Effective and safe choleretic drugs

Bile is a biological fluid that is formed as a result of the work of liver cells. Like all other biological processes in the human body, the outflow of gallbladder secretion must be constantly carried out during meals, otherwise serious health problems can arise. If stagnation occurs, then after the examination, experts prescribe choleretic drugs to patients.

The role of bile in the body

In humans, a small sac called the gall bladder is located under the liver. It is he who serves as an accumulating vessel, from where the release of biological fluid occurs during food intake. As soon as food enters the stomach, a substance is released from the gallbladder, which then passes into the duodenum and simplifies the mechanism of digestion of food products.

The main functions of bile secretion:

• stimulation of the digestion process, improvement of intestinal motility;
• promotes the best assimilation of nutrients, vitamins;
• the breakdown of fats and the removal of various toxins and other decay products.

The liquid itself is dark brown, yellow or greenish in color, and tastes bitter. If the work of the gallbladder is disrupted and stagnation of bile occurs, such a violation can be determined by a number of specific symptoms:

• bitterness in the mouth (even on an empty stomach);
• vomiting of bile is possible, which occurs, as a rule, with an empty stomach (signals a strong accumulation of secretion);
• pain in the right hypochondrium;
• nausea;
• itching of the skin and feet;
• yellow skin tone;
• periodic swelling in the neck and chin;
• problems in the throat (tickling, hoarseness, belching);
• whitish coating on the tongue;
• discomfort in the heart (especially after eating);
• chronic fatigue;
• nervous state and aggravation of fears (mainly at night).

Ignoring the symptoms can only aggravate the ailment and lead to consequences such as the appearance of sand and stones in the bladder.

Causes of the disease

The main detrimental factors that directly affect the work of the gallbladder include:

• increased nervousness
• instability of the emotional background;
• cholesterol food intake;
• unbalanced diet, lack of a rational diet;
• very low locomotor activity;
• excess weight;
• taking specific medications;
• weak abdominal muscles.

Here, I would like to separately analyze such a reason for the violation of the outflow of bile as an excess of the gallbladder. Cholagogue with this diagnosis is also prescribed. But first about the pathology itself.

So, the inflection of the gallbladder is a common pathological condition of the anatomical form of the organ. As a result, there is a violation of the functions of the organ - a decrease in synthesis and a deterioration in secretion, stagnation of bile, and so on.

The excess can be congenital (the pathology begins in the fifth week of the pregnancy period, when this organ is formed in the embryo) or acquired. And if in the first option it is hardly possible to do something to prevent pathology, then in the second one the person is often guilty.

Causes of acquired excess in an adult:

• an increase in the digestive organ or those adjacent to it (kidneys, liver);
• hypermobility of the bladder;
• disturbed (or its complete absence) diet - starvation, then overeating;
• the use of fatty, spicy and smoked foods;
• bending under the influence of physical exertion, in particular, lifting weights, a fixed state in a sitting position, sharpness of movement;
• obesity;
• the use of alcoholic beverages (especially carbonated ones);
• omission of internal organs during sudden weight loss (due to diets as well).

Usually, for violations caused by such a cause, no lists of symptoms are distinguished. But if the deformation of the organ is obvious, then the signs include:

• constipation / diarrhea;
• loss of appetite
• bouts of nausea / vomiting;
• heartburn / burping;
• bitterness in the oral cavity;
• pain in the right hypochondrium;
• bloating and heaviness after meals;
• increased sweating.

In this case, dull pain can be given not only to the right side, but also to the collarbone, spine and even to the cervical region.

The degree of excesses also varies, and depending on the state of neglect, symptoms may intensify. Accurate diagnostics can only be carried out by a specialist.

Treatment of bile stasis

When there is a malfunction in the gallbladder and the removal of its secret, you must consult a doctor to determine the cause of the disease and its elimination.

As medical practice shows, specialists use complex therapy, combining diet, physical education and taking choleretic drugs.

Medications are intended to eliminate pain syndromes, simplify the mechanism of throwing substances, prevent relapse of the disease, as well as block secondary pathologies.

