In the article, we will consider whether they become fat from Duphaston. This pharmaceutical product belongs to the category of hormonal medicines containing progesterone in the hormone. This medicine is used in gynecological clinical practice for the treatment of various pathologies that are accompanied by hormonal disorders, for example, insufficient concentration of progesterone in the patient’s blood, menstrual irregularities, and normalization of pregnancy.
Many women are wondering if they are getting fat from Duphaston. The answer will be presented below.
Composition and form of release
This medication is made in the form of tablets for oral administration, white, rounded biconvex shape with beveled borders. On one side of the tablets there is a dividing risk. The main active element of the drug is didrogesterone, the content of which in 1 tablet is 10 mg. In addition, some of its ingredients include excipients, which include:
- hypromellose;
- colloidal silicon dioxide;
- lactose monohydrate;
- corn starch;
- titanium dioxide;
- magnesium stearate;
- polyethylene glycol.
The medicine is packaged in blisters for 20 and 28 tablets. A cardboard box contains one blister and an annotation on the use of the drug.
Will they be taken from Duphaston? About this will tell us the instruction.
Pharmacological properties
According to the chemical formula and clinical actions, the main active element, dydrogesterone, is similar to its own (endogenous) progesterone, which is synthesized in the female body. Therefore, when taken orally, this hormone has a similar biological effect. Due to the fact that dydrogesterone is not a derivative of testosterone (male sex hormones), it does not have androgenic (testosterone effect), estrogenic (clinical effect of estrogen), glucocorticoid (glucocorticoid effect) effects. Also, it does not affect the processes of carbohydrate metabolism in the body and does not change hemostasis indicators (blood coagulation).
After taking the drug Duphaston, the body temperature does not change. Dydrogesterone helps to stabilize the lipid profile of the blood (ratio and level of essential fats, including cholesterol). The active element of Dufaston tablets directly affects the condition of the endometrium (uterine mucosa) and prevents the development of its hypertrophy (pathological increase in size).
After oral administration of the drug, the active substance is absorbed from the intestinal lumen into the blood. It is distributed in the tissues and undergoes a metabolic process in the liver with the formation of decay products, which are excreted from the body through the kidneys with urine. The half-life of the substance (half the dose of the drug) is 18 hours.
Women are asked to receive a doctor’s answer to the question of whether they are getting fat from Duphaston.
Indications for appointment
The main indication for the use of a pharmacological drug is progesterone deficiency (a decrease in the concentration of endogenous progesterone in the body) in the following pathological conditions:
- infertility, which is due to the lack of functionality of the luteal phase of the menstrual cycle, the functioning of the corpus luteum (luteal insufficiency);
- endometriosis - the development of ectopic foci in endometrial cells outside the uterus;
- the threat of spontaneous miscarriage during pregnancy, due to the insufficient concentration of endogenous progesterone in the blood in the blood;
- premenstrual syndrome, which is accompanied by severe functional disorders in the body of a woman and soreness;
- dysmenorrhea (irregular menstruation in the reproductive age);
- the absence of menstruation of a secondary nature (amenorrhea), due to various pathologies of the organs of the reproductive system;
- uterine bleeding with the occurrence of functional disorders in the organs of the reproductive system.
In addition, this pharmacological drug is used in hormone replacement therapy in cases where it is necessary to neutralize the increased effects of estrogen on the endometrial layer of the uterus during the induced (after surgery) or natural postmenopause.
Are Dufaston connected with completeness? Let's figure it out.
Contraindications
An absolute contraindication to the use of the drug is intolerance to its active element or auxiliary substances. With caution, the medication is prescribed to women who have a history of allergic reactions.
Dosage and method of administration
Duphaston medication is prescribed to be taken orally, without chewing, washed down with water. Dosages and dosage regimen depend on the type of pathology:
- With endometriosis - 1 tablet 2 times a day from the 5th to the 25th day of the cycle.
- With the threat of termination of pregnancy - 40 mg once, after which 10 mg every 8 hours.
- Habitual miscarriage - 1 tablet in 2 divided doses per day until the 20th week of gestation, after which the dosage of the drug must be gradually reduced.
