In the article, we consider the instructions for use and price for the Nitroglycerin medication.
It is one of the most popular drugs that are often used to stop an attack of angina pectoris and an ischemic condition. This drug belongs to the group of antianginal drugs with a pronounced vasodilation effect. Next, consider the instructions for using this medication. In addition, in the end we will find out which medicines can be replaced and what people write in reviews.
Pharmacological form and composition
According to the instructions, "Nitroglycerin" is produced in various pharmacological forms, which only increases the degree of demand for this drug:
- It is made in the form of a spray. Instructions for the spray "Nitroglycerin" will be presented below.
- Injectable form in ampoules.
- The medicine is in the form of an alcohol solution.
- In the form of tablets. Instructions for "Nitroglycerin" are available in each pack.
- Dosage form in the form of films on the gum with nitroglycerin. The main indications for use are high blood pressure and angina attacks.
The active substance that is part of the drug is the substance of the same name nitroglycerin.
Pharmacological qualities of the drug
As the instructions indicate, "Nitroglycerin" acts as a peripheral vasodilator. It produces a direct effect on the structure of the venous walls. Under the influence of the drug, arterioles relax less, and large arteries with veins are more loyal to the main active component.
As indicated in the instructions for use, Nitroglycerin in tablets and other forms of release reduces the oxygen demand of myocardial tissue. Redistribution of coronary blood flow unloads the heart. The pressure in this case decreases within the pulmonary circulation.
So, then we will figure out in which cases the use of this medication is appropriate for treatment.
Main indications
In accordance with the instructions for "Nitroglycerin", the main indications are the following diseases:
- The presence of angina pectoris in the patient according to the vasospastic type.
- The development of unstable angina.
- The presence of spasms of the coronary arteries.
- The development of acute coronary syndrome.
- With myocardial infarction at any stage of development.
- Against the background of cardiac asthma and all types of pulmonary edema.
- With heart failure.
- Against the background of hypotension, amenable to drug control.
- To prevent complications from the work of blood vessels and the heart as part of tracheal intubation.
- With severe dyskinesia of the alimentary canal.
- Against the background of functional cholecystitis at the stage of exacerbation.
- With biliary colic.
The presented drug, despite its effectiveness and versatility, has many contraindications, which also need to be familiarized with.
The main contraindications
What else does the application instruction for Nitroglycerin tell us? The widespread use of the drug is still not always justified. There are some situations along with special pathological conditions when it is not possible to use this medicinal product for certain reasons:
- With individual intolerance of the presented pharmacological product. This is the main contraindication found in the list of prohibitions on all drugs.
- With a hemorrhagic stroke.
- Against the background of acute heart failure.
- With collapse and against the background of a state of acute anemia.
- Against the background of aortic mitral stenosis.
- In the presence of hemorrhage in the brain tissue.
- Against the background of toxic pulmonary edema, and, in addition, with shock.
- Against the background of severe and uncontrolled hypotension.
- With a low level of blood that circulates in the body.
- With kidney failure.
- Against the background of liver failure.
- During pregnancy and lactation.
- Against the background of angle-closure glaucoma, prone to sudden surges in pressure.
The instructions for use with "Nitroglycerin" price and reviews are not indicated. We will consider them below.
How to take the medicine?
People with chronic heart disease often experience this drug. It is often recommended by doctors to keep Nitroglycerin nearby, or at least replenish it with their home medicine cabinet. It is the responsibility of the attending specialist to conduct a detailed consultation of patients on how to properly take this drug in tablets. It is also necessary to clarify whether it is worth using this drug in the form of a spray.
Currently, alcohol solutions by the sublingual method are used extremely rarely. A more convenient means of use are tablets along with capsules. In that case, if it is required to use an alcoholic solution, then two drops of Nitroglycerin are dripped under the tongue according to the instructions for use.
The liquid form of the drug can be combined with a regular sugar cube. Experienced patients know how to take this medicine with sugar. To do this, a piece of sugar is simply put under the tongue, like a tablet.
