Povidone - what is it? You will find the answer to this question in this article. It will also provide information about what features the substance mentioned has, as well as drugs based on it.
general information
Do you know what a substance like povidone is? What it is? According to experts, the substance is a component of many drugs. It is an insoluble form of low molecular weight polyvinylpyrrolidone, which has cross-links. In medicine, povidone is used as an enterosorbent.
pharmachologic effect
What is povidone used for? What is it and what properties does it possess? This substance has a detoxifying effect, which consists in its ability to actively bind toxins that are in the human body and come from outside, and then bring them out through the intestines. This element does not enter the systemic circulation.
As medical practice shows, povidone is not able to damage the mucous membranes of the digestive tract, as well as accumulate in the human body. Moreover, it practically has no side effects and contraindications, being a completely safe remedy.
The therapeutic effect after taking this substance appears in hours.
It should also be noted that povidone is able to slow down the rate and reduce the degree of absorption of other drugs from the gastrointestinal tract. In this regard, it must be taken after two hours after eating and other drugs.
Indications povidone
Now you know the answer to the question: "Povidone - what is it?" The considered drug is very often used for toxic forms of acute infectious diseases of the gastrointestinal tract (for example, dysentery, salmonellosis and others), food toxicoinfection (food poisoning) and intoxication (poisoning) of a different origin.
In addition, this substance is used for enteritis (inflammation of the small intestine), exacerbation of chronic enterocolitis (inflammation of the colon and small intestine), as well as liver failure.
Iodine preparations
As mentioned above, povidone is often used as the main or auxiliary component of various drugs. And iodine preparations are no exception.
"Povidone-iodine" is available in the form of a 10% and 7.5% solution for external use with the formation of foam. It should also be noted that the said tool is often used for the preparation of medicinal ointments and suppositories.
Composition, description and packaging of the solution and candles
What elements does the medicine "Povidone-iodine" include? The instruction states that the composition of this drug includes iodine in the form of a complex with polyvinylpyrrolidone binding it, as well as auxiliary ingredients in the form of nonoxynol, disodium hydrogen phosphate 12-hydrate, glycerol, citric acid, sodium hydroxide and demineralized water.
On sale, such a liquid of a dark brown color with a pronounced smell of iodine comes in plastic bottles or cans. When shaking, it foams well.
You can also purchase suppositories "Povidone". Vaginal suppositories are available in blister packs.
Features of medicines
The considered drugs have disinfectant and antiseptic properties.
The solution "Povidone-iodine" is a medication of a wide spectrum of antimicrobial action. It adversely affects most gram-negative and gram-positive bacteria. It should also be noted that the effect of this agent is longer than inorganic iodine.
Suppositories "Povidon", the price of which is about 480 rubles, are created on a water-soluble basis. Therefore, in the process of their use, the patient almost never causes irritating reactions.
It should be noted that the local use of this drug does not cause the absorption of iodine.
Indications
Why use a 10% solution of "Povidone"? The instruction reports the following indications of this remedy:
- infectious wounds in burn, surgical, dental and traumatological practice;
- trophic ulcers, bedsores and diabetic feet ;
- bacterial, fungal and viral skin infections, as well as superinfection in dermatology;
- disinfection of the skin near the probes, catheters and drains, as well as the mouth in dental practice;
- disinfection of mucous membranes and skin before surgery or invasive studies;
- disinfection of the birth canal.
7.5% solution recommended:
- with hand disinfection by medical personnel;
- disinfecting patients before surgery;
- hygienic processing of hands after contact with infected patients;
- hygienic treatment of patients;
- medical tooling, etc.
As for suppositories, they are used to treat:
- trichomoniasis;
- candidiasis;
- vaginitis;
- genital herpes.
Contraindications
Any form of the drug presented is prohibited to use:
- with hyperthyroidism;
- hypersensitivity;
- herpetiform dermatitis of Dühring;
- under the age of eight;
- lactation;
- combined use of radioactive iodine ;
- pregnancy.
Application methods
The solution "Povidone-iodine" is intended for local use. It is undiluted used for washing and lubricating infected areas of the mucous membranes and skin. If necessary, use a bandage previously soaked in the drug.
If this medication is intended for drainage systems, then it is recommended to pre-dilute it 10-100 times.
Suppositories "Povidone-iodine" is prescribed for deep intravaginal administration. The dose of this drug, the therapeutic regimen and the duration of its use are established individually only by a gynecologist.
Typically, the daily dosage of suppositories in the treatment of acute vaginitis is 1-2 pieces. In the treatment of subacute or chronic vaginitis, the drug is recommended to be used in the amount of one suppository at bedtime.
Therapy with this drug can last for 1-2 weeks.
Side effects
The use of this tool on extensive wound surfaces can lead to systemic absorption of iodine, which will necessarily affect the activity tests of the thyroid gland, and also lead to the development of neutropenia.
In rare cases, the presence of hypersensitivity to the medication can cause the patient to have allergic reactions to iodine, which manifest as hyperemia, burning, swelling, itching and pain. This requires immediate drug withdrawal.
Long-term use of “Povidone-iodine” (more than one week) can cause the development of iodism, increased salivation, swelling of the eyes or larynx.