The drug "Furazolidone" refers to antimicrobial medications. The mechanism of its action is the ability to inhibit the activity of bacteria. The special sensitivity of the drug “Furazolidone” is noted in relation to staphylococci and streptococci, gram-negative bacteria: salmonella, Klebsiella, enterobacteria, Giardia. Pathogens of paratyphoid, dysentery, and typhoid fever also react to the active substance of the drug , and drug resistance develops slowly in them.
The drug "Furazolidone" has a weak absorption, the medication is taken only orally, only 5% of the substance is excreted unchanged from the body, while the urine is colored brown.
The drug "Furazolidone." Indications for use
First of all, the drug is prescribed for patients with infections, to the causative agents of which its high sensitivity is observed. These are diseases such as dysentery bacillus, trichomonas, typhoid giardia. The positive effect of treatment with the drug "Furazolidone" is noted in cases of infection of burn wounds, in today's medicine, often the drug has been used for the medical treatment of alcoholism. Although such an ailment is not an obligatory reason for taking the drug “Furazolidone”, the instruction indicates the need arises if other drugs have not been effective enough or if there are a number of contraindications to them. As a result of taking the drug in an alcoholic, the body develops a reflex negative reaction that contributes to the appearance of aversion to alcohol-containing products.
The drug "Furazolidone." Contraindications
It is probably difficult to find a drug that has only positive effects. Each medication consists of certain chemicals, it happens that an overdose, some types of diseases or allergic reactions to the components of the drug lead to negative consequences. In such cases, it is customary to talk about contraindications to the use of the drug. Furazolidone also has them. Treatment with this antibacterial agent is not recommended if the patient has one of the following symptoms:
- renal failure (chronic form);
- pregnancy or lactation;
- individual intolerance to drugs of the nitrofuran group;
- the age of the baby up to a year;
- deficiency of glucose-6-dehydrogenase.
For diseases of the central nervous system, doctors also do not recommend taking the drug “Furazolidone”, the instruction warns of the possibility of negative consequences for the nervous system of the patient.
The medicine "Furazolidone." Side effects of the drug
During treatment with Furazolidone, in some cases, side effects of varying severity occur. In the first place among the negative manifestations of the drug is the gastrointestinal system. Patients experience symptoms of mild poisoning, vomiting and nausea occur, a decrease in appetite, sometimes people complain of headaches and abdominal pain. Allergic reactions rarely appear in the form of rash and itching.
If one of the signs is found, it is necessary to inform the doctor about this and temporarily stop treatment until a new appointment is received.
I especially want to dwell on the undesirability of taking alcohol and the Furazolidone drug at the same time, the instruction indicates the occurrence of a number of side effects, which are often very pronounced. The patient has a burning sensation in the body and fever, the patient complains of strong compression in the occipital part, sometimes such carelessness leads to an increase in blood pressure and tachycardia.
An overdose of the drug “Furazolidone” looks dangerous, the instruction warns of the possibility of developing hematotoxicity, toxic hepatitis, and neutrotoxicity.
To minimize the occurrence of side effects, the drug is recommended to be used only before meals and with plenty of water.