- Infertility due to insufficiency of the corpus luteum - 1 tablet 1 time per day from the 14th to the 25th day of the cycle.
- Premenstrual syndrome, amenorrhea - 1 tablet 2 times a day from the 11th to the 25th day.
- Dysmenorrhea - 1 tablet 2 times a day from the 5th to the 25th day of the cycle.
- Dysfunctional bleeding from the genital tract - to stop for 5-7 days, the pharmacological drug "Dufaston" is taken in a dosage of 10 mg 2 times a day, in order to prevent relapse - 10 mg 2 times a day from the 11th to the 25th day of the cycle .
During hormone replacement treatment (including amenorrhea therapy), this pharmacological drug is taken simultaneously with estrogens, 1 tablet 1 time per day from the 14th day. With the constant use of estrogen, the medication is taken in the same way.
Side effects
Whether “Dufaston” is stolen is not an idle question.
Taking a medication can lead to the development of some pathological reactions of the body, which include:
- Liver, digestive and hepatobiliary system - pain in the abdomen, impaired functionality of the gallbladder and liver, which manifest themselves in the form of general weakness, a feeling of heaviness in the right hypochondrium, minor jaundice.
- Nervous system - headaches that are pronounced paroxysmal in nature, resembling migraines.
- Red bone marrow and blood are hemolytic anemia, which is characterized by excessive destruction of red blood cells.
- The reproductive system is the development of uterine bleeding, which is stopped by increasing the dosage of the drug "Dufaston", increasing the sensitivity of the mammary glands.
- Allergic phenomena - characteristic skin changes in the form of a rash, itching. Sensitivity reactions of a general nature rarely occur - Quincke's edema and anaphylactic shock.
In case of side effects, taking the medication is recommended to stop or adjust its dosage.
Will they be taken from Duphaston? Specialist response
Many women are sure that weight gain has a direct relationship with hormonal medication. However, this is not always the case. Experts say that today only hormones are available that have low dosages of hormones, so they are not capable of causing obesity in women during treatment.
So, are they getting better from Dufaston or not?
If a woman begins to recover much while taking the drug, this indicates first of all that her appetite is increasing, and this is considered normal when the hormonal background is normalized. Gynecologists and nutritionists recommend that such patients adhere to the correct diet and dietary rules.
Reviews of women on completeness from Duphaston are presented below.
Special recommendations
Before starting treatment, it is important to read the instructions. In some cases, diffuse uterine bleeding may develop. If bleeding does not stop after increasing the dose of the drug, a further gynecological examination should be performed to determine the cause.
When combined with estrogen-containing agents, their side effects and contraindications should be considered.
Before starting hormone replacement treatment using the pharmacological drug “Duphaston”, a comprehensive examination is carried out with the identification of adverse reactions, features of the functionality of the organs of the reproductive and urinary system and other pathological processes, including in the anamnesis.
According to indications, it is possible to use the medication during pregnancy under the supervision of a specialist.
If necessary, the reception during lactation, the child should be transferred to an artificial milk mixture.
In the case of progesterone-dependent tumors (benign or malignant), it is important to conduct clinical studies of their response to the main component of this drug entering the body.
The drug is not recommended for patients with congenital, hereditary lactase deficiency.
Tablets do not affect the speed of mental and motor reactions, as well as the concentration of attention.
Consequences of taking
After treatment with this medication in women, the menstrual cycle stabilizes, the threat of miscarriage during pregnancy disappears, the condition during premenstrual syndrome stabilizes, and pathological uterine bleeding with menopause stops.
We reviewed the instructions for Dufaston. Will they stole from it? According to women, yes.
Doctors reviews
Specialists characterize the drug as a highly effective and versatile hormonal agent for a variety of pathologies of the female reproductive system. They recommend this medicine to many patients who have similar problems, however, to achieve the best result, according to doctors, it is necessary to correctly determine the exact dosages and days of the cycle on which to start taking the medicine. If these requirements are not met, the effectiveness of the drug will be low, moreover, it can cause some complications, for example, the development of bleeding.
Women's reviews
Many women complain that they are recovering from Dufaston. But this is most likely due to increased appetite. Patients claim that it is not difficult to control weight if you adhere to proper nutrition.