In modern pharmacies, you can find quite a lot of drugs that are more or less effective against rhinitis, allergies and asthma. A fairly high interest among the inhabitants is used in the description, the instruction of the drug "Singular", reviews. The average price for this medicine this year is about a thousand rubles per pack. However, some outlets offer medicine for only 800 rubles, while in others the cost is close to one and a half thousand. The difference in price is explained not only by the specifics of the pharmacy, but also by the features of the form of release.
What will help?
Based on the description in the instructions for use of the "Singular", we can conclude that the drug has a positive effect in the following health disorders:
- asthma
- rhinitis caused by allergies.
Bronchial asthma is not only treated with a long course, but can also be prevented by the use of the described medication. As a preventative measure, the use of the “Singular” remedy should be monitored by the attending physician. How can “Singular” be used for children? 4 mg of medicine per day can be eaten by a baby if he is already two years old. In general, this dose is intended for children from 2 to 5 years. And 5 mg per day can already be consumed by children from 6 years and older.
Asthma: how will it help?
If bronchial asthma is diagnosed, already at a dose of 4 mg chewing tablets “Singular” will have the following positive effect on the body:
- will help patients suffering from hypersensitivity to aspirin;
- prevent the development of seizures (regardless of the time of day);
- eliminate aspirin asthma ;
- will prevent the development of asthma amid increased physical activity.
As for rhinitis provoked by an allergic reaction of the body, as follows from the reviews, instructions for use for children “Singular” (in the form of 10 mg chewable tablets) is allowed from the age of 15 and has a pronounced positive effect. The use of the medication facilitates the condition of patients with both seasonal allergies and with the intolerance reaction that does not depend on the time of year. Symptoms are eliminated regardless of the time of day.
What can be replaced?
It should be noted that there are relatively few reviews about the “Singular” tool in the Russian-speaking sector of the Internet. Presumably, this is due to the difference in price (the instructions for use for children "Singular" in general terms are similar to the prescriptions of other chewable tablets) in comparison with analogues. On average, medicines with a similar effect in Russian pharmacies cost about 500 rubles per pack. Most popular items:
- Montelukast
- Montelast
- Singleton
Of course, the instructions for use of the "Singular" and analogues may differ, as well as the main active substance. If you wish, it is categorically not recommended to replace the drug recommended by the doctor with a cheaper one, since cases of individual intolerance are possible, and the patient's condition will only get worse. This is especially true if the medication is selected for the treatment of the child.
However, if there is a desire to save, then you can do without unnecessary risk if you agree on a replacement with your doctor. Reviews about the analogues of "Singular" (instructions for using these funds are usually not more complicated - they either chew tablets or use an inhaler) are generally positive, patients undergoing therapy note the high effectiveness of the drugs.
"Singular": how does it work?
The main active substance that ensures the effectiveness of the described drug is montelukast. This substance belongs to the category of antagonists of leukotriene receptors. On sale, the drug is represented by chewable tablets. Each tablet is coated with an easily digestible coating. The description of the drug "Singular", the full composition and features of use are indicated in the attached instructions.
The tablets are packed in blisters packaged in cardboard boxes. Each box is equipped with a paper liner containing complete information about the medication. Here, without fail, in detail, the description of the "Singular", indications, instructions for use are indicated in detail.
When not recommended?
In some cases, you can use the "Singular" only very carefully, under the supervision of the attending physician, or it is even better to refrain from using the medication, to find a replacement for it. Instructions for use of the 5-, 10-milligram "Singular" for children / adults mentions the following groups of people:
- children under the age of six;
- Persons who do not tolerate the components of the drug;
- pregnant women;
- women during lactation;
- patients with phenylketonuria.
How to use?
So, you already know that all patterns of use are prescribed in the instructions for use of the "Singular". Are you interested in the price of this drug? Many people say that this medicine is effective, but too expensive. The manufacturer indicates that it is better to use the drug in the evening (it has the maximum effect in bronchial asthma). Chew tablets, the moment of use does not depend on the time of eating.
For patients over 15 years of age, the recommended daily dose is 10 mg (taken at a time). It is recommended to use in the evening, before falling asleep. The instructions for use of the "Singular" for children must be studied before purchasing this medicine.
And when will it work?
Instructions for the medical use of the drug "Singular" draws attention to the fact that to achieve a pronounced therapeutic effect, it takes only one day. At the same time, interrupting treatment, barely received the first positive results, is categorically not recommended.
The manufacturer advises to continue treatment in order to achieve maximum control over the situation and prevent the development of asthma attacks. If the disease has passed into an acute form, the use of the medication involves the control of the attending physician and the entire period of exacerbation lasts. This point is indicated in the instructions for use "Singular" for children and adults.
It is allowed to combine the described chewable tablets with GCS in the form of inhalation. The tool does not conflict with bronchodilators, which also allows simultaneous use in therapy.
Pharmacology
When ingested, the active component of the drug “Singular” inhibits CysLT1 receptors. This allows you to affect the mediators that accompany inflammatory processes. An increased activity of the functioning of the bronchi characteristic of asthma is associated with these mediators. Proper use of the drug reduces the amount of secretion generated in the bronchi.
As a result, the swelling of the respiratory tract becomes weaker. In general, this positively affects the condition of the mucosa covering the airways. Proper use of the medication can reduce the frequency and number of seizures. The disease is easier. Try to always carefully read the instructions for use of the "Singular" for children / adults.
