Betalok describes the instructions for use as a medicine related to the pharmacological group of beta1-blockers. The main active ingredient of this drug is metoprolol tartrate. It is produced by manufacturers in the form of tablets weighing 100 milligrams, which are packed in plastic bottles of 100 pieces each.
"Metoprolol" has pharmacological properties based on the ability of the drug to have a hypotensive and antianginal effect. The medicine effectively reduces heart rate, contractility and excitability of the myocardium, it helps to slow down the processes of AV conduction. The drug “Betalok” describes the instructions for use as a tool that helps to reduce cardiac output and the amount of oxygen consumed by the myocardium. "Metoprolol" has the ability to reduce the stimulating effects of catecholamines when exposed to the patient's heart during psychophysical stress. The medicine has a hypotensive effect, stabilizing after two weeks of administration. "Metoprolol" shows effectiveness in the treatment of a wide range of cardiovascular diseases, among which myocardial infarction, coronary heart disease, and arrhythmias of various types can be indicated; it is effective as a prophylactic in preventing recurrence of a heart attack.
The pharmacokinetic properties of the Betalok drug are described in the instructions for use in this way. After taking the drug, almost all of it is absorbed from the digestive tract in a short time, its maximum concentration in plasma is achieved within one to two hours. The drug is able to intensively metabolize in the tissues of the liver, while the resulting metabolites practically do not have activity in relation to any organs of the body. The half-life of the components of the drug is approximately three to four hours, and for the entire period of taking the drug is practically unchanged. Excretion of metoprolol is carried out mainly by the kidneys - more than 95% of the dose of the substance, while no more than three percent is excreted unchanged.
"Betalok" instruction recommends taking in cases of the following diseases: for the treatment of arterial hypertension, as a therapeutic agent is used to prevent angina attacks. The medicine is indicated in cases of cardiac arrhythmias, as well as for secondary prophylaxis, necessary after diseases of the cardiovascular system.
The dosage regimen of the drug "Betalok" instructions for use recommends to establish such. The average dose of the drug when taken twice is 100 milligrams per day. In some cases, the instruction stipulates the possibility of a gradual increase in the dose by half. If the drug is administered intravenously, then a single dose is from 2 to 5 mg. If in this case the desired effect is not achieved, the drug can be reintroduced after 5 minutes.
The dosage regimen should take into account that the maximum dose of the drug is 400 mg per day.
When taking Betalok tablets, they can cause side effects from various body systems. A detailed listing of them and a description of the symptoms is given in the instructions for use of the drug.
Contraindications to taking the medicine are various in type and nature of the course of the blockade of cardiovascular conduction, arterial hypotension, cardiogenic shock and other diseases. Reception is contraindicated if the patient has hypersensitivity to its components. You should not take the drug during pregnancy and during breastfeeding.
With extreme caution, you should approach the use of the drug in patients with COPD,
diabetes, Raynaud’s disease.
Discontinuation of the drug is recommended to be carried out gradually, this process should last at least ten days.
The drug has a number of special forms of action, when used together with other drugs. About this there is detailed information in the instructions for use.