If the doctor has prescribed Biseptolum, the patient is probably interested to know what are the features of this drug. Even before the start of use, it is recommended to find out in detail the nuances of the effectiveness of the drug. It is necessary not only to know the rules of admission and indications, but also to be guided in contraindications, side effects. "Biseptolum" has a number of restrictions for use. All of them are given in the instructions that accompany the pharmaceutical product.
general information
"Biseptolum" is similar to co-trimoxazole, is its trade name. This is a fairly popular antibacterial drug, often prescribed for both children and adults. It is used if the microflora that provoked the disease is susceptible to this remedy. The list of bacteria destroyed by Biseptolum is quite large. True, it is impossible to prescribe this drug to everyone. First, the doctor will check if there are any contraindications. Side effects of Biseptol are more likely to occur if you do not take into account the list of restrictions. However, this is not so difficult, fortunately, each pack is accompanied by an instruction, which gives a complete list of conditions.
Indications and contraindications of Biseptol are due to the peculiarities of its effect on micro- and macroorganisms. The tool shows a pronounced effect in the event that a person is infected with microscopic negative and positive, when studied by Gram, life forms. It is made in tablet form, available in two dosage options: 120 and 480 mg. Each tablet contains trimethoprim, sulfamethoxazole. For 20 mg of the first, 0.1 g of the second is added, for 80 mg of the first - 0.4 g of the second.
"Biseptolum" is also made in the form of injections (solution for injective administration). In pharmacies, the medicine is sold only upon presentation of a prescription by the attending physician. As noted in the reviews, the medication is more than affordable.
Strictly impossible!
When prescribing a medicine, the doctor will necessarily inform the patient about contraindications for the use of Biseptolum. If the patient's condition includes any of the conditions, the medication is not prescribed. The safety of the therapeutic program depends on this. Since it is often difficult for an average person to determine how much the restrictions apply to him personally, one cannot use the medicine without permission.
Among the main contraindications to the use of "Biseptolum" are renal lesions affecting the parenchyma. If this condition is confirmed, you can not use the medication in any case.
Among the contraindications of Biseptolum for women, men, and children are significant renal impairment. This applies to a situation where it is not possible to control how high the content of the active ingredient in the blood serum is.
For women, children, men contraindications "Biseptolum" include kidney failure. The restriction applies to a severe form of the disease. Such is considered the condition of the body, accompanied by creatinine clearance of less than 15 units.
Limitations: more details
The list of contraindications "Biseptolum" for boys, girls, adults includes severe blood diseases. These include various forms of anemia, including a condition caused by folic acid deficiency. The list includes agranulocytosis and leukopenia.
Among the contraindications of Biseptol relevant to children, hyperbilirubinemia is worth noting. You can not prescribe a drug if the body experiences a lack of glucose-6-phosphate dehydrogenase. Neglect of this condition is associated with the risk of hemolysis.
Contraindication of Biseptolum, connected with reproductive function, is very important. Nursing mothers, women bearing a child, this pharmaceutical product is not prescribed. Pregnancy, lactation are considered important limiting factors for taking many drugs, including the antimicrobial drug in question.
Among the contraindications "Biseptolum" should be noted young age. For example, a tablet is not used for children under three years of age.
You can not prescribe a drug if the patient's body is excessively sensitive to the main, auxiliary ingredients of the drug. It is forbidden to take "Biseptolum" against the background of increased susceptibility, sensitization reactions due to the production of sulfonamides.
"Biseptolum": curious information
Not every modern person understands what class of drugs Biseptol belongs to. This information seems to many no less significant than a list of restrictions on use, contraindications. Biseptol is a pharmaceutical product containing sulfamethoxazole. It is a synthetic substance effective against bacteria. It belongs to the sulfonamide group. The second ingredient is trimethoprim. This is a bacteriostatic component. Mutually, these two substances activate each other. As experience has shown, the combined use of these two ingredients allows you to achieve a particularly stable, strong, fast effect.
