The drug is available in whitish tablets or as a solution for injection.
Biconvex tablets, round in shape.
Structure:
Active substance
- Ethamsylate - 250 mg (in 1 tablet)
Excipients:
- Anhydrous Citric Acid
- Povidone K25
- Corn starch
- Lactose
- Magnesium stearate
The solution is clear, colorless.
Structure:
Active substance:
- Ethamsylate - 125/250 mg (in 1 ml and in 1 ampoule, respectively)
Excipient:
- Sodium disulfite
- Sodium bicarbonate
- Water for injections
pharmachologic effect
The drug has a hemostatic effect. In the walls of the capillaries, the drug can increase the synthesis of mucopolysaccharides, while normalizing their permeability and improving microcirculation. The drug can normalize platelet adhesion and stimulate the synthesis of coagulation factor. But the drug can not have any effect on prothrombin time, and also it lacks hypercoagulation properties and the ability in principle to thrombosis.
Pharmacokinetics
After administration of the drug, its maximum concentration in the blood is detected after 10 minutes. In the event that the drug was taken in the form of a tablet inside, then it is absorbed into the gastrointestinal mucosa very quickly and almost completely. The drug can penetrate the placental barrier, and it can also be easily excreted along with breast milk. That is why it is necessary to use this medicine with caution if the patient is pregnant or breastfeeding the newborn.
Indications dicinone
The instruction says that the drug is intended for the treatment and prevention of various capillary bleeding :
- Metrorrhagia
- Hematuria
- Menorrhagia
- Gum bleeding
- Nose bleed
- After and during surgery in various fields of medicine
- Intracranial hemorrhage in premature infants and newborns
- Diabetic microangiopathy
Before you start taking the drug, you must most accurately exclude the possibility of other causes of bleeding.
The drug in the form of a solution is intended for use exclusively in a hospital. In order to learn how to take dicinone, you need to contact your doctor.
Side effects of the drug "Ditsinon"
The instruction describes all the side effects that manifested or could appear in the control group during the testing of the drug dicinone. The drug, in addition, may have other side effects not included in the list below, due to the individual allergic reaction of the patient to one or more components of dicinone.
Side effects that may be associated with the peripheral and central nervous system:
- Dizziness
- Headache
- Paresthesia of the lower extremities
Side effects that may be associated with dermatological reactions of the body:
- Hyperemia of the face of the skin
Side effects that may be associated with the gastrointestinal tract:
- Epigastric severity
- Heartburn
- Nausea
Side effects that may be associated with CCC:
- Systolic Pressure Reduction
Contraindications to the use of the medicine "Ditsinon"
The instruction describes diseases in which taking the drug is not recommended:
- Children's hemoblastosis
- Acute porphyria
- Thromboembolism
- Thrombosis
- Sensitivity to Components
Medicinal interaction of the drug "Ditsinon"
The instructions in this section are presented in shortened form and may include other results of the interaction of the described drug with other drugs.
Do not combine this drug with others in the same syringe.
A combination with aminocaproic acid and sodium menadione bisulfite is possible.
Do not use with sodium bicarbonate and sodium lactate solution.