Diabetes patients are becoming more and more every year. This is due to malnutrition and stressful living conditions. Diabetes is an insidious disease that requires constant monitoring and treatment. One of the most popular drugs for controlling this ailment is Gliclazide tablets. Instructions for use should be studied by the patient before starting treatment.
Pharmacological data of the drug
Hypoglycemic agent for oral administration. A product is made as a derivative of the second generation sulfonylurea. Helps in the production of insulin by the cells of the pancreas. Increases the sensitivity of peripheral tissues to insulin. Reduces the time lag between meals and the start of insulin production.
The medication restores the early process of insulin secretion. Glyclazide tablets normalize vascular permeability, reduce blood cholesterol, and prevent thrombosis and atherosclerosis. The active component reduces the perception of blood vessels to adrenaline. If the patient has a history of diabetic nephropathy, then with taking pills, the amount of urine released per day may decrease. This effect on the body has the drug "Gliclazide." Instructions for use are found in each package of tablets. Information must be studied.
Dosage and composition of the tablets "Gliclazide"
When it enters the stomach, the drug is rapidly broken down in its cavity. After 4 hours, 80 mg enters the bloodstream with a single dosage of the drug. Almost 100% combines with blood proteins. It dissolves in the liver and forms metabolites that do not have a hypoglycemic property, but can only affect microcirculation. It is excreted in the urine during the day.
At the beginning of treatment, 80 mg is prescribed once a day. The maximum can be taken 160-220 mg twice a day. Tablets are drunk before meals. Also, the dosage depends on the course of the disease and the degree of damage to the pancreas. You can share the reception. One tablet is taken on an empty stomach, and two hours after a meal, repeat the dosage. How to use the "Glyclazide"? Instructions for use. Price, analogues, the correct dosage - the doctor will tell about all this.
Interaction with other drugs
Glyclazide tablets lose their effect when taken together with certain drugs. These are pyrazolone derivatives, antibacterial sulfonamide drugs, MAO inhibitors, theophylline, caffeine.
With concomitant use with non-selective beta-blockers, the development of hypoglycemia increases, tachycardia and trembling hands, sweating, especially at night, may appear.
When using the medicinal product "Cimetidine" in the plasma, the content of the "Gliclazide" tablets increases. This can lead to severe hypoglycemia. With the simultaneous administration of Glyclazide tablets and Veropomila medication, it is worth controlling the blood sugar level.
Also, along with taking GCS, Glyclazide tablets lower their hypoglycemic properties. Such drugs include diuretics, barbiturates, estrogens, and some anti-TB drugs. Therefore, it is necessary to undergo a full examination of the body before taking the drug "Gliclazide." Instructions for use, price, analogues, possible side effects - all this should be known in advance.
Side effects of the drug
In rare cases, from the gastrointestinal tract, nausea, vomiting, heartburn, diarrhea, pain in the epigastric region can be observed. In blood counts, leukopenia, thrombocytopenia, anemia can occur. After stopping the drug, all these phenomena disappear.
With an overdose, symptoms of hypoglycemia begin. Allergic reactions to drug components may also occur. Be sure to familiarize yourself with the side effects of Glyclazide tablets. Instructions for use contain detailed information.
Indications for taking Glyclazide tablets
The drug is prescribed for diabetes mellitus of the second type of moderate severity, when there is no insulin dependence yet. Also for preventive measures for microcirculation disorders. The medicine is used under the supervision of a physician. First you have to take a blood glucose test. Be sure to follow a diet during treatment, reduce the intake of salt and carbohydrates. Refuse to take flour and sugar.
Overdose of pills
When hypoglycemia develops, the patient should observe bed rest. A 40% glucose solution is administered intravenously. You can give the patient a drink of warm tea with sugar.
After improvement, you need to feed the patient foods rich in carbohydrates. Timely resuscitation measures will help save a person's life.
Must be studied before using the means "Gliclazide" instructions for use. Analogues of the drug have a similar effect.
Contraindications
The drug is not prescribed for renal and liver failure. During pregnancy and lactation, it is not recommended to be treated with Glyclazide tablets. The specialist must assess the possible danger. The drug is taken if the possible benefit to the mother exceeds the harm to the baby.
No agent is prescribed for hypersensitivity to sulfonamides. If an allergic reaction occurs, you should immediately seek medical help.
Analogs of tablets "Glyclazide"
Many drugs have worthy analogues. In most cases, they have identical readings. The substitute for the drug “Gliclazide” are the tablets “Gliclazide mv”, “Diabeton”, “Glidiab”, “Glidiab mv”.
Gliclazide mv
Glyclazide mv tablets have proven themselves well. Instructions for use will tell about contraindications and side effects of this drug. It is used to treat non-insulin-dependent diabetes mellitus with moderate severity. You can not drink this medicine for diabetes of the first type, with pathologies of the liver and kidneys. During pregnancy and lactation, taking the drug is strictly prohibited.
Treatment should be accompanied by sugar control. Among the side effects, nausea, vomiting, diarrhea, and pain in the stomach can be observed. In rare cases, anemia and leukopenia develop. With an allergic reaction to certain tablet substances, a rash may appear. Gliclazide mv has a number of drugs with which there is no compatibility. These are diuretics, barbiturates, estrogens, aminophylline medicines. Certainly, instructions for use should be studied before treatment with Glyclazide MV tablets. The price of the product does not exceed 500 rubles.
Diabeton
Oral hypoglycemic drug. White tablets, slightly convex. On both sides there are designations DIA 60. This suggests that the drug is licensed. This is a great method to counterfeit medicine.
The composition of the drug includes the substance gliclazide. The medicine is prescribed only for adults. You need to drink one tablet once a day. This is best done during breakfast. Depending on the type of diabetes and the general condition, the dosage can be increased to two tablets per day. Glyclazide tablets have the same dosage regimen. Instructions for use describe everything in detail.
When using a high dose of the drug, hypoglycemia may develop. In this condition, it is urgent to seek help from a specialist. It has all the same contraindications and side effects as the "Gliclazide mv" remedy. Instructions for use, price, reviews - all this should be studied before starting treatment.
Reviews on the drug "Gliclazide"
Most often, you can hear positive statements about the pills. Patients note that the drug helps to control blood sugar and contributes to normal health. The only inconvenience is that the medicine should be taken strictly according to the scheme. An overdose can be quite dangerous.