The tool "Rocefin" describes the instructions as a drug with a bactericidal, antibacterial effect. A medication is available in the form of a powder for the preparation of a solution for injection. The active substance is ceftriaxone.
Injection of drug "Rocefin" instruction allows for intravenous and intramuscular administration.
For patients over twelve years of age, the drug is prescribed one at a time - two grams per day. In severe cases of the disease, as well as in pathologies whose pathogens exhibit moderate sensitivity to the active component, the daily dosage can be increased to four grams.
Newborns (up to two weeks of life) are prescribed twenty to fifty milligrams per kilogram once a day. When calculating the dosage, differences between premature and full-term babies are not made.
Patients from the fifteenth day of life to twelve years of age are prescribed twenty to eighty milligrams per kilogram once a day.
If the child's weight exceeds 50 kg, a dose is prescribed, as for an adult.
Intravenous drip is carried out slowly (especially doses of fifty milligrams per kilogram), not less than half an hour.
The duration of therapy with the drug "Rocefin" recommends that the instructions for use be established taking into account the pathology. After normalizing the level of temperature and eradication (destruction) of the pathogen, it is necessary to continue the administration of the drug for another forty-eight or seventy-two hours.
The medicine "Rocefin" instruction recommends that for bacterial meningitis in young children and infants begin to enter with a dose of one hundred milligrams per kilogram (not more than four grams) once a day. After identifying the pathogen and its sensitivity, the dosage of the drug is adjusted according to the data. The optimal duration of treatment for meningococcal meningitis is four days, for meningitis provoked by Pfeiffer coli (hemophilic coli) - six days caused by pneumococcus - a week.
In Lyme disease, Borreliosis is prescribed at fifty milligrams per kilogram (no more than two grams) per day for children and adults. The duration of therapy is fourteen days.
In case of gonorrhea, the drug "Rocefin" instruction recommends to enter once in a dose of 250 milliliters.
The medicine can be used as a prophylactic in the postoperative period. In accordance with the degree of infectious risk, from 1 to 2 grams is prescribed once for thirty - ninety minutes before the intervention.
For patients with impaired renal activity, dosage adjustment is not necessary if there is no change in liver activity.
In case of severe hepatic and renal failure during treatment, it is necessary to systematically determine the content of the active component of the drug "Rocefin" in the blood and adjust the dosage if necessary.
Despite the ability of the solution to maintain its chemical and physical stability for six hours, it is necessary to administer the drug immediately after preparation.
The color of the ready-to-inject mixture can range from amber to pale yellow. The color of the solution does not affect the tolerance or effectiveness of the drug.
A ready-to-inject mixture should not be added or mixed with other antibiotics due to possible incompatibilities.
About the drug "Rocefin" the reviews of specialists in most cases are positive. Doctors note the high effectiveness of the antibiotic, as well as its good tolerance.
Rocefin powder must be stored at a temperature not exceeding thirty degrees in a dark place. The finished solution for injection is stored at room temperature for no longer than six hours. The shelf life of the drug is three years.