How to use the tablets "Nitroglycerin" according to the instructions? As a rule, one or one and a half tablets are placed under the tongue until they completely dissolve. They should not be swallowed or chewed intensively. Otherwise, the therapeutic effect will be significantly reduced.
According to the instructions for use with the Nitroglycerin spray, at the first signs of an attack of angina pectoris, it is necessary to use the drug as follows: from a sitting position, 1-2 doses are applied by pressing the valve on or under the tongue, while holding your breath. If necessary, re-enter, but not more than three doses within 15 minutes. If there is a need to relieve an attack of angina pectoris, then the agent is reused at intervals of five minutes. For prevention, 1 dose is administered 5-10 minutes before the expected load or stress. Before use, the packaging does not need to be shaken; when sprayed, keep it upright, directly in front of you. The mouth should be closed after each spray, do not swallow immediately.
The maximum allowable daily dose of the drug is sixteen drops of an alcohol solution, which is served on sugar. Or you can use no more than six tablets of "Nitroglycerin" according to the instructions for use. Next, consider side effects.
Side effects
The instruction to "Nitroglycerin" should be strictly observed. When using the described drug for treatment, a bursting headache and dizziness, and, in addition, general weakness, impaired coordination of movements and vision, may occur. In addition, a decrease in pressure and extrasystole is possible. In patients treated with this medication, dyspeptic disorders may occur along with a sensation of heat and hot flashes.
In some cases, patients complain of the presence of severe headache, which provokes Nitroglycerin. At the same time, a validol tablet, which should be put under the tongue, helps well from headaches. And yet, if we talk about drugs like Nitroglycerin, it is worth noting that their use should always be coordinated with the attending physician. It is equally important to take into account the instructions.
Drug overdose
Reviews about the drug "Nitroglycerin" are more likely to be positive. The sad experience that is associated with this drug, usually people associate with exceeding the permissible doses of the drug. The key symptoms that indicate that the patient has taken too large a dose of Nitroglycerin, which caused an overdose, are:
- The development of severe collapse in people who are not prone to sudden pressure surges.
- The appearance of a severe headache that is not amenable to relief.
- The occurrence of drowsiness and a feeling of heat, and, in addition, severe vomiting.
- The occurrence of methemoglobinemia, dyspnea and tachypnea.
Medical staff for overdose patients immediately drop the head of the bed, and legs, on the contrary, raise above the head. The introduction of "Nitroglycerin" against the background of an overdose must be stopped. Possible antidotes are selected only by a doctor who evaluates the patient's condition. As a rule, ascorbic acid and methylthioninium chloride are used. Oxygen therapy may also be performed.
Analogues of the drug
Analogues of Nitroglycerin are used in those cases when the main drug cannot be used for any reason. The main substitutes for this medication are Angiolingual along with Nitragin, Nitroglycerol, Nitrocardiol, Nitrong and Trinitrol.
Medicinal combinations
Realizing why the Nitroglycerin preparation can be used, it is possible to quickly identify the main “partners” with which the presented vasodilator can be combined. All special patients should know about the existing pharmacological combinations.
Barbiturates can accelerate the assimilation of the active components of Nitroglycerin. Enhances the general hypotensive effect of this ethanol preparation along with quinidine, most diuretics, antidepressants and calcium antagonists. The analgesic effect can be enhanced in the case of a combination of Nitroglycerin with methionine, inhibitors, and, in addition, with salicylates of all kinds. Cholinolytics, corticosteroids and nervous system stimulants negatively affect the strength of the drug.
Cost
The cost of the drug is 45-115 rubles. It depends on the region and the pharmacy network.
Reviews about the drug
In the reviews, people call the drug "Nitroglycerin" a classic of pharmacology. People praise this medicine for helping to stop angina pectoris and other pathological conditions. Patients write that they always have this drug in their medicine cabinet just in case for peace of mind. Many indicate that they like to use a spray form more than tablets.
Consumers confirm that this product is easy to use and fast acting. People appreciate this drug and write that, thanks to it, in some emergency situations it is possible to save a person’s life or at least gain time.
We reviewed the medication "Nitroglycerin" instructions for use and reviews.