The drug "Regulax" is available in the form of fruit cubes, as well as a colorless transparent solution. The medicine belongs to the pharmacotherapeutic group of laxatives. The active component (in solution) is sodium picosulfate monohydrate . Additional substances: sorbitol solution seventy percent, distilled water, propylene glycol.
The drug "Regulax Picosulfate" (reviews of experts indicate this) begins to act ten to twelve hours after use. The active form of the drug, formed by hydrolysis under the influence of the activity of intestinal microorganisms, has an exciting effect on the nerve structures in the intestinal wall. As a result of this process, the progress of the contents is accelerated, and the absorption of water and electrolytes is reduced. The medicine "Regulax" (drops), reviews of doctors confirm this, after oral administration it is not exposed to absorption and liver-intestinal circulation.
The drug is indicated for atonic constipation. The medicine "Regulax" (patient reviews confirm this) contributes to the effective regulation of stool with cracks in the anus, proctitis, hemorrhoids. The medication is used in preparation for operations, radiological and instrumental studies.
The medicine "Regulax" (reviews of experts are united in this) should not be used for intestinal obstruction, hypersensitivity, strangulated hernia. Contraindications include peritonitis, inflammation of the acute course in the organs in the abdominal cavity, with abdominal pain (unexplained nature). The drug "Regulax" is not prescribed for bleeding from the digestive tract, cystitis, metrorrhagia, severe dehydration. Contraindicated in case of spastic constipation, in the first trimester of pregnancy. The medicine is not prescribed for children under four years of age.
The drug "Regulax" (reviews of doctors indicate this) is most advisable to take at night once a day. For adults, the initial dose is thirteen drops, with persistent constipation - twenty-six. For children, the recommended dosage is five to eight drops. In accordance with the obtained therapeutic effect, the amount of the drug is reduced or increased.
During lactation, the drug is taken with caution.
When using the drug “Regulax”, dehydration, diarrhea, and abdominal pain are likely to occur . In some cases, there may be a disturbance in the water-electrolyte balance, a decrease in blood pressure, weakness, and a convulsive state.
With the simultaneous use of cardiac glycosides and Regulax medication (expert reviews confirm this), an increase in sensitivity to the former is possible.
The combined use of the drug with glucocorticosteroids and diuretics may increase the risk of electrolyte disturbances.
The laxative effect of the drug "Regulax" can reduce antibiotic drugs.
In case of an overdose, an increase in adverse reactions is likely. Along with this, it is noted (with chronic overdose against the background of prolonged use) ischemia of the mucosa in the large intestine, damage to the renal tubules. Probably the development of urolithiasis, secondary hyperaldosteronism.
As a treatment, correction of water-electrolyte balance disorders and gastric lavage are used. Spasmolytic drugs are indicated.
Specialists note that the use of the drug "Regulax" is advisable only when other means (diet correction, taking drugs that increase the volume of intestinal contents) did not give a therapeutic result.
Before using the medication, you must consult your doctor.