Prescribed choleretic drugs for stagnation of bile are classified into three groups:

• antispasmodics;
• cholekinetics;
• choleretics.

Each group of the above is assigned depending on the mechanism of action of active substances, as well as depending on the method of application of the drug.

Group of cholespasmolytics

Medicines of this group have a different origin and are aimed at reducing spasms (tone) in the gallbladder and bile ducts (including intrahepatic), and facilitating the excretion of bile into the intestines.

These choleretic drugs are prescribed for stasis secretion and are designed to:

• reduce spasms of the biliary tract;
• reduce sphincter spasms;
• eliminate pain in the liver;
• improve the process of excretion of bile during spasm of some areas

Cholespasmolytics are usually prescribed as immediate relief for various diseases of the liver and nearby organs. Such drugs are taken in short courses. Their main goal is to relieve pain with increased activity of the smooth muscles of the digestive tract. indications for use:

• cholelithiasis;
• hepatic colic;
• impaired motility of the biliary tract;
• cholangitis;
• cholestasis;
• cirrhosis of the liver;
• pain cramps due to an increase in tumors.

In this group, drugs are divided into subgroups:

• vegetable - "Holagol" and various tinctures: peppermint, St. John's wort, lemon balm, marigold flowers, arnica, elecampane and more;
• artificial (derived synthetically) - "Papaverine", "Aminophylline", "Duspatalin", "Drotaverin", as well as their analogues;
• anticholinergics (drugs that block or weaken the effects of acetylcholine, which is responsible for the presence of nervous system excitation) - Atropine, Metacin, Platifillin, Besalol, Spazmolitin.

Cholekinetics group

Cholagogue drugs of this group are designed primarily to restore the function of reducing the bile ducts, thereby returning an increased tone of the bladder. Such drugs are prescribed for chronic forms of cholecystitis and hepatitis, gastritis (provided that the level of hydrochloric acid secretion is zero or reduced), before conducting duodenal sounding.

What of this group is prescribed for bile stasis? Cholagogue drugs "Berberis plus", "Sorbitol", "Xylitol", "Holosas", "Flamin", "Mannitol", "Magnesia".

Choleretic group

This category of drugs is aimed at improving the functional abilities of the liver, contributes to an increase in bile volumes. Medicines of this group are prescribed for:

• cholestasis;
• violation of the stool (constipation);
• chronic form of liver diseases (steatosis, hepatitis);
• chronic inflammatory processes and biliary dyskinesia.

Choleretics are also divided into subgroups depending on their origin:

• True - these preparations include the extraction of natural bile from animals, plant extracts and biological active substances of animal origin. The most famous means: Hologon, Aplohol, Cholenzym, Liobil.
• Artificial (they are based on components that have been chemically excreted) - combined preparations that have antibacterial, antispasmodic and antiflogistic effects. Representatives of this subgroup: Osalmid, Tsikvalon and Nikodin.
• Vegetable (with choleretic effect) - aimed at reducing the viscosity of bile secretion, activate its secretion and emissions. At the same time, they affect the work of the liver, bringing it to normal. The list of choleretic herbal preparations of this subgroup is quite large, but the most popular are Hofitol, Febichol, Insadol, and Travohol.

Still distinguish the type of medicinal drugs that are designed to reduce the index of supersaturation of bile with cholesterol. Such funds are prescribed mainly to prevent the formation of gallstones, in addition, they help dissolve existing ones. Bright representatives of this group: Ursolit, Ursodeks, Urdoks and Livodeks.

Also, choleretic drugs are divided according to the method of use, regardless of group. Here, the gradation occurs according to the principle of taking the medicine, that is:

• on an empty stomach, 15-30 minutes before a meal (all drugs, tinctures, herbal decoctions are included in this category) - they can stimulate the secretion of food glands;
• while eating - preparations with substitutes for gastric juice;
• after food - preparations with bile substitutes.

And here, a very important nuance will be precisely the time period for taking medications. It is recommended to drink the product at the same time. Do not worry: each drug has its own instructions for use, in which the reception algorithm is clearly spelled out.