Frightening others with its list of contraindications, Biseptol is not one of the pure antibiotics. One of its components is an antibiotic, the second ingredient has an effect similar to this group, but not ranked as one. In general, the effectiveness of the drug is similar to that characteristic of classical antibiotics.
How it works?
So that pathological life forms can actively multiply, they need para-aminobenzoic acid. Its chemical structure has a number of features that make it possible to speak of similarities with sulfamethoxazole molecules. When an antibiotic enters the patient’s body, it reacts at the cellular level, replacing para-aminobenzoic acid for the microbe. Thanks to such a substitution, further reproduction of the pathological form of life is blocked. Trimethoprim, in turn, inhibits folic acid activity. Bacteria cannot exist without this substance, respectively, vital activity is inhibited.
When prescribing a medicine, it is necessary to take into account not only Biseptol's contraindications, but also a list of pathological microorganisms against which the drug is effective against infection. If in a particular case a person is sick due to infection with forms for which the active ingredients of Biseptol are not scary, taking this remedy will not do anything good, but it will provoke side effects. In the instructions, the manufacturer indicates the effectiveness of the use of tablets, syrup, and the administration of Biseptol injections in case of invasion of strepto-, staphylococcus, E. coli. You can use the medication in the fight against chlamydia. It is prescribed if the tests showed Shigella, Klebsiella, Legionella. Indication for use is infection with cholera vibrios. Biseptol is effective against salmonella and is used in the fight against mycobacteria. A good effect is given by the treatment with plasmodia, toxoplasma, dangerous fungal microorganisms with such a medication.
Will it help or not?
Studies show that in recent years, cases of resistance of pathological microorganisms to the active components of Biseptol have become more frequent. This is especially noticeable when analyzing the results of using a pharmaceutical product to combat staphylococcus aureus, streptococcus. If the tests show just such forms of pathological life, it is possible to choose an alternative therapy option, it is advised to abandon the composition in question. The reason is not Biseptol's contraindications, but the fact that treatment may not be effective. It is often difficult even for an experienced doctor to predict in advance how reliable the use of tablets in a particular case will be.
"Biseptol" is not prescribed if the disease is caused by life forms that provoke syphilis, tuberculosis. The tool does not help against leptospirosis.
What do people say?
In specialized magazines, in the vast expanses of resources devoted to aggregating user opinions, one can find a lot of feedback on the use of Biseptol in various forms of release. More often there are positive opinions, people talk about the fact that the drug product helped, allowed to get rid of the disease in a short time. There are also reviews about the side effects of Biseptol. There are relatively few of them. The main percentage tolerates the use of the drug well. This is proved by scientific research, statistical information. This is also evidenced by the responses. People who said that they were worried about adverse events during the course recognized that they passed quickly, were relatively light, and practically did not worsen the quality of life of the patient.
When is it worth?
Injections, syrup, Biseptol tablets are prescribed if bronchitis is diagnosed. The medicine is prescribed for the treatment of pleurisy, with pulmonary inflammation. Biseptol has established itself as a reliable tool in the fight against otitis media and sinusitis. It is also used in the presence of foci of inflammation in different parts of the respiratory system, including sinusitis. Among the indications are pharyngitis, laryngitis. The appointment of "Biseptolum" for intestinal infection is justified and reasonable. If cholera is diagnosed, if a person suffers from dysentery, the drug in question will help him. It is used in the fight against typhoid, for the treatment of gastritis, paratyphoid. You can prescribe "Biseptolum" for enterocolitis and inflammation of the pancreas.
"Biseptolum" is indicated for sexually transmitted diseases, infection of the genitourinary system. The medicine is used against the background of gonorrhea, inflammation of the urethra, with prostatitis, salpingitis. The medication is recommended for wounds, skin inflammatory pathologies. It is prescribed for a number of infectious diseases caused by invasion of pathological bacteria. For example, Biseptol has proven itself in the fight against meningitis and toxoplasmosis.
