"Ibuklin" is considered a combination agent, the structure of which includes various non-steroidal anti-inflammatory compounds. The medication has analgesic and antipyretic pharmacological properties, therefore it is used in case of diseases with corresponding symptoms.
Release form "Ibuklin"
The medication is in tablet form for oral use. Its structure includes two main active components:
- Ibuprofen.
- Paracetamol.
In addition, the drug contains additional substances:
- Corn starch.
- Cellulose.
- Silica.
- Carboxymethyl ether.
- Salt of magnesium and stearic acid.
- Preservative E 200.
- Amphoteric oxide of tetravalent titanium.
- Hypromellose.
- Dye.
- Ethylene glycol polymer.
- Food supplement E 433.
- Talc.
The tablets have an oval shape, an orange tint, on the one hand there is a risk on them. They are packaged in blisters of ten pieces. What helps Ibuklin?
Pharmacological properties
The structure of the drug includes two active substances - ibuprofen and paracetamol, which belong to the therapeutic group of non-steroidal anti-inflammatory drugs.
The pharmacological effect of Ibuklin is due to the blocking of cyclooxygenase enzymes, which are responsible for the transformation of arachidonic acid into prostaglandins, which occurs in the source of inflammation.
A decrease in the level of arachidonic acid helps to reduce the severity of the manifestations of the inflammatory process that it provokes:
- Pain that occurs due to direct irritation of the sensory nerve endings with prostaglandins.
- Redness of tissues as a result of their increased blood supply.
- Swelling of tissues - the exit of plasma from blood vessels into the intercellular substance, which is due to increased permeability of the vascular wall.
Despite the fact that the active component of the drug "Ibuklin" refers to non-steroidal anti-inflammatory compounds, it has the following pharmacological effects:
- Ibuprofen inhibits the manifestations of inflammation both at the source of the pathological process and beyond its borders, it has anti-inflammatory and analgesic effects.
- Paracetamol - has a greater antipyretic effect. The anti-inflammatory effect of paracetamol in the lesion is less pronounced, since the substance is partially destroyed by white blood cell peroxidase enzymes.
The combination of paracetamol and ibuprofen in "Ibuklin" leads to its ability to have a pronounced anti-inflammatory, as well as analgesic and antipyretic effects. Moreover, these actions are higher than that of paracetamol or ibuprofen separately.
According to the annotation to "Ibuklin" it is known that after taking the tablet orally, its active components are rapidly and completely absorbed into the bloodstream from the lumen of the upper digestive organs.
They are well distributed in organs and tissues. Ibuprofen accumulates in large quantities in the structures of the musculoskeletal system.
When is the medication prescribed?
Indications for use of the Ibuklin tablet are the following conditions:
- Fever with an increase in body temperature, which is accompanied by infectious diseases.
- Myalgia (a pathology for which the occurrence of pain in the muscles is considered characteristic).
- Neuralgia (a pathological disease that progresses as a result of damage to certain nerves).
- Pain in the back.
- Toothache.
- Arthralgia (the periodic appearance of pain in the joints, in the absence of characteristic symptoms of their defeat).
- Algodismenorea (painful periods, which are accompanied by disorders of the central nervous system, as well as hormonal disruptions and emotional disorders).
What else does Ibuklin help from? The medication is prescribed for the complex treatment of pain, as well as the inflammatory process or an increase in body temperature as part of combination therapy. It does not affect the course of the disease and does not reduce its progression.
Drug restrictions
The use of the medication is contraindicated in the following pathological processes:
- Excessive sensitivity to active or complementary drug compounds.
- An ulcer with damage to the mucous membrane of the gastrointestinal tract or duodenum.
- Kidney disease.
- The pathological combination of bronchial asthma, as well as polyposis of the nasal mucosa and intolerance to non-steroidal anti-inflammatory substances.
- Pathological process in the blood system.
- Genetic lack of glucose-6-phosphate dehydrogenase enzyme.
- Damage to the liver.
- Inflammation of the small or large intestine.
- Age to twelve years.
- Third trimester of pregnancy.
According to the annotation to "Ibuklin" it is known that it is used with extreme caution in chronic cardiovascular pathological processes:
- Ischemia of the heart (damage to the muscles of the heart, which is caused by insufficient blood supply to the heart).