Acquired Therapy

If the bend is congenital, there is no particular need for therapy. The patient can even live with such a diagnosis all his life and not feel any discomfort. But a person with an acquired form of the disease necessarily needs treatment.

In excess, choleretic drugs are prescribed with antispasmodic and choleretic action. Only a doctor can choose an effective treatment program taking into account the course of the disease and the individual characteristics of the patient. Moreover, the program should be comprehensive and include, in addition to medicines, physiotherapy, physiotherapy exercises and a special diet.

What drugs should be used for biliary excess? There are a lot of choleretic drugs, so we list only those that doctors usually prescribe to their patients:

• Gepabene. The main goal is to support the functions of the liver, the elimination of bile secretion, and the removal of pain.
• "Allohol" - its basis is cattle bile, nettle and garlic extracts, which stimulate fluid production in the gall bladder and improve duct function.
• "Flamin" is a complex drug with antibacterial, anti-inflammatory, choleretic, analgesic and antispasmodic effects.
• "Odeston" is an excellent tool that relieves pain, promotes the release of bile secretion, but has side effects and contraindications, which must be taken into account before using the drug.
• "Hofitol" - helps to organize the protection of the liver, eliminate stagnation of bile, and also relieves pain.

Ursofalk (and its analogues) is also often prescribed for gallbladder congestion with choleretic drugs. But it is usually taken in cases when gallstones are found.

Cholagogue for children

It should be borne in mind that the treatment of diseases of the gallbladder in an adult will differ significantly from the treatment of children. And not every drug is suitable here.

In general, medical practice tries to exclude such cases when children under 12 years of age are prescribed medications to improve the outflow of bile. By the way, like pregnant women. But if the situation is such that drug therapy will bring more benefits than harm, resort to taking medications. The doctor will calculate the dosage individually based on body weight and the condition of the baby.

So, with problems with the bile, a small patient will be disturbed by symptoms that are almost similar to those observed in adults, namely:

• loss of appetite;
• the presence of a whitish plaque in the tongue;
• loose stools / constipation;
• nausea and vomiting;
• belching with an unpleasant odor;
• bitterness in the mouth;
• very poor transfer of physical activity;
• headaches, fatigue and apathy;
• pain in the right side and so on.

If after the examination the ailment is confirmed and the baby can’t avoid taking the medicine, you should still know which choleretic drugs are not forbidden to him. The choice is not so small.

For example, "Holaflux" is a herbal choleretic drug, which is prescribed for chronic forms of cholecystitis, disruption of the bladder and its ducts. Helps relieve the outflow of bile. They release this medicine in the form of herbal tea so that it can be prepared in the form of tea (which makes it very easy for the baby to take the medicine). Instructions for use confirm its safety, since the drug has no side effects.

But the herbal preparation "Holagogum" can be prescribed to eliminate the main symptoms, and when recovering from therapy. Available in capsules, which contributes to the rapid dissolution of active substances directly in the stomach.

What else helps the outflow of secret during stagnation? A good choleretic drug is Allochol. Also a natural remedy. Affects the work of the liver, improving the release of bile. Its composition, in addition to plant components, includes dry animal bile.

"Cholenzym." A combination drug that contains digestive enzymes. It includes, like the previous preparation, dry animal bile mixed with herbs.

Flaming. This drug is simply the favorite of many parents who confirm its effectiveness. The composition of the herbal preparation includes immortelle, which stimulates the discharge of fluid from the bladder. The forms of its release simply do not have boundaries: ointments, tablets, teas, suspensions. Parents also emphasize that this medicine is still worth taking from 5 years.

"Barberin" tablets are contraindicated only for pregnant women. A herbal remedy is produced in tablets, which include the active substances of the roots and leaves of barberry. Cholagogue with antispasmodic effect.

Odeston is prescribed for children over the age of 10 years. A wonderful herbal medicine that comes in pill form. Its task is not only the synthesis and release of bile secretion, but also the prevention of the formation of cholesterol plaques.

Maternity Medicines

In cases where a woman has a fetus, choleretic drugs with stagnation in the liver are selected with the exception of the possibility of stimulating uterine contractions. An equally important nuance is the ability to transport the drug through the placental barrier.

