The drug “Ebrantil” defines the instructions for use as an antihypertensive agent with a central and peripheral effect. The main component of the drug - urapidil - acts on the vasomotor center, reduces peripheral vascular resistance, resulting in reduced diastolic and systolic blood pressure. Moreover, the Ebrantil medicine practically does not change the heart rate and cardiac output.
Indications for use
In the form of a solution intended for parenteral use, the drug is prescribed for patients with hypertensive crisis, arterial hypertension (refractory, severe). In order to lower blood pressure before and after surgical interventions, Ebrantil injection solution is also used. Tablets - a dosage form that is not typical for this medication, but Ebrantil capsules are produced, which are indicated for use in case of arterial hypertension.
Release form and composition
As already noted, the production of the drug is carried out in the form of capsules (in bottles of 50, 100 units) and a solution for injection (in ampoules of 5, 10 ml). One capsule contains 30 or 60 mg of urapidil, and 1 ml of solution - 5 mg.
The method of using the "Ebrantil"
Instructions for use show the capsules to be taken with food inside, swallow whole and drink with a small amount of liquid. To achieve constant control of blood pressure, you need to drink the medicine at regular intervals. The dose is set by the doctor. For a gradual decrease in blood pressure, as a rule, a medication “Ebrantil” is prescribed (instructions for use include this information) in an amount of 30 mg twice a day. If there is a need for an early onset of the therapeutic effect, the dose is increased to 60 mg. Maximum per day is allowed to use 180 mg of the drug. The Ebrantil solution (instructions for use indicates that the doctor selects the dosage of injections) is administered intravenously, it is also possible to carry out continuous and continuous infusions. In the parenteral form, the medicine is allowed to be used for a week, then you should go to the medication orally or choose another antihypertensive drug.
Side effects
It is extremely rare in the course of therapy that negative effects develop. In isolated situations, the appearance of such undesirable phenomena as thrombocytopenia, cardiac arrhythmias, angina pectoris, a strong decrease in blood pressure, orthostatic hypotension was noted . There is also a risk of nausea, diarrhea, dry mouth, dizziness, high fatigue, sleep disturbances, headaches, and causeless anxiety. Allergic reactions may develop: erythema, urticaria, anaphylactic shock.
Contraindications
Means "Ebrantil" is not prescribed for people with intolerance included in the ingredients, as well as patients with galactosemia, lactase deficiency. Injection solution is not used to treat patients with aortic stenosis. In pediatric practice, the medication is not used.