The drug "Pimafucin" (ointment, tablets, suppositories) belongs to the category of antifungal polyene antibiotics of the macrolide group. The drug has a wide range of effects. The medicine has a fungicidal effect. The active component of natamycin binds sterols in the cell membrane of the fungus. As a result, the integrity of the wall function is violated. This, in turn, leads to the death of the pathogen. Most Pimafucin medications (ointment, tablets, suppositories) are sensitive to most pathogenic yeast fungi, especially the Candida genus. Less effective drug for dermatophytes. In clinical practice, there is no drug resistance. Against the background of oral administration, the drug is practically not absorbed. When applied externally, absorption is also almost not observed. In this regard, the drug does not have a systemic effect.
The drug "Pimafucin" (ointment, tablets, suppositories): indications
In tablet form, the medicine is used for the prevention and treatment of candidiasis in the intestine, including after receiving cytostatics, antibiotics, corticosteroids. The drug "Pimafucin" (ointment), the instruction recommends for fungal infections of the skin and mucous membranes, provoked by pathogens that are sensitive to the drug. Indications include balanpostitis, vulvovaginitis, vulvitis, vaginitis, pathology due to the activity of Candida fungi, candidiasis of nails and skin. The drug is recommended for external otitis media, provoked (primarily) by fungi or complicated by candidiasis. Dermatomycoses are also referred to as indications. Suppositories are prescribed for vulvovaginitis, vulvitis, vaginitis due to Candida fungi.
The drug "Pimafucin" (ointment, tablets, suppositories): method of use
Inside with intestinal candidiasis , a tablet (100 mg) is prescribed 4 p. per day. Duration of use is an average week. For children, the dosage is the same, the frequency of use is 2 p. in a day. The drug "Pimafucin" (ointment) is applied to the affected areas no more than four times during the day. With mycoses in the external auditory canal before use, the affected area is cleaned and dried. After applying the medicine, a cotton swab is placed in the ear. Suppositories are assigned 1 pc. for three to six days. The introduction is carried out in a horizontal position. It is advisable to use the drug in the evening (at night). Depending on the course of vaginitis, a specialist may prescribe an additional oral dose. The dosage in this case is 1 tablet 4 r. in a day. The duration of treatment is 10-20 days. After eliminating the symptoms, it is recommended to continue therapy for several days to consolidate the effect.
Means "Pimafucin": price
Ointment costs a little over 500 rubles in pharmacies.
Adverse reactions
Against the background of treatment, mild irritation, diarrhea, and nausea are likely. When using the ointment, a burning sensation is possible. With an increase in negative reactions, you need to visit a doctor, stopping the use of the medicine.