Panangin is a combination preparation containing magnesium and potassium salts. This drug actively regulates metabolic reactions and electrolyte balance, restores metabolic processes, has an antiarrhythmic effect, and normalizes metabolism in the myocardium. Due to this property, the Panangin preparation has found application in the treatment of the cardiovascular system and associated diseases.
The mechanism of action of the drug
The complex intake of magnesium, potassium, calcium and sodium ions in the cells and in the extracellular space ensures the normal functioning of the heart muscle. If the body has a metabolic disorder and there is a deficiency of magnesium and potassium ions inside the cells of the heart muscle, this can lead to disturbances in the rhythm of cardiac activity, to an increase in blood pressure, metabolic disturbance in the myocardium, to the development of IHD, as well as to an increase in cardiac toxicity drugs - glycosides.
Taking the drug "Panangin" gives the body an additional opportunity to receive magnesium ions for their participation in protein synthesis and for obtaining additional energy from carbohydrates. The normal content of magnesium ions in the cells of the heart muscle allows the heart muscle to contract less frequently. This leads to a decrease in oxygen demand, to reduce angina attacks. Under the influence of a magnesium ion, an expansion of small blood vessels and an increase in blood flow occur. Magnesium and potassium ions are vital for the functionality of the heart muscle, the mechanism of action of the Panangin preparation is based on this. Contraindications to taking the drug are based on the activity of magnesium and potassium ions. With a large number of this drug can not be taken.
For the treatment of heart diseases and in case of insufficient content of magnesium and potassium salts in food, the patient is prescribed Panangin. Indeed, as the main enzymes, these salts take part in the biochemical reaction of metabolism in the patient's body.
How to take Panangin?
The medication in the form of tablets is made three times a day, two tablets. Preventive therapy is carried out one tablet three times a day. The course of treatment lasts 3-4 weeks. Intravenously, the Panangin medicine is administered in the form of a solution drip at a rate of 20-25 drops per minute once or twice a day, 300 ml each.
Pananginum: contraindications
Contraindications for the use of the drug are:
- myasthenia gravis,
- severe kidney disease with impaired function,
- high content of magnesium and potassium in the body,
- heart block
hemolytic anemia
- adrenal insufficiency,
- severe course of any disease,
- shock.
Panangin, the contraindications for use of which apply to pregnancy and breastfeeding, are prescribed to women of childbearing age with caution.
It is not recommended to use the Panangin medicine during the period of use of drugs that contribute to the retention of potassium and magnesium in the body.
Contraindications to its use apply to patients with intolerance to sorbitol, fructose. In case of impaired amino acid metabolism, exicosis, hemolysis, dehydration, and pathology of the renal system, the use of this drug is not recommended.
The drug "Panangin": side effects
Deterioration of the intestinal mucosa, epigastric pain, bleeding from the digestive system, diarrhea, decreased blood pressure, dry mouth, nausea, skin itching, thrombosis, dizziness, sweating, asthenia - all these diseases can become side effects when using the Panangin medication ". The appearance of hypermagnesemia and hirpkalemia can provoke a rapid infusion of the drug intravenously.
With an overdose of the drug, cardiac arrest, paresthesia of the extremities, a change in the indications on the electrocardiogram can occur. In this case, urgent use of dextrose or sodium chloride is required, intravenous and urgent medical attention. In an emergency, hemodialysis and dialysis are used.