In the article, we will consider how to use Indomethacin suppositories for hemorrhoids.
Suppositories are non-steroidal anti-inflammatory drugs that are often used in the treatment of hemorrhoids. This disease is often accompanied by severe soreness, the development of an inflammatory process that inhibits recovery. In such cases, it is necessary to give preference to drugs that can stop the manifestations of the disease.
Suppositories "Indomethacin" with hemorrhoids are highly effective in the treatment of this pathology. The use of suppositories can slow down the formation of nodes, prevent the appearance of cracks in the rectum. Quite often, experts recommend taking Indomethacin capsules in parallel with suppositories, which helps to enhance the effect.
Structure
The active substance in the composition of the drug is indomethacin. Suppositories may contain 50 or 100 mg of the active ingredient.
The ingredients of the drug are selected in such a way that the suppository, after introduction into the rectum, quickly dissolves and is absorbed into the tissues of the anus and hemorrhoids, due to which the anti-inflammatory effect develops in a short period of time. In addition, the effect of anesthesia is provided.
The preparation also contains potato starch and fat, which are auxiliary substances that improve the absorption of the main component. Candles are cylindrical, which facilitates the process of their introduction into the rectum.
Suppositories "Indomethacin" with hemorrhoids can be used in cases where the hemorrhoidal nodes have internal localization. With external hemorrhoids, it will be advisable to use ointment and gel forms of the drug - the principle of their effect is similar to that of suppositories. In some situations, the use of tablets is indicated.
Many people wonder if Indomethacin suppositories can be used for hemorrhoids?
Pharmacological effects
Any drugs containing indomethacin exhibit high antipyretic and anti-inflammatory properties. Under the influence of the medication, the secretion of exudate is suppressed - the fluid secreted by the tissues during the inflammatory process.
Against the background of the use of the drug, the severity of the pain syndrome decreases, swelling decreases, and the body's recovery after surgery is accelerated. In the case when hemorrhoids are accompanied by the appearance of regular pains, the drug allows you to quickly stop it.
After getting into the rectum, the candles melt, as a result of which the active component is released, which is quickly absorbed into the surrounding tissue and then gets into the blood. Indomethacin acts on the vascular walls, thereby preventing the occurrence of blood clots. Against the background of the action of the active substance, there is an increase in the outflow of lymph from the affected areas, and the severity of inflammation is reduced.
As part of complex therapy
The use of Indomethacin suppositories is advisable as an element of complex therapy in parallel with antimicrobial drugs. They allow you to suspend inflammation, lower body temperature. The active substance is metabolized in the tissues of the liver, about 70% of it is excreted by the kidneys, the rest - through the intestines.
Indomethacin-based drugs can be used in the treatment of not only hemorrhoids, but also other pathologies.
Below you will find detailed instructions for use for suppositories "Indomethacin" for hemorrhoids.
Indications for use
Indomethacin drugs are recommended for patients if there is a need to stop acute manifestations of pathology. The doctor must choose the necessary medications. The main indications for the use of the drug are:
- Diseases of the musculoskeletal system.
- Inflammatory processes in the peripheral nerves.
- Ophthalmic surgery.
- Violations of the reproductive system.
- ENT infection.
- Chronic, acute form of hemorrhoids.
- Disorders of the genitourinary system, cystitis, prostatitis.
Therapy with the use of Indomethacin suppositories from hemorrhoids helps to alleviate the patient’s condition, reduce the severity of pain in the anal region, rectal zone. The medication helps to eliminate the discomfort that occurs during movements. The patient gains the ability to sit normally without feeling sharp pain. The inflammatory process stops, the disease recedes.
When using rectal suppositories, it is important to follow the recommendations indicated in the instructions for use - this will allow you to cure hemorrhoids in less than a month.
The use of indomethacin suppositories in the treatment of hemorrhoids
What else does the instruction for Indomethacin suppositories for hemorrhoids tell us?
The duration of therapy and the required dosage should be determined by the doctor, taking into account whether the patient is using any other medicines, as well as the features of the appearance and course of the pathology.
It is important to select drugs so that their effects are consistent. In this case, it becomes possible to obtain the greatest efficiency, and the negative effect of the drug components on the body can be avoided.
