In the article, we consider the instructions for use and price for Adelfan tablets.
The drug is a medicine that helps in the presence of hypertension. Next, we consider the instructions for its use, and in addition, we find out what indications are for its use. In addition, we will get acquainted with its analogues and find out what people write in their reviews about this medicine.
Structure
According to the instructions for use with Adelfan, there are two active components for this medicine - these are reserpine and dihydralazine. The output format is white tablets. On tablets, a separation mark is applied, which indicates that the pill can be broken when used. The antihypertensive drug presented is a combination drug. Its two-component combination provides speed and a noticeable effect.
Mechanism of action
As indicated by the instructions for use, the ingredient reserpine dilates blood vessels and acts as a psychoactive drug that has a neurotropic effect on the body. This medicine affects the human nervous system. The drug normalizes the state of blood vessels. The ingredient reserpine is a sympatholytic. Substances of this category slow down impulse transmission from the sympathetic centers of the nervous system to various organs.
Indications for use
Instructions for use with "Adelfan" reports that the drug is prescribed to patients exclusively in the presence of hypertension. This narrow-profile medication is used to achieve the following goals:
- If necessary, increase blood flow.
- In order to stimulate metabolic processes.
- For a sedative effect.
- To reduce vascular tone.
But there is only one indication for the therapeutic use of the drug - the presence of hypertension. Thus, the main purpose of the drug is to reduce pressure.
According to the instructions for use, at what pressure can Adelfan be prescribed?
Contraindications
Any synthetic component that interferes with the processes produced by the body has various contraindications. These or other tablets may not suit everyone. Adelfan is no exception and cannot be used in a number of the following cases:
- In the presence of pheochromocytoma.
- The patient’s intolerance to the substances that make up the drug, that is, any of its components.
- Against the background of depression or a tendency to it.
- In the presence of thyrotoxicosis.
- Against the background of peptic ulcer of any parts of the digestive system.
- In the presence of tachycardia or acute phase of a heart attack.
- With aortic stenosis.
- Against the background of severe insufficiency of liver functions.
- With epilepsy and chronic pericarditis.
The presence of pregnancy is also a reason for refusing this drug.
Relative contraindications
Instructions for use with Adelfan informs that it is recommended to take these pills with caution in the following cases:
- In the presence of diabetes.
- Against the background of atherosclerosis.
- With bradycardia and in old age.
- Against the background of gallstone disease and with gout.
- In the presence of intraventricular blockade, when cardiac conduction is impaired.
- Against the background of erosive gastritis.
Price, analogs and instructions for the use of "Adelfan" are of interest to many.
Side effects
The two components that make up Adelfan can produce powerful work in the human body. They mutually complement each other, but each carries out the functions defined by the chemical formula. Some patients may experience allergies while taking this medicine. But this is only a small part of the adverse reactions.
According to the instructions for use and reviews, "Adelfan" is difficult to tolerate by the human body and can cause a lot of side effects, for example:
- The digestive system can respond with nausea, increased acidity, increased salivation, vomiting, ulceration of the mucous membranes, and bleeding.
- Perhaps the development of dry mouth, along with bradycardia, extrasystole, fainting, swelling, dizziness and headache.
- Orthostatic hypotension, restless sleep, and facial skin hyperemia are very likely.
- Extrapyramidal disorder can manifest itself in the form of motor neurological disorders, namely in the form of tremors, tics, parkinsonism, dystonic syndrome, and so on.
- Likely nasal congestion due to swelling of the mucosa.
- Cerebrovascular diseases, that is, brain pathologies that are caused by the state of its vessels, are possible. Moreover, cerebral circulation is very often impaired.
- Probably the appearance of irritability, anxiety, glomerulonephritis, cerebral edema and anorexia.
- Perhaps the development of thrombocytopenia and low hemoglobin, and in addition, jaundice. The instructions for use with Adelfan are best studied in advance.
- Against the background of taking this medication, people can quickly gain weight or, conversely, lose weight.
- In addition, manifestations such as blurred vision along with diseases of the reproductive system, hearing loss, eczema, shortness of breath, imbalance, nosebleeds, decreased attention and lethargy are noted.
This is also described in the instructions for use.
The price of "Adelfan"
The price of the drug was always democratic, even during the period of the total rise in price of medicines, it did not rise above one hundred and fifty rubles. At the pre-reform cost, this medicine cost the customers only ten rubles. This price held until 2012. But at present, Adelfan is considered an obsolete drug and now in pharmacies its analogues are mainly sold, the price of which starts from one hundred and fifty rubles. At present, Adelfan can be ordered through any online pharmacy for one hundred and twenty rubles. It is worth emphasizing that any of its modern counterparts today cost consumers much more.
Mode of application
According to the instructions for use, "Adelfan" at a pressure must be taken twice or thrice a day, which is determined individually in each case, since when prescribing a medicine, the doctor should focus on the initial indicators of patient pressure, and in addition, on the response of his body.
What is not recommended?
