How to use Candiderm cream? Instructions for the use of external funds are presented in the materials of this article. Also, it describes reviews about the mentioned drug, lists its indications and contraindications.
Description, composition and packaging of the medication
In what packaging is Candiderm cream produced? Instructions for use of this tool are enclosed in a cardboard box. It also contains a tube of aluminum with a medicinal substance.
The active components of this medication are clotrimazole, beclomethasone dipropionate and gentamicin sulfate. It also includes auxiliary ingredients in the form of cetomacrogol, sodium dihydrogen phosphate monohydrate, sodium hydrogen phosphate, methyl paraben, benzyl alcohol, propylene glycol, petrolatum, propyl paraben, liquid paraffin and water.
Candiderm ointment has a uniform texture and white color. This drug does not have any characteristic odor.
Pharmacological indicators of local medication
What is Candiderm Cream? Reviews of experts say that it is an antifungal, antimicrobial, anti-allergic and anti-inflammatory drug with a combined composition.
Such an active substance of the drug as beclomethasone has pronounced antipruritic, anti-allergic, anti-exudative and anti-inflammatory properties. Its mechanism of action is based on a decrease in the process of leukocyte accumulation, release of inflammatory mediators and specific lysosomal enzymes, inhibition of the phagocytosis process, as well as an obstacle to the formation of swelling and a decrease in vascular tissue permeability.
An ingredient like gentamicin is an antibiotic. It belongs to the aminoglycoside group, and also has a bactericidal effect. It cannot be said that this component is able to suppress the activity of Klebsiella, Proteus, pseudomonads, enterobacteria, streptococci, Escherichia and staphylococci.
As for a substance such as clotrimazole, it has antifungal properties. Its mechanism of action is based on a decrease in the synthesis of ergosterol, that is, an integral part of fungal cells.
Pharmacokinetics
What kinetic indicators does Candiderm cream have? The instruction for use does not contain any information in this regard. Manufacturers explain this fact by the fact that the ointment in question has a combined composition. This greatly complicates the tracking of its pharmacokinetic characteristics.
Candiderm cream: indications
The drug in question performs well with the following diseases:
- epidermophytosis of the feet ;
- phleboderma;
- dermatoses with a secondary infection;
- allergic dermatosis;
- dermatomycosis (including with lesions of the inguinal region);
- dermatitis after insect bites;
- diffuse form of neurodermatitis;
- eczema
- lichen planus;
- atopic dermatitis;
- anogenital itching.
Contraindications
The external preparation "Candiderm", the analogues of which are listed below, is prohibited for use in the following pathological conditions:
- chicken pox;
- trophic wounds;
- individual hypersensitivity;
- rosacea;
- open wound surfaces;
- post-vaccination reactions on the skin;
- acne vulgaris;
- viral skin lesions;
- tuberculosis of the skin;
- syphilitic reactions on the skin.
Candiderm cream: instructions for use
The drug in question should be applied to the affected areas of the skin twice a day (after waking up and before bedtime). The duration of such therapy depends on the individual tolerance of the patient and the overall effectiveness of the treatment process.
After 4 weeks of active use of the cream, the patient may experience the first undesirable effects.
Do you use Candiderm ointment in pediatric practice? Reviews of doctors report that the age limit for the use of this tool is a life period of up to 16 years.
If necessary, then by decision of the attending physician, this medication can be prescribed for children aged 7-16 years.
Side effects
What side effects does the Candiderm medication (cream) cause? The instruction states that prolonged therapy with this agent can lead to systemic reactions such as inhibition of the adrenal cortex.
With proper use of the drug, negative effects are extremely rare, and are also mild and temporary.
So, against the background of the use of “Candiderm”, the following allergic responses may occur in patients:
- striae, contact dermatitis, maceration, urticaria;
- dry skin, swelling, peeling, hyperemia;
- telangiectasia, furunculosis, hypertrichosis, pyoderma;
- burning sensation, perioral dermatitis, hypopigmentation, folliculitis;
- steroid acne, rashes, atrophic changes in the skin.
Drug overdose
When applying a large amount of cream on large areas of the skin, the patient may experience the following symptoms of an overdose:
- weight gain;
- hypokalemia;
- increase in blood pressure;
- glucosuria;
- manifestations of hypercorticism.
With such deviations, the patient is corrected for electrolyte balance, as well as carry out syndromic therapy.
Special recommendations
It is forbidden to use the ointment "Candiderm" in ophthalmic practice. Also, this drug can not be applied to the skin located around the eyes.
Occlusive dressings significantly increase the effectiveness of the drug.
When using this medication with dressings, the transdermal absorption of its active elements (in particular beclomethasone and gentamicin) may increase. This can cause negative systemic reactions.
When observing fungal and bacterial resistance, the drug is canceled.
In the treatment with aminoglycosides, the development of cross-resistance is characteristic.
In pediatric practice, the ointment "Candiderm" is used only according to indications and under medical supervision.
Applying a medication and applying dressings to large areas of the skin can lead to suppression of the pituitary-hypothalamic-adrenal system.
Analogues of the drug and its cost
What can replace Candiderm cream? Analogues of this tool are sold in all pharmacies and dispensed without a medical prescription. The most popular substitutes for the mentioned medication are the following: "Belogent", "Betagenot", "Betaderm".
How much does Candiderm ointment cost? The price of this local remedy is quite high (according to most patients). You can get one tube of antifungal drug for 450-470 rubles.
Reviews about the drug
Doctors give the Candiderm cream unique antifungal, antipruritic and anti-inflammatory properties. They leave only positive reviews about this drug. According to them, the medication in question is fairly well tolerated by patients and can achieve the desired result in a short time.
As for patients, they also talk about the high effectiveness of this medicine. After several applications of the cream, the symptoms of most skin diseases are significantly reduced.