For hemorrhoids, Indomethacin suppositories are prescribed in standard dosages: suppositories are indicated to be used one at a time twice a day.
When purchasing rectal suppositories based on indomethacin, the dosage of the drug should be taken into account, since the active component in each suppository can be contained in the amount of 100 mg and 50 mg. With a small dosage, doctors recommend introducing suppositories rectally three times a day, with an increased dosage, once or twice a day. Take more than 200 mg of indomethacin per day. If the candle has a dosage of 100 mg, it is more advisable to use it before bedtime.
When treating patients younger than 14 days, it is necessary to first calculate the dosage according to the rule 2.5 mg / kg. The duration of therapy is usually about 7 days.
Use in the lactation period, during pregnancy
One of the main contraindications to the use of suppositories based on indomethacin is pregnancy. The liver is involved in the metabolism of the drug, for which such a process can be an overload. At the same time, the likelihood of the components of the drug getting into the blood of the fetus is very high.
In the lactation period, the drug should not be used. If necessary, the woman should first stop natural feeding. With lactation, it is recommended to give preference to drugs with a more gentle effect.
Contraindications
Indomethacin should not be used in the following cases:
- With pathological changes in the liver, kidneys, since it is these organs that are involved in the excretion of most of the active components of the drug.
- With aspirin asthma. The use of non-steroidal drugs against inflammation can trigger an exacerbation of the present disease.
- CCC diseases. When using drugs based on indomethacin, the risk of jumps in blood pressure and the appearance of disturbances in the activity of CVS increases.
- In old age, at work requiring increased attention.
- In the implementation of vehicle management.
Negative impact
It is recommended to familiarize yourself with the negative effects of the drug in advance. They do not depend on the manufacturer producing the medication and the pharmacological form of the drug. Against the background of the use of indomethacin, a violation of the functions of the gastrointestinal tract can be observed. There is a possibility of occurrence:
- Soreness in the peritoneum.
- Impaired appetite.
- The development of heartburn during meals, after it.
- Flatulence.
- Diarrhea.
- Nausea, vomiting, bitter taste in mouth.
In some cases, negative effects due to neurological disorders are noted. These include dizziness, drowsiness, unjustified irritability, fatigue, headaches. In addition, there may be disturbances in the activity of the kidneys, an increase in the level of protein in urine samples.
With regular use of the drug in amounts exceeding the norm, there is a risk of a marked increase in blood pressure. In addition, indomethacin medications can cause disturbances in the sensory organs. The patient may develop conjunctivitis, tinnitus, hearing impairment, taste perception. When applied topically, allergic manifestations on the mucous membranes are not ruled out.
The appearance of a minor allergic reaction in the form of a rash that does not cause discomfort is not an indication for drug withdrawal. However, with more pronounced reactions, you should refuse to use the medicine and consult with a specialist regarding the replacement of therapeutic agents. In the absence of a proper reaction to negative manifestations, serious consequences can occur, for example, anaphylactic shock, acute intoxication.
Interaction with other drugs
Long-term use of drugs containing indomethacin may cause a decrease in the effectiveness of antihypertensive, uricosuric, and diuretic drugs. When using suppositories, the effect of anticoagulants, antiplatelet agents, fibrinolytics is enhanced. When combined with some drugs, their negative effects may increase. Unacceptable is the parallel use of indomethacin and paracetamol.
When used together with glucocorticosteroids, ethanol, colchicine, the risk of developing gastrointestinal complications and bleeding is high.
Analogs
In cases where the patient is contraindicated for any reason based on indomethacin, it is allowed to replace them with Indobene, Metindol, Indovazin, Tridocin.
Suppositories for hemorrhoids "Indomethacin Berlin-Chemie" are considered no less effective. This medication has a similar therapeutic effect. However, any replacement of the drug should be agreed with the doctor. Candles "Indomethacin Berlin-Chemie" can be purchased at any pharmacy.
Reviews
Most feedback on experience with indomethacin-based suppositories is positive. Patients note that the effect of the drug develops rapidly, allowing you to stop acute pain and inflammation, negative effects do not occur often. In addition, the drug is available as it has a fairly low cost.
It is better to familiarize yourself with the reviews about Indomethacin suppositories from hemorrhoids in advance.