Exceeding the dosage and taking the drug more than three times is not recommended. Otherwise, you can increase the risks of side effects. Eating food does not reduce the activity of the components of this medicine. Thus, this medication can be taken regardless of the diet.
This is confirmed by the instructions for the use of "Adelfan." Price and reviews are also presented in the article.
Drug overdose
In no case should you exceed the dose of this drug, since such actions are fraught with serious malfunctions in the life of the body.
For example, the following violations may occur:
- A sharp drop in pressure. Such an effect for hypertensive patients is sometimes more dangerous than a crisis.
- Inhibition of respiratory function is likely.
- Extrapyramidal disorders are possible.
- The appearance of angina pectoris, confusion, nausea or vomiting.
- The development of arrhythmias and seizures.
- Falling into a coma is not excluded.
We have reviewed the instructions for the use of "Adelfan." Analogues of the drug will be discussed later.
Analogues of the drug
The medicine has been recognized as obsolete and lagging behind in quality for three years. Therefore, it is worth considering its modern counterparts. There are a lot of drugs that lower blood pressure in pharmacies today, and their choice is not easy. Any medicine should be selected strictly individually and exclusively by a specialist. So, next we consider the most popular analogues of this drug:
- The drug "Reserpine." These drugs have the same active ingredient. Therefore, their properties are largely the same.
- The drug "Adelfan-Ezidrex". This drug is many times more expensive than Adelfan. And by side effects, the substitute is hardly inferior to an obsolete remedy. Adelfan-Ezidrex is positioned by manufacturers as a means taken once a day. The advantages of this substitute is that it does not cause face hyperthermia and diarrhea, unlike Adelfan. Also, this drug is supplemented by another, third component, which is hydrochlorothiazide. Pharmacists call this drug composition improved. Thus, if the patient has healthy kidneys, then the elimination of the medicine will pass without any problems in just a day.
- The drug "Captopril." This medicine is based on the action of the active ingredient of the same name entering it. This drug is a quick-acting medicine, since after its use the pressure drops in a matter of minutes, which, of course, is very convenient against the background of a spontaneous and instantly developed crisis, when it is necessary to quickly stop it. But in the event that the symptoms increased gradually, then the pressure indicators should also be reduced smoothly. Then the choice must be given to other medicines. As for Captopril itself, it is often used on calls by ambulance paramedics. After taking it under the tongue, it is rapidly absorbed and works almost immediately.
- The drug "Nifedipine" also reduces pressure very rapidly. This drug is a calcium channel blocker and is prescribed for patients whose vessels can withstand sudden changes in pressure. In the presence of severe atherosclerosis, pressure drops are very dangerous, especially a sharp decrease. "Nifedipine" is an active antispasmodic, increasing the heart rate.
- Enalapril is considered to be a slow-acting drug, and it will not work as a quick aid. This medication spares the kidneys, reducing the burden on the heart. Sometimes it can reduce pressure quickly enough, however, this largely depends on the individual characteristics of the patient.
- Enap is currently a commonly prescribed and relatively cheap drug. It is almost identical to Enalapril.
- The drug "Trirezid" is similar in composition to "Adelfan-Ezidrex." Instructions for use confirm this information. True, it additionally contains potassium chloride, which prevents hypokalemia.
- Means "Veroshpiron" reduces pressure due to its diuretic effect. True, it has a lot of side effects and there are various contraindications.
What is the difference between them?
Most of Adelfan’s analogues are distinguished by prolonged exposure. Additional components included in the composition of these drugs, eliminates some possible adverse reactions and provide a mild effect. Each of the analogues also has new qualities that are not always positive. But you still have to make a choice and stop at something. Unfortunately, side effects when taking this or that medicine cannot be avoided, even if they are hardly noticeable. Any pill often negatively affects the human body. Therefore, in order to choose the most suitable and gentle drug, you need to contact a specialist. This is indicated in the instructions for use with the Adelfan tablets.
Next, we find out what consumers write about the drug, which for many years took it from high blood pressure.
Reviews about the drug
In the reviews, many people express dissatisfaction with the fact that the drug "Adelfan" is recognized as obsolete and ineffective. Consumers write that they took it for about thirty years, and during such a long treatment he always helped them. In this regard, people write that they believe that the pharmaceutical market specifically removes cheap drugs so that patients spend a lot of money on similar expensive medicines.
Thus, many patients report that "Adelfan" is a very effective medical tool that helps to cope with hypertension. Adverse reactions associated with its use have been reported that this medication can cause nausea, swelling, and rarely tremor. But also people say that in general this medicine, even despite the adverse reactions that it causes, is tolerated by the body, and most importantly it effectively lowers blood pressure. In this regard, patients with hypertension do not see any risks associated with its use.
Thus, consumers are saddened by the fact that the medication has recently been discontinued and express their dissatisfaction with the fact that now they are forced to buy expensive medications that are no better tolerated, and in addition, they do not exceed their effectiveness.
We reviewed the Adelfan product, instructions for use, price, reviews and analogues.