For diseases of the central nervous system, doctors often prescribe the nootropic drug "Gliatilin". Reviews of the drug indicate that it effectively helps with cerebrovascular disorders, memory impairment and cognitive functions, as well as with concussion. The medicine has few contraindications and side effects. This safe drug stimulates the brain and helps restore functions lost after an injury or stroke.
Composition and effect of the drug
The active component of the drug is choline alfoscerate. The drug belongs to the group of central cholinomimetics. The drug substance enters the brain and breaks down into choline and glycerophosphate. These compounds have a therapeutic effect on the central nervous system.
Choline stimulates the synthesis of acetylcholine - a substance that is a conductor of nerve impulses. As a result, the transmission speed of signals from one neuron to another increases.
In addition, the drug is a neuroprotector. Glycerophosphate is involved in the production of phospholipids. These substances strengthen the membranes of nerve cells. Adequate production of phospholipids protects neurons from the harmful effects.
The medicine also improves cerebral circulation and metabolic processes in the central nervous system. This helps to restore the brain after serious injuries and strokes.
The drug improves memory and cognitive functions (thinking, attention). This helps rehabilitate patients with senile dementia, Alzheimer's disease and other forms of dementia.
The medicine has a calming effect on the nervous system. After taking the drug, the patient improves mood, irritability and anxiety disappear. In this case, there is no sedation and drowsiness.
There are two forms of drug release:
- Capsules "Gliatilina". Each of them contains 400 mg of the active ingredient. Capsules are gelatin coated. The composition of "Gliatilin" also includes auxiliary ingredients: titanium dioxide, sorbitol, glycerin, food additives. These substances are necessary for better absorption of the active component.
- "Gliatilin" in ampoules. This is a clear solution for injection containing 1000 mg of the active ingredient in 4 ml of distilled water. It is intended for intramuscular or intravenous drip.
Indications
The following indications for the use of "Gliatilin" :
- Traumatic brain injuries. The drug is used in the acute period of the pathology. This medicine is especially effective for damage to brain stem structures, accompanied by loss of consciousness and coma.
- The recovery period after strokes of various etiologies. With an ischemic form of pathology, the drug can be prescribed in the acute period.
- Psycho-organic syndromes occurring with confusion, impaired memory, apathy and impaired concentration.
- All types of senile dementia, including Alzheimer's disease.
- Emotional distress. The drug is effective for neurotic disorders, accompanied by irritability, loss of interest in life and anxiety.
- Depressive conditions in dementia in the elderly (senile pseudomelancholy).
- Delayed psychomotor development in children.
Contraindications
This drug has very few contraindications. The instruction to "Gliatilin" prohibits the use of the drug in the presence of allergies to its active ingredient and additional ingredients. And also this remedy should not be taken during pregnancy and breastfeeding.
Side effects
In most cases, this medicine is well tolerated. However, due to its cholinomimetic effect, nausea may occur in some patients. This is not a reason to stop taking the drug, but requires a dosage reduction.
In patients with hypersensitivity to the components of the drug, allergic reactions can occur. In such cases, the drug should be discontinued and consult a doctor immediately.
If the recommended amount of the drug is exceeded, an overdose develops. This condition is expressed in increased nausea and dyspeptic symptoms. Typically, these symptoms disappear on their own after a dose reduction. It is not necessary to interrupt the course of treatment after an overdose.
How to take the drug
"Gliatilin" in capsules is best taken before meals. The required dosage of the drug is determined by the doctor. Adult patients are prescribed an average of 2-3 capsules per day (for 2-3 doses). The course of treatment lasts from 3 to 6 months.
"Gliatilin" in ampoules is administered intramuscularly or intravenously as part of droppers. If the drug is used for infusion, then 1 ampoule (4 ml) is dissolved in 50 g of sodium chloride (saline). During the day, no more than 3 g of choline alfoscerate can be administered dropwise. With intramuscular administration, 1 ampoule of the drug per day is prescribed. After improving their well-being, patients are transferred to the encapsulated form of the drug.
In the treatment of children, it is preferable to use an injectable form of the drug. This is because the capsule is difficult to swallow for a small child. At the age of 3 years, 1-3 ml of the solution is administered per day. Older children are prescribed an adult dosage of 4 ml (1 ampoule) daily. The course of therapy lasts from 10 to 12 days.
In capsule form, children from 1 year are prescribed 400 mg of the drug twice a day. For the convenience of taking the medicine, you can pierce the capsule with a syringe and stretch its contents. Then you need to remove the needle, pour the medicine into the baby’s mouth and let it be washed down with water.
special instructions
Instructions for "Gliatilin" reports that the drug does not affect concentration. Therefore, during the course of treatment, you can drive a car and perform complex types of work.
The medicine does not interact with other medicines. Therefore, "Gliatilin" can be used as part of complex therapy of diseases of the nervous system.
Storage, price and analogues
The drug is recommended to be stored at a temperature of no more than +25 degrees. Capsules remain valid for 3 years, and the solution for 5 years.
The medicine is dispensed from prescription pharmacies. Despite the relative safety of the drug, it cannot be taken on its own. The price of capsules is from 720 to 820 rubles, and the solution - from 550 to 670 rubles.
Often patients are interested in the structural analogues of Gliatilin. You can choose nootropic drugs that also contain choline alfoscerate. These include:
These drugs are available in capsules and ampoules. The cost of such drugs is from 350 to 1100 rubles.
There are structural analogues of Gliatilin, which are produced only in the form of an injection solution. These include:
- "Noocholin Rompharm."
- Gleazer.
The cost of these drugs is from 210 to 330 rubles.
Patient Reviews
Patients leave a lot of positive reviews about Gliatilin. This drug helped many patients recover from severe head injuries or a stroke. Patients showed improved movement after paralysis, headaches and dizziness disappeared, and memory increased. People note that the maximum therapeutic effect occurred after the use of injections, and the capsules acted much weaker. This suggests that in severe cases it is preferable to use an injectable form of the drug.
Some people took this drug while doing heavy mental work. This helped them overcome fatigue. Their performance and vigor increased, memory and concentration of attention improved.
Positive feedback about Gliatilin is left by the parents of young patients. People report that children with developmental delays after a course of treatment have become better at talking, they have increased vocabulary and memory. Kids quickly learned to sit down, stand on their legs and walk. It can be concluded that this drug stimulates the development of the child.
Negative reviews of "Gliatilin" regarding the use for children are associated with the lack of effect of therapy. Usually in such cases, the drug was used in the form of capsules. Parents note that the use of an injectable form of the drug is more effective. The effect of treatment with capsules sometimes has to wait a very long time.