Analogs, reviews and instructions for use of "Betagistin" prove that the drug is safe enough to receive and shows a good result. But it is not recommended for certain categories of patients. About this - below.
special instructions
During the period of treatment with a pharmaceutical agent, it is necessary to carefully monitor the condition of patients with a gastric and duodenal ulcer in the anamnesis, and also follow the instructions of Betagistin.
The use of the drug in special periods:
- Pregnancy. There is no information regarding the use of Betagistin in pregnant women. The results of animal studies are insufficient to assess the effects on pregnancy, embryo / fetus formation, childbirth and postnatal development. A possible threat to humans is unknown. Betagistin should not be used during pregnancy, with the exception of an undeniable need.
- The period of breastfeeding. It is unknown whether Betagistin passes into human breast milk. The benefits of using a pharmaceutical for mom should be weighed against the benefits of breastfeeding and the potential risk to children.
- Children. Due to the lack of information regarding safety and effectiveness, this drug is not recommended for children.
- The ability to influence the reaction rate when driving vehicles or working with other devices.
"Betagistin" is presented to cure Meniere's syndrome, characterized by a triad of the main signs: dizziness, hearing loss, tinnitus, as well as for the symptomatic treatment of vestibular dizziness. Both conditions can adversely affect the ability to drive a car and work with other mechanisms.
The use of "Betahistine"
Consume inward. Take regardless of food intake. The recommended starting portion is 24–48 mg of betahistine dihydrochloride. The daily dose is equally distributed in 2-3 doses. The dose is selected personally depending on the effect. A decrease in the severity of symptoms of the disease in some cases can be traced only after a couple of weeks of cure. Suitable results are achieved by taking the substance for some months.
The instruction "Betahistine 24" indicates the following application:
- 8 mg: one or two capsules (in the morning, at lunch, and in the evening).
- 16 mg: in a half-whole capsule (in the morning, at lunch and in the evening).
- 24 mg: on the capsule (in the morning and in the evening).
Elderly patients. Although at this time the results of medical studies in this group of patients are limited, the wide experience of using Betagistin in the post-registration period makes it possible to assume that dose adjustments for this population are not required.
Patients with renal or liver failure. In this group of patients, specialized medical trials were not conducted, but in accordance with the experience of the post-registration use of Betagistin, a dose adjustment is not necessary.
Wertrand
An agonist of the H1-histamine receptors of the vessels of the inner ear and an antagonist of the H3-histamine receptors of the vestibular nuclei of the central nervous system. It does not have a great effect on H2-histamine receptors, which makes hemodynamics better in the vascular strip of the inner ear due to the calming effect on the precapillary sphincters of the cochlea and labyrinth. Reduces manifestations of Meniere's syndrome and vertigo.
Method of use and dosage:
When eating. The amount of substance is:
- 8 mg: one to two capsules three times a day.
- 16 mg: in a half-whole capsule three times a day.
- 24 mg: capsule twice daily.
The optimal daily serving is 48 mg.
The amount of the drug and the duration of therapy must be selected personally in connection with the patient's response to treatment. Improvement, as a rule, is noticed already at the beginning of therapy, but it can be gradual and manifest even after a couple of weeks. A stable result in some cases is achieved after a few months. Dose adjustment in elderly patients, as well as in patients with renal and / or liver failure, is not required.
"Vestibo"
"Vestibo" is an artificial likeness of histamine. It is considered a weak histamine H1 receptor agonist and a fairly strong histamine H3 receptor antagonist. It exhibits a histamine-like and vasodilating effect. Affects cochlear blood flow and the main vestibular apparatus. It has a central result, being an antagonist of histamine H3 receptors.
Helps to cure the following pathologies:
- reduces the frequency and intensity of severe dizziness;
- reduces tinnitus;
- significantly contributes to the improvement of hearing in cases of its decrease.
Instructions for use of the Betagistin analogue - Vestibo tablets: must be taken with food without chewing, with a small amount of water.
- 8 mg: one tablet two to four times a day.
- 16 mg: one tablet two to four times a day.
- 24 mg: a half-whole tablet twice a day.
The maximum daily serving is 48 mg.
Cinnarizine
Cinnarizine is a more affordable and practical analogue of Betagistin. It varies in composition, but also belongs to the group of substances intended to eliminate dizziness. Sold in packs of 50 tablets, for this reason it is even cheaper than the “original”, which has a total of 30 tablets per pack.
- In chronic cerebrovascular insufficiency - 25 mg three times a day, in drops - 8 drops three times a day or in a capsule (75 mg) once a day.
- In the pathology of peripheral circulation - 50-75 mg three times a day.
- For the prevention of seasickness and airborne disease - 25 mg 30 minutes before a future trip, if necessary, repeat the dose after 6 hours.
- For a child from 5 years - 1/2 dose for seniors.
The maximum daily dose is not required to be higher than 225 mg.
With a significant susceptibility to the product, therapy begins with 1/2 dose, increasing it over time. To achieve a rational therapeutic result, a medication must be taken continuously, for a long time - from a couple of weeks and up to several months.
Tagista
"Tagista" - a special medication that improves the microcirculation of the labyrinth, used for problems with the vestibular apparatus. The drug affects mainly histamine H1 and H3 receptors. By the method of direct agonistic effect on histamine H1 receptors, as well as indirectly through influence on histamine H3 receptors, it normalizes microcirculation and capillary transmittance, restores endolymphatic pressure in the labyrinth and cochlea.
Together with this, "Betagistin" increases arterial blood flow, namely in the basilar artery. It has a fairly clear central effect, representing an inhibitor of histamine H3 receptors of the nuclei of the vestibular nerve. Restores the conductivity in the neurons of the vestibular nuclei at the level of the brain stem. A manifestation of the noted qualities is considered to be a reduction in the frequency and intensity of dizziness, a decrease in the buzz in the ears, and improvement in hearing if it decreases.
It is applied inside with food.
- 8 mg: one to two tablets three times a day.
- 16 mg: a half-whole tablet three times a day.
- 24 mg: a tablet twice a day.
Improvement, as a rule, is recorded already at the beginning of therapy, a stable therapeutic result occurs immediately after two weeks of cure and can increase within a few months after complete cure. Therapy is quite long. The duration of the course is only personal.
Westicap
The artificial semblance of histamine exhibits a histamine-like and vasodilating effect. It is considered a weak agonist of H1-histamine receptors and a fairly strong blocker of H3-histamine receptors.
Affects the following devices:
- vestibular;
- central;
- cochlear blood flow.
The instruction "Betahistine" (analogue) indicates that:
- Vasodilation in the inner ear occurs through H3 and H1 histamine receptors.
- Inhibitory results with respect to the vestibular nuclei are realized directly through H3-histamine receptors.
- Inhibitory effects are observed with the pulsating activity of the ampullar receptors.
Dosage: when eating, 8-16 mg three times a day. Either by capsule (24 mg) twice a day. The dose and duration of taking "Vestikapa" are selected for each patient only personally.
Reviews
The instruction to "Betagistin" does not give reviews, but there are recommendations for admission from patients:
- reduce the dose in case of serious complications with the gastrointestinal tract;
- if there is no effect for some weeks, it is necessary to cancel the medication.
Advantages and disadvantages
Pros:
- nice, affordable cost;
- a small number of likely side effects;
- the variety of the proposed concentration of the active element (release forms); well eliminate dizziness and coordination pathology;
- in general, a rather favorable experience of practical use.
Minuses:
- in some cases, burning sensation, headaches;
- not on all patients the product shows an appropriate result;
- probable remission of dizziness;
- low bioavailability, in comparison with analogues.