Chlorphenamine maleate is today widely used in pharmacology. This substance is part of a wide variety of drugs that are intended for the treatment of colds and respiratory diseases, as well as diseases of ENT organs. It is worth noting that this tool is an effective antihistamine.
Chlorphenamine maleate: pharmacological properties
This substance is a well-known blocker that acts on histamine H1 receptors. In connection with a similar mechanism of action, chlorphenamine maleate has excellent antihistamines as well as sedative properties. That is why this substance is used as a component of some combination preparations, since the severity of the allergic reaction decreases.
This tool acts on the capillaries, reducing the permeability of their walls. It also quickly narrows the lumen of the vessels and relieves swelling. In addition, chlorphenamine maleate relieves hyperemia of the mucous membrane of the nasal passages, sinuses and nasopharynx, thereby facilitating the patient’s breathing and general well-being. The same substance significantly reduces the amount of exudate and relieves allergic symptoms such as itchy eyes and sneezing.
It is worth noting that chlorphenamine maleate begins to act approximately 20-30 minutes after it enters the digestive system. The substance enters the bloodstream, where the corresponding blood protein binds to it. Thus, the transport of funds throughout the body. The duration of its effect is from 4 to 4.5 hours.
Chlorphenamine maleate: indications for use
As already mentioned, this substance has strong antihistamine properties, therefore it is used to suppress an allergic reaction and eliminate its main symptoms. It is used to treat rhinorrhea, sinusitis, allergic rhinitis, rhinosinusapathy. In addition, it effectively relieves allergy symptoms in infectious and acute respiratory diseases.
The tool is not used in its pure form, but is an integral component of some combination drugs. For example, it is part of such drugs as TeraFlu, Rinza, Antigrippin, Toff, Coldact, etc.
As for the dose of the drug, this indicator directly depends on the chosen drug.
Chlorphenamine maleate: contraindications and side effects
This substance has practically no contraindications. It is forbidden to take only patients who have hypersensitivity to its components.
Adverse reactions also do not appear too often. Since chlorphenamine maleate has sedative properties, taking it can cause drowsiness, weakness, and sometimes a lack of coordination. As a rule, side effects disappear after several days of administration.
Occasionally, a rash or dermatitis may occur. Some patients complain of dry mouth and nose, which is associated with a decrease in secretion of the mucous membrane of the upper respiratory tract. It is extremely rare that constipation, impaired urination, and double vision appear as an adverse reaction. Sometimes taking the drug may be accompanied by anemia.