestinal unicellular parasite Giardia).
- For prophylaxis before carrying out operations on the pelvic organs, representatives of the beautiful half of humanity.
Contraindications
Before taking capsules, the patient needs to familiarize themselves with the instructions for use, since the medication has some prohibitions on taking:
- Individual intolerance to the main component.
- Diseases of the nervous system.
- Epilepsy (a neurological ailment, which manifests itself in the predisposition of the body to the sudden onset of convulsive attacks).
- Chronic alcoholism (a disease characterized by a pathological addiction to alcohol).
- Impaired liver function.
- Pregnancy.
Instructions for use
The tablets are intended for oral administration. The drug must be taken after a meal with a pill with water.
The daily dosage and duration of treatment is determined by the attending doctor, depending on the clinical indications, patient weight, age.
According to doctors, "Dazolik" is prescribed for adults in the presence of trichomoniasis. In this case, it is recommended to take one tablet three times a day orally in conjunction with the intravaginal use of the medicine, one tablet twice a day - in the morning and evening hours. The duration of the course, as a rule, does not exceed five to seven days.
When diagnosing dysentery, which can be triggered by amoeba, the dosage of the drug is calculated based on the patientโs weight. The duration of therapy should be at least three days.
In order to prevent the development of infections caused by the multiplication of anaerobic bacteria, it is recommended to use one capsule twice a day several days before surgery and for three days after surgery.
Drug treatment cannot last longer than ten days. If during this time the patient does not have improvements or the health condition worsens, you should immediately consult a doctor to clarify the diagnosis and adjust the therapy.
Can I use the drug during pregnancy?
It is strictly contraindicated to use the drug in the first months of pregnancy, since at this time the formation of organs in the fetus takes place, and there is no information on the effect of the active trace element on the development of the embryo.
Use "Dazolik" in the second and third trimester is possible only after assessing the likely danger to the fetus and the expected positive effect for the expectant mother. The therapy is under the supervision of the attending doctor. The minimum dosage is used. During treatment, the medical specialist must constantly monitor the general condition of the mother and the development of the fetus. If adverse effects occur, drug treatment should be stopped immediately.
The course of therapy "Dazolikom" with lactation is not carried out. If necessary, treatment with this medication, a woman needs to decide on the abolition of breastfeeding and the transfer of the baby to food with milk formula.
Adverse reactions
With proper observance of the doctor's prescriptions and a correctly calculated dose, the drug is remarkably tolerated by people. With increased sensitivity or an increase in standard dosage, the patient is likely to experience a number of negative phenomena:
- Migraine.
- Paresthesia (a disorder of sensitivity, which is characterized by spontaneously arising sensations of burning, tingling, crawling ants).
- Tremor (fast rhythmic movements of the limbs or trunk, caused by muscle contractions and associated with a temporary delay in corrective afferent signals).
- Neuropathy (a pathological condition in which there is a violation of the function of a particular nerve).
- The appearance of an unpleasant aftertaste in the oral cavity.
- Pain in the stomach.
- Itching
- Dermatitis of an allergic etiology, which is characterized by a sharp appearance of severely itchy blisters.
- Small rashes.
Overdose
When using high dosages of the drug or taking the drug for more than ten days, signs of an overdose may appear:
- Lack of coordination and perception of reality.
- Diseases of the liver and kidneys.
With the development of such symptoms, drug therapy should be discontinued and consult a doctor for help. The patient is washed with a stomach, then activated charcoal is given. If necessary, carry out complex treatment.
Interaction with other medicines
With the joint use of "Dazolik" with anticoagulants, it is possible to suppress the therapeutic effect of the latter.
When using tablets intravaginally with other local antiseptic agents, an increase in the effect of antiseptics is observed.
The drug should be used with extreme caution in conjunction with drugs that contain ethyl alcohol, since this interaction increases the likelihood of complications from the liver.
Features
According to reviews, "Dazolik" in gynecology can be used to eliminate trichomoniasis. In this case, both sexual partners must undergo treatment. During therapy, you need to refrain from intimate communication.
Analogs
There are many drugs that are similar in composition and therapeutic effect to Dazolik. The most popular of them:
- Ornisid.
- Guyro
- Avrazor
- Ornidazole
- "Ornidazole Vero".
- Tiberal.
Before using a similar drug, you should consult your doctor.
"Ornidazole"
it is a pharmacological drug that has an antiprotozoal and antibacterial effect. The mechanism of action of the drug is based on the ability to recover under the influence of microorganism strains, and then the creation of complex compounds with their deoxyribonucleic acid.
As a result, there is a violation of the process of renewal and translation of deoxyribonucleic acid. The metabolic products of the drug, also having cytotoxic activity, lead to the failure of the cellular respiration of bacteria.
When taken orally, the drug is remarkably absorbed in the digestive tract. The ability of the drug to be absorbed is ninety percent. Communication with blood proteins - no more than thirteen percent. The main active trace element reaches its maximum plasma content three hours after ingestion.
The medication has a good ability to get into all tissues and body fluids, as well as pass through the hematoplacental barrier. The active substance is metabolized in the liver, while forming metabolites that have antimicrobial and antiprotozoal effects.
About eighty-five percent of the total dosage taken is excreted within five days. Seventy percent of ornidazole is excreted by the kidneys in the urine, thirty percent - with feces (in unchanged form in the form of metabolites). The elimination half-life is from twelve to fourteen hours.
Storage conditions of the drug "Dazolik"
Tablets are dispensed at pharmacies according to the prescription of a medical specialist. The drug should be kept in a dark place away from children, at a temperature of no more than twenty-five degrees. The shelf life of the drug is three years. After this time, the drug must be discarded. The average price of the drug is 280-350 rubles per package. The shelf life of the drug is three years. This is indicated in the instructions for use.
Dazolik: reviews
The price of analogues is slightly higher, for example:
- Gayro - 450 rubles.
- Avrazor - 400 rubles.
- Tiberal - 690 rubles.
When comparing price and quality, patients are more likely to choose Dazolik.
Substitute drugs are used to eliminate infectious diseases.
As a rule, patients leave good reviews about Dazolik. People note its high therapeutic effectiveness and rapid improvement in well-being when using it.
Patients also note negative aspects when using the drug, for example, slight nausea, drowsiness after using Ornidazole and Dazolik. In the reviews, many patients narrate about the good tolerability of the drug.