Chimotrypsin is a proteolytic enzyme. When used locally, the pharmacological effect is manifested in the cleavage of dead (necrotic) tissues and fibrinous formations (blood clots, blood clots). The drug helps to liquefy viscous secrets, exudates. Means "Chymotrypsin" (instructions for use indicates this) is a powder or shiny white flakes. It is diluted with water or sodium chloride (isotonic solution).
Structure
The medication "Chymotrypsin" (instructions for use contains such information) is obtained from the pancreas of cattle. The active substance in the juice of the gland is present in an inactive form in the form of chymotrypsinogen. Under the influence of trypsin, its activation occurs. As a result, several forms are formed: chymotrypsins a, b, s, g, p. All of them are similar in their enzymatic properties, but differ in activity. As a medicine, a-chymotrypsin is of practical importance today. This compound, like trypsin, hydrolyzes peptones and proteins. As a result, relatively low molecular weight peptides are formed.
Appointment
The medication "Chymotrypsin" recommends the use of thrombophlebitis (inflammatory processes in the venous walls and clogged vessels), osteomyelitis, sinusitis. Indications include otitis media, iritis, tracheitis. A medication is prescribed for patients with inflammatory-dystrophic forms of periodontal disease, iridocyclitis, bronchitis.
Medication "Chymotrypsin". Instructions for use. Price
The medicine is administered intramuscularly. Dosage for adults - daily at 0.0025 g once. Immediately before injection, crystalline chymotrypsin in an amount of 0.005 g is dissolved in 1-2 milliliters of sodium chloride (isotonic solution) or novocaine (0.5-2% concentration). The introduction is carried out deep into the gluteus maximus muscle in the upper outer quadrant. For one course, 6-15 injections are calculated. The cost of the drug is within 500 rubles.
Contraindications
Means "Chymotrypsin" instructions for use prohibits the appointment of decaying tumors of a malignant nature, bleeding wounds. Contraindications include hypersensitivity. The tool is not intended for intravenous administration. The advisability of prescribing the medication to pregnant or lactating patients is determined by the doctor.
Side effects of chymotrypsin. Patient reviews. Storage rules
After insertion into the muscle, some patients complain of burning sensations and allergic skin reactions at the injection site. In some cases, patients consulted doctors in connection with the development of bleeding from healing (granulating areas). In general, people who have undergone therapy note that the drug is well tolerated. In practice, no cases of overdose have been recorded. Experts recommend consulting a doctor before use. Store the product at a temperature of no more than 10 degrees in a dark place.