- Cerebral atherosclerosis (a systemic disease of the vessels of the brain).
- Heart failure.
In addition, the drug is contraindicated in:
- Diabetes mellitus (endocrine disease, which is associated with impaired glucose uptake and results from insulin deficiency).
- Pathologies of peripheral arteries (a feeling of discomfort or the development of pain in the lower extremities when walking).
- Smoking.
Before starting Ibuklin therapy, it is necessary to make sure that there are no restrictions.
Mode of application
Tablets are taken orally as a whole, without chewing, washed down with water, two to three hours after a meal. The dosage regimen for Ibuklin for adult patients is 1 tablet three times a day, for children from twelve years old - 1 tablet twice a day.
The duration of therapy with an increase in temperature should not exceed three days, with pain - no longer than five days. If symptoms persist beyond this time, the doctor should be consulted from the start of treatment.
According to the annotation to "Ibuklin" it is known that adolescents who are over twelve years old, weighing more than forty kilograms, are prescribed 1 tablet a day twice a day. The Ibuklin therapy for lowering the temperature can be carried out no longer than three days.
The use of the drug as an analgesic is possible within five days. If you need to continue treatment, it is important to consult a doctor first.
According to the annotation to "Ibuklin Junior", the dosage of the drug depending on body weight will be as follows:
- Weighing from eleven to fifteen kilograms - 1 tablet every eight hours, three times a day.
- With a weight of sixteen to twenty-one kilogram, the dosage of the drug is 1 tablet every six hours, four times a day.
- With a weight of twenty-two to forty kilograms - 2 tablets once every eight hours, three times a day.
- With a body weight of more than forty kilograms, the minimum concentration of the active substance for adult patients is prescribed.
What side effects does the drug provoke?
According to the instructions for use with Ibuklin, it is known that taking tablets can lead to the following negative manifestations from various systems in the body:
- Gastropathy (gastroenterological disease, which is characterized by changes in the mucous membrane of the stomach and intestines).
- Nausea.
- Vomiting.
- Pain in the abdomen.
- Loss of appetite.
- Flatulence (increased flatulence in the stomach).
- Diarrhea (a pathology in which the patient has frequent bowel movements, while the feces become liquid).
Less commonly, the following conditions may appear:
- Erosion of the mucous membrane of the digestive tract.
- Hepatitis (a liver disease of viral origin).
- Pancreatitis (a disease in which the pancreas becomes inflamed).
- Dryness of the oral mucosa.
- Aphthous stomatitis (damage to the oral mucosa, which is caused by a violation of the surface layer of the mucous membrane and the formation of aphthae).
From the central nervous system, the following ailments can occur:
- Dizziness.
- Hallucinations (visual or auditory image that appears in the mind without an external stimulus).
- Loss of sleep.
- Nervousness.
- Depression (a mental disorder characterized by mood swings and decreased ability to have fun).
- Excitation.
- Confusion.
- Aseptic meningitis (a disease that is localized in the spinal cord and brain).
In addition, other negative manifestations and conditions may appear:
- Hearing impairment.
- Toxic damage to the optic nerve.
- Loss of vision.
- Bifurcation in the eyes.
- Scotoma (blind spot in sight).
- Noise in ears.
- Amblyopia (persistent visual impairment that is not associated with the pathological process of the visual analyzer).
- Anemia (a condition caused by low hemoglobin in the blood).
- Thrombocytopenia (a disease that is caused by a decrease in platelets below normal).
- Agranulocytosis (a pathology in which there is a decrease in the level of white blood cells due to granulocytes and monocytes).
- High blood pressure.
- Tachycardia (a condition characterized by frequent heart contractions).
- The development of heart failure.
- Dyspnea.
- Bronchospasm (a disease that occurs when contracting smooth muscles of the bronchi and reducing their lumen).
- Jade (an inflammatory lesion that often leads to the transformation of paired organs tissues).
- Acute violations in the functioning of the kidneys.
- Nephrotic syndrome (a disease characterized by impaired protein-lipid metabolism and swelling).
- Polyuria (increased urine output).
- Rashes and itching of the skin.
- Nettle rash (a skin disease with the appearance of severely itchy blisters).