Doctors usually prescribe such drugs: "Holosas", "Atropine", "Papaverine", magnesia and valerian are also in demand.

Forms of release of drugs

The bulk of the choleretic drugs taken with stagnation of bile in the gallbladder is presented in the form of tablets and herbal preparations. But there are other dosage forms: suspensions and powders.

The group of suspensions includes such drugs:

• "Holosas" - is issued in the form of a viscous syrup of a brown (dark yellow) shade. The suspension has a very pronounced aroma of rose hips, since the active substance of the drug is the fruits of this plant. The excipient is sucrose. The preparation is contained in dark-colored glass bottles with a volume of 130 and 300 ml.
• Ursofalk is a homogeneous suspension of white color, which has a persistent aroma of lemon. Small air bubbles are acceptable. The active substance is ursodeoxycholic acid. Available in bottles of dark glass, volume - 250 ml.
• "Hofitol" - a thick solution based on water, which includes the extract of leaves of field artichoke (active substance). Has an orange flavor. The drug solution also goes on sale in a dark-colored glass container with a volume of 120 ml;
• "Holagol" is a medicine in the form of drops that are taken orally. The volume of the dark glass bottle containing the drip solution is 10 ml. Comes with a dropper dispenser. The composition of the drug includes several active ingredients, such as: peppermint and eucalyptus essential oils, frangulomodine, turmeric root, magnesium salicylate. The peculiarity of these drops is the method of taking the drug - before eating, you need to drip up to 10 drops per 1 piece of refined sugar (and so three times a day). With severe colic, the dose can be increased to 20 drops in 1 dose.

What other choleretic drugs exist? With stagnation of bile in the gallbladder, doctors often prescribe drugs in powder form, for example:

• "Deholin" is a preparation in the form of a colorless powder, which is highly soluble in water. It tastes bitter. The volume of the bag is 5 g. Also on sale you can find 5-20% solutions for intravenous injection. The solution has a slightly alkaline reaction. It is able to increase the secretion of bile for 3 minutes, maintaining its effect for about 3 hours.
• "flaming" - small granules of various shapes of light yellow color (gray with a yellow tint is allowed). It is odorless, but a slightly perceptible specific aroma is acceptable. The granules are contained in paper packaging weighing 1.38 grams. The active substance is flaming (flowers of the sandy immortelle).

Regardless of the form of the drug being manufactured, it is strongly recommended that you consult a specialist before starting therapy. Only a qualified doctor will be able to prescribe a suitable choleretic drug that will help cope with the disease. Finally, we list the most popular means, based on patient reviews.

The best choleretic drugs

A person suffering from stagnation of bile, tries to eliminate the cause of his poor health as soon as possible. Sometimes you can cope with the help of folk remedies, but more often it happens that people do not pay attention to the body's signals and ignore the first symptoms. In advanced cases, an integrated approach with the use of drugs is required. Of course, we are talking about the safest and most effective choleretic drugs. With stagnation of bile in the liver or gall bladder from the whole assortment, the first thing is often prescribed "Allolokh". Its advantage is a low price, but the effectiveness of this does not decrease. The popularity of the product is due to its natural composition with the addition of animal bile. In addition, "Allolokh" improves the digestive process as a whole.

"Odeston" is also popular, despite the fact that it belongs to the category of synthetic products. Its active substance is gimekromon, which acts on the mechanism of bile ejection. Prevents the formation of stones in the bladder. But you should be careful when using it, since the drug has a number of contraindications.

But Flaming is the idol of those who prefer natural and herbal preparations based on various herbs. Its advantage is that it acts in several directions at once: it improves the production of bile, tones the gall bladder, eliminates spasms in the ducts, is able to thin the secret, and has an antibacterial effect. Positive effect on the entire digestive system. But it has some contraindications, which are also worth considering and discussing with a specialist before starting therapy.

Any of the above choleretic drugs can normalize the outflow of secretion and the activity of the gallbladder as a whole. But will this effect last only? There is already how lucky. Do not heal, hoping for a chance! If you find yourself symptoms that indicate stagnation of bile, rather, contact a medical institution for timely and professional help.