On the first day after the active component enters the human body, a bronchodilator effect builds up, which is then maintained for a long time period clearly enough to stabilize the asthmatic. The greatest positive effect is observed if persistent asthma is diagnosed, and bronchodilators do not allow monitoring the patient's condition to a sufficient degree.
Negative effects: what to be prepared for?
According to the instructions for use of the "Singular" for children / adults, you may encounter a number of side effects. Some of them are recorded in a large percentage of cases. Patients complain of:
- cough;
- runny nose;
- headaches;
- nausea
- sore throat;
- abdominal pains;
- an allergy.
Laboratory tests show that liver transaminases are activated.
In some cases, infection of the respiratory system is possible. The upper paths are the first to suffer.
In some patients, bleeding was observed when using the medication. Cases of intolerance are known, explained by the individual characteristics of the body. This can lead to anaphylaxis. With a frequency of less than one case out of ten thousand, practicing treatment with the "Singular" remedy may cause liver damage - eosinophilic infiltration.
Some patients complain of a change in character under the influence of the medication: they become irritable, aggressive. Hostility is possible, sometimes agitation. In some cases, side effects are manifested by tachycardia, the head may hurt, and convulsions rarely occur. Many patients complained that during the treatment period with the use of the "Singular" they constantly want to sleep. Extremely rare, but nevertheless cases of hepatitis were recorded.
Rarely, but aptly: unpleasant side effects
If an allergic reaction develops when using Singular, it is possible not only a relatively safe urticaria, but also an angioedema that creates a danger to the health and life of the patient.
Patients undergoing treatment with this drug are more prone to the appearance of hematomas, erythema. The skin may become rash or itch. In some patients, nose is bleeding, and the pulmonary form of eosinophilia develops. From the gastrointestinal tract, the following side effects may occur:
- upset stool;
- pancreatitis
- dyspeptia;
- nausea, vomiting.
Some patients complain of pain, aching sensations in the muscles, joints, turning into cramps (extremely rare). In young children, therapy is sometimes accompanied by urinary incontinence. At any age, patients treated with the drug "Singular" sometimes complain of fatigue, a general weak state, asthenic syndrome and swelling.
Application features
Based on possible side effects and given the likelihood of their manifestation, "Singular" is considered a drug that is characterized by good tolerance regardless of age. Most of the unpleasant events accompanying the therapy are not serious enough to require a correction of the treatment strategy. The need to cancel the drug "Singular" is rare.
The manufacturer (and, at the same time, doctors) draws attention to the fact that even with the improvement of the patient’s condition, it is very important to continue treatment using the “Singular”, despite tangible progress. The tool is not intended for stopping attacks, its use is not a reason to refuse bronchodilators, since the "Singular" does not replace this group of medicines. The manufacturer also draws attention to the fact that there is no information on the effectiveness of the described drug in acute attacks, therefore, therapy with the use of "Singular" is not recommended for a patient with this diagnosis.
It is important!
Using "Singular", it is forbidden to undergo parallel therapy with aspirin, other drugs of the same group, if an allergic reaction to NSAID drugs has been established. When monitoring the condition of a patient using "Singular", it must be remembered that medical statistics describe cases of treatment accompanied by mental, neurological disorders.
One of the rare diseases found in a small percentage of the population is galactose intolerance due to genetic prerequisites. If an asthma patient suffers from this health disorder, he should not use “Singular” in the form of chewable tablets, since each dose contains lactose in the form of monohydrate in an amount of 10 mg. Similar restrictions apply to asthmatics suffering from lactase deficiency. Serious limitations on the possibility of therapy are imposed by glucose-galactose malabsorption, in which patients also cannot use lactose-containing monohydrate tablets.
Caution is the key to health
If a patient with bronchial asthma has a history of phenylketonuria, the doctor must inform (and the manufacturer indicates this fact in the instructions for use) that one tablet contains aspartame. Its volumes are similar to 0.842 mg of phenylalanine.
Studies of the effects on the human body of the components of the tablets "Singular" have not shown effects on the concentration. It is allowed to control the machine, other moving units during the passage of the therapeutic course.
And if too much?
An overdose of the drug "Singular" can lead to rather unpleasant consequences, therefore it is important to use the tablets correctly, following the recommendations of the manufacturer and your doctor. Research, clinical trials, as well as reviews of patients using the drug contain references to thirst, gag reflex, overexcitation accompanying poisoning of the body. Head, stomach may hurt. Many overdosed individuals complained of a craving for sleep.
There is no specific antidote. In case of body poisoning, symptomatic therapy is necessary.
Combining wisely
"Singular" can be safely used with many medicines designed for patients with asthma, suffering from rhinitis caused by allergies. The tool is combined with both preventive drugs and with drugs used for long-term treatment of these disorders. Compatibility does not depend on the dosage form of the drug "Singular."
If the patient has been treated with corticosteroids in the form of aerosols, the manufacturer recommends switching to the "Singular" smoothly, under the supervision of the attending physician. A sharp change in treatment strategy can provoke negative reactions of the body. Of their own free will, it is not recommended to change one type of medication to another without the recommendation of a doctor and his careful attitude to the situation.
The tool is designed as a base for long-term therapy. Self-medication with its use can lead to unpredictable reactions. In an acute infectious process, the drug can be used in assessing the condition of a patient by a doctor. In such a situation, a combination with other drugs selected by a specialist is usually practiced based on the specifics of the disease.