- Quincke's edema (a reaction to the effects of various factors, often having an allergic origin).
- Allergic conjunctivitis (allergic damage to the mucous membrane of the visual organ).
- Anaphylactic shock (a state of sharply increased body sensitivity).
- Exudative erythema (a disease that is an inflammatory lesion of the skin and mucous membranes).
- Toxic epidermal necrolysis (a serious illness that is accompanied by rejection of the surface layer of the epidermis and impaired functioning of internal organs).
In addition, glucose levels may decrease under the influence of the drug in the blood. The likelihood of bleeding from the stomach and the formation of erosion, ulcerative lesions of its mucous membrane increases with prolonged use of Ibuklin tablets. The appearance of adverse reactions is considered the basis for stopping the medication.
Features
Before starting therapy, it is important to carefully read the instructions for use with Ibuklin. There are a number of specific special instructions that you should pay attention to:
- The joint use of the drug with other non-steroidal anti-inflammatory drugs is excluded.
- If necessary, the simultaneous use of drugs that inhibit blood coagulation, regular laboratory monitoring of blood system parameters should be carried out.
- If you need longer use of tablets, it is necessary to monitor the indicators of the functional state of the blood.
- Do not use the drug with alcohol during drug therapy to prevent toxic effects on the liver.
- The use of a medication may distort some indicators of laboratory tests, including glucose, as well as uric acid in the blood.
According to the instructions for use and reviews of the drug, it is known that the use of "Ibuklin" during pregnancy is possible, but only as prescribed by the doctor, if the likely benefit to the expectant mother outweighs the risks to the fetus.
The use of a medication does not directly affect the speed of psychomotor reactions and attention. Nevertheless, at the time of its use, it is necessary to abandon activities that involve increased attention.
In pharmacies, pills are dispensed without a doctor's prescription. If you have any questions or doubts regarding their admission, you should consult with a medical specialist. Can Ibucline be used for breastfeeding?
Lactation and pregnancy
If there is a need for Ibuklin therapy during an "interesting position" and lactation, the likely benefit of the therapy and the risk are initially determined.
In the first six months, short-term drug therapy is possible. With the short-term use of "Ibuklin" during pregnancy and during breastfeeding, as a rule, it is not necessary to transfer the child to artificial mixtures.
Substitutes
Ibuklin has a number of analogues:
- Nurofen
- Next.
- Ibuprom.
- Ibuprofen
- "Brustan."
- Ketoprofen.
- Ketonal.
Before replacing a medicine, you should consult a doctor.
Drug Interaction "Ibuklin"
The combined use of drugs that contain ibuprofen and acetylsalicylic acid as active ingredients reduces the anti-inflammatory and anti-aggregation effect of the latter.
When Ibuklin is combined with glucocorticoids, as well as ethyl alcohol and corticotropin, it increases the likelihood of erosion and ulcerative lesions in the gastrointestinal tract.
The drug activates the effect on the body of thrombolytic agents, colchicine. As a result, the risk of developing hemorrhagic complications increases. In addition, the hypoglycemic effect of insulin and oral medications with a hypoglycemic effect increases.
When combined with antihypertensive drugs and diuretics, their effectiveness is slightly reduced. The analgesic effect of "Ibuklin" enhances caffeine.
When using gold medications, as well as Cyclosporine with ibuprofen, nephrotoxicity increases. With the simultaneous use of antacid medicines, the absorption of Ibuklin is reduced.
How to store the drug?
Information on the conditions and shelf life for Ibuklin can be found in the instructions for use. The medication "Ibuklin" must be kept in a dry place, at an air temperature of no more than plus twenty-five degrees. The price of the drug ranges from 100 to 180 rubles.
Reviews about "Ibuklin"
The responses of doctors and patients confirm that the drug effectively lowers body temperature in both adults and children.
According to reviews of "Ibuklin" from a headache, it is known that it instantly eliminates the ailment, and at high temperatures it eliminates fever. Adverse reactions are extremely rare.
Getting acquainted with the responses about "Ibuklin Junior", it can be noted that in most cases, parents note diarrhea, abdominal pain as side effects in children.
According to reviews of "Ibuklin" from a headache, it is known that the drug exhibits increased effectiveness in eliminating the ailment, the therapeutic effect occurs quickly.