In the article, we consider the instructions and reviews for the Proginova drug.
The lack of estrogen, that is, female hormones, is extremely negative for the reproductive system. Hormone deficiency contributes to a significant deterioration in well-being and often leads to infertility. In order to quickly replenish estrogen levels and restore normal ovarian function, doctors recommend taking effective hormonal medicines, one of which is a French drug called Proginova.
Product Description
According to the instructions, “Proginova” helps to replenish low estrogen levels during menopause, as well as after removal of the ovaries, preventing a decrease in bone mass. This drug produces a feminizing effect on the body. This tool is able to have anti-atherosclerotic and procoagulant effects. "Proginova" contains esteradiol valerate, which in the female body turns into natural estradiol.
This medication is often used when planning pregnancy, and in addition, with IVF. The instruction to "Proginova" reports that against the background of using the product, there is no suppression of ovulation and almost no change in hormonal production in the body itself. In addition, the use of this hormonal drug, and then its abolition contribute to the exit of the egg follicle, which significantly increases the woman's chances of successful and speedy fertilization.
The drug "Proginova" can eliminate estrogen-deficient symptoms in the form of hot flashes, sweating, sensations of heat or cold. Also, thanks to this medicine, it is possible to cope with manifestations in the form of chills, sleep disturbances, depression, irritability, nervousness, headaches, dizziness, atrophy of the skin and mucous membranes. In addition, this drug serves as an effective prevention of osteoporosis in women with estrogen deficiency.
Indications for use
As the instructions indicate, "Proginova" is intended for hormone replacement treatment of women in menopause, and in addition, after removal of the ovaries. The medicine can also be used to prevent postmenopausal manifestations of osteoporosis.
The cause of infertility is often a hormonal failure in the female body. Thanks to the prescription of this drug in IVF, doctors are able to increase the amount of estrogen, and in addition, stabilize the female hormonal background. At the birth of a child through this medication, labor is stimulated. The medicine "Proginova" is released in the form of a dragee, they are taken only once a day exactly twenty-four hours later.
In addition, this hormonal drug is prescribed for the treatment of cancer of the breast, prostate gland and against the background of urogenital disorder with trigonitis, urethritis, atrophic vulvovaginitis, dyspareunia, as well as in the presence of hyperandrogenemia or alopecia.
Instructions for use for treatment
In accordance with the instructions for Proginova, there are two regimens for taking this medicine:
- In a cyclic treatment regimen for three weeks, tablets are taken one daily. Then they take a break for one week. The pills are taken orally after meals and are not chewed. They are washed down with water. One dragee is taken daily for twenty days, then a break is made for a week.
- With a continuous treatment regimen for three weeks, "Proginova" take one tablet daily. When the packaging of the medicine ends, you need to start the next pack. A break in this case is not done.
A suitable regimen is chosen only by the doctor. In the event that the patient does not have the uterus removed and menstruation continues, Proginova in combination with one or another progestogen should be started in the first five days of the cycle. But patients with extremely rare menstruation, along with postmenopausal women, can start using the drug at any time, but only on condition that pregnancy is completely excluded.
The instruction to Proginov confirms this.
Application subtleties
At the beginning of hormonal treatment, it is necessary to stop the use of hormonal contraceptives. If necessary, patients should recommend non-hormonal contraceptives.
The medicine "Proginova" does not affect the ability to control the mechanisms, in this regard, women while using the drug can drive cars and engage in various activities that require reaction speed and attention. Given that this tool is a hormonal drug, it must be used exactly according to the scheme and with great care.
It is important to follow the instructions for use with Proginova.
It is strictly forbidden to spontaneously establish for yourself the duration of the treatment course along with the daily dosage of the medicine. Improper use of the product, for example, with an insufficient interval, at different times daily, can provoke headaches along with sleep disturbances, a general deterioration in well-being, spotting not during menstruation, and so on.
Side effects
The presented drug can provoke the following adverse reactions:
- The appearance of sensitivity, an increase in the size and tenderness of the mammary glands.
- The occurrence of breakthrough bleeding and amenorrhea.
- The appearance of intermenstrual spotting vaginal discharge.
- The development of menorrhagia and increased libido.
- The appearance of a tumor of the mammary glands.
Also, during the periods of treatment with the medication, all kinds of negative manifestations can be observed in the form of sleep disturbances, the appearance of severe, and at the same time, acute itching, headaches, hearing and vision disorders, increased pressure, and spotting that does not appear during menstruation is also possible. Among other things, chest pain can be observed along with a feeling of lack of air and general poor health.
Drug overdose
When an overdose of Proginova occurs in women, uterine bleeding is possible along with nausea and vomiting. In the event that the patient notices symptoms of an overdose, then she urgently needs to consult a doctor.
Contraindications
Contraindications in the case of taking the described drug are as follows:
- The presence of diabetes in a woman.
- The presence of heart and liver diseases.
- The presence of tumors of different origin.
- The development of a tendency to thrombosis and the appearance of endometriosis.
- The patient is under eighteen years old.
- Lactation period.
Why is the drug prescribed for IVF?
According to the instructions for use, Proginova for IVF is prescribed to women in need of substitution treatment. The need for the use of this drug is determined by the reproductologist. The following are the nuances of using this medication:
- Often, “Proginova” is prescribed along with ovarian stimulation during puncture. The introduction of the drug is continued during embryo transfer into the woman’s uterus. This is done before the appearance of positive tests that indicate confirmation of pregnancy. If pregnancy does not happen, then the doctor has the right to stop taking this medicine.
- After reaching the state of pregnancy, the drug is administered for at least ten weeks. The introduction of "Proginov" in the period of gestation replaces the hormonal function of the ovaries. And only after ten weeks of pregnancy the need for hormonal support completely disappears and the medicine is canceled.
Below we consider the instructions for use for Proginova in infertility.
Use of a medication for infertility during the pregnancy planning phase
The medicine for many women is an excellent alternative to the use of potent hormones. In the presence of IVF, this drug prepares the female body for pregnancy. Unlike many similar drugs, the drug acts quite softly and at the same time sparingly on the female body. It suppresses the work of the ovaries, artificially ensuring the stability of the hormonal background. By stabilizing the amount of estrogen, this medicine also eliminates, among other things, any complications that are triggered by hormonal imbalances. Thanks to this, “Proginova” contributes to:
- Achieving a stable hormonal background, independent of adverse factors in the form of stress, colds and chronic ailments.
- Prevents abortion or miscarriage.
- Improves placental circulation.
- Prevents placental abruption.
This drug is not only a defense against complications, but also guarantees the preservation of pregnancy, and in addition, the viability of the fetus. During pregnancy, the medication is not prescribed. But in practice, pregnancy is often accompanied by this drug. This is necessary against the background of a decrease in estrogen levels and weak labor.
So it is said in the instructions for use to Proginova. Reviews and analogues are presented below.
Analogues of the drug
The known and most commonly used analogues of this medication include funds in the form of Kolpotrofin, Ovestin, Estrokad, Sinestrol, Klimen, Estrovagin, Estrofem, Elvagin, Ethinyl estradiol, and Oestrogel, Folliculin, Dermestril, Klimar, Menorest, Oktodiol, Pausogest and Esterlan.
Reviews
According to the reviews of doctors and patients, it is possible to say that the Proginova medicine is fairly well tolerated and almost does not cause adverse reactions, and in addition, does not affect weight. Negative reviews about this remedy are mainly left by women to whom the drug simply did not fit, as it provoked severely tolerated adverse reactions.
We reviewed the "Proginova" preparation instructions for use and reviews.