Often it is they who resort to it when malaria is diagnosed. The drug reliably treats brucellosis and is used in the fight against scarlet fever.
Unwanted effects
Taking medications is always associated with the risk of unwanted side effects. Contraindications "Biseptolum", for example, significantly exceed the obvious benefits of treatment, therefore, exclude the use of the drug. If there are no contraindications to the case, taking the remedy may also be accompanied by negative reactions. The manufacturer indicates exactly what is possible in the instructions that accompany the pharmaceutical product. The probability of different responses of the body can be found in the responses of those who took it.
As you can conclude from the reviews, the side effects of Biseptol are relatively rare, and if there are, then most are limited to unpleasant phenomena from the gastrointestinal tract. During treatment, others complain of loose stools and abdominal pain. Tests have shown that all adverse reactions during treatment with Biseptolum are easily tolerated by patients and soon pass.
The drug can provoke a depressed state. Some were sick, dizzy. The active ingredient inhibits the activity of E. coli, therefore, against the background of treatment, there is a possibility of a decrease in the concentration of vitamins generated in the digestive tract.
How to use correctly?
For Biseptol to help, you need to take the medicine correctly. The dose is determined by the doctor, starting from the diagnosis, the age of the patient, his weight, as well as the characteristics of the case.
Persons over 12 years of age are usually prescribed a pair of larger dosage tablets to be taken twice daily. Accordingly, the patient receives 1920 mg of active compounds per day. Between receptions it is necessary to observe strictly 12-hour pauses. The duration of treatment varies from five days to two weeks. In case of need for a long course, the dose is halved.
Children from two years of age to five years should receive 0.24 g of the drug twice a day. For children older, the optimal dose is 480 mg twice daily.
Persons under two years of age are prescribed only Biseptolum in liquid form. A single dose for those over the age of twelve is 20 ml. 2.5 ml is prescribed for children from three months to six months of age, twice as much for persons under three years of age, and 10 ml for children from four years of age.
Biseptolum is used twice a day. It is advisable to use a medicinal product after a meal. Means abundantly washed down with water without additional additives.
Mutual influence
The effectiveness of treatment with Biseptol is slightly reduced if a person receives an abundance of protein with food. For the entire period of therapy, if possible, the diet should be reviewed in order to reduce the amount of such food. The effectiveness of the drug program is reduced if the diet is enriched with products in which there is a lot of para-aminobenzoic acid. These include tomatoes, beans, herbs, carrots, and some varieties of cabbage.
Milk destroys the active ingredients of the drug. The combination of Biseptol and alcohol increases the risk of allergies.
"Biseptol" can not be combined with a number of commonly used drugs. The drug is not used simultaneously with thiazide diuretics and in combination with Aspirin. It can not be taken at the same time as Butadion. It is forbidden to combine the considered antimicrobial composition and Naproxen. Under the influence of Biseptol, the effectiveness of Warfarin is growing, and the effects of drugs prescribed for the treatment of diabetic diseases are becoming stronger. But tricyclic antidepressants, on the contrary, are becoming weaker.
Is there an alternative?
Generics "Biseptolum" are medicinal formulations in which the same active components are present. These are Apo-Sulfatrim and Bactecode. The Bactrim and Bactoreduct medicines belong to the same category. However, among all of the above, it is easiest to buy Biseptol in a pharmacy, since it is sold almost everywhere and is quite cheap: less than a hundred rubles per package, which is enough for one course.
There are many medications that, like Biseptol, belong to the class of combined antibacterials, but differ from the considered composition in their active ingredients. The Biseptol analogues in the group will be Levomethyl and Levosin. This also includes the relatively popular drugs "Ingalipt", "Ingalipt-N."
To summarize
As can be concluded from the above, with proper use, Biseptolum is a reliable tool, effective in a wide range of diseases. The medication is capable of provoking side effects, especially if the contraindications mentioned by the manufacturer are not observed. The list of restrictions for use is relatively wide, so you can not appoint Biseptol yourself, you can not take into account any important condition.