What is the medicine "Sulgin"? What helps, how to take this remedy? You will find answers to all the questions in this article.
Form, composition
Before telling you what “Sulgin” helps from, you should tell in what form this medicine goes on sale. This medication can be purchased in the form of tablets, the active ingredient of which is sulfaguanidine, and additional substances - primogel, calcium stearate and starch.
Drug features
The drug "Sulgin" from what helps? According to the attached instructions, this tool has antidiarrheal and antibacterial effects. It is highly active against gram-negative and gram-positive bacteria, including pathogens of intestinal infections.
The medication in question is rather poorly absorbed by oral administration. It acts mainly in the intestinal lumen.
The active substance of this drug - sulfaguanidine - inhibits dihydroteroate synthetase and competes for receptors with para-aminobenzoic acid. Such an effect of this component slows down the biological synthesis of tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidines in the cells of the pathogen.
What helps "Sulgin"
Experts indicate the following indications of the drug in question:
- bacterial dysentery;
- colitis or enterocolitis with signs of diarrhea;
- preoperative preparation for intestinal surgery.
Medication "Sulgin" what helps? Tablets for oral administration are often used in cases of suspected carriage of typhoid fever or dysentery pathogens.
Mode of application
Now you know what Sulgin helps from. How should this drug be used correctly? In acute intestinal infections, this drug must be taken orally. On the first day of therapy, 1-2 g is prescribed up to 6 times a day. As for the second and third days, the indicated dosage is maintained, however, the frequency of administration is reduced to 5 times a day. On the fourth and fifth day, the frequency of use of this medicine in a dose of 1-2 g is up to 4 and up to 3 times a day, respectively.
The duration of treatment with this medication should not exceed more than two weeks. Children under 3 years old are recommended to take 200 mg of the drug per 1 kg of weight per day (divided by three times) for one week.
Babies from 3 years old are given 400-750 mg of the drug up to 4 times a day.
In the process of carrying out preventive measures for postoperative complications, patients are recommended to take 50 mg of the drug per 1 kg of weight three times a day for 5 days before the intervention, and then for another week after the operation.
Side effects
Having found out what “Sulgin” helps from, you should definitely familiarize yourself with its side effects. According to the instructions, after using this tool in patients, the following negative effects often occur:
- depression, myalgia, headache, necrolysis, apathy, photosensitivity, tremor;
- rash, dizziness, itching, neutropenia, nausea, thrombocytopenia, gastritis, agranulocytosis, cholestasis, anemia;
- fever, bronchospasm, vomiting, arthralgia, diarrhea, crystalluria, anorexia, polyuria;
- glossitis, increased urea concentration, stomatitis, toxic nephropathy, erythema polymorphic-bullous;
- increased concentration of transaminases, kidney damage, hepatitis, hematuria, interstitial nephritis, toxic allergic myocarditis;
- oliguria, hypercreatininemia, epidermal angioedema, anuria.
Overdose cases
When taking high doses of the drug “Sulgin”, symptoms may occur that are characteristic of all sulfa drugs (for example, vomiting, fainting, nausea, dizziness, intestinal colic, fever, headache, depression, hematuria, crystalluria).
The treatment of such conditions is carried out by canceling the medicine, as well as washing the stomach, drinking plenty of water and forced diuresis.
Recommendations
In acute need, the medication in question can be used in conjunction with other antibacterial agents and sulfonamides, which are well absorbed from the intestine.
During treatment with Sulgin, it is recommended to strengthen diuresis, as well as take B vitamins in parallel.
Consumer reviews
Most patients taking the drug "Sulgin" are satisfied with its therapeutic effect. They argue that this tool is good and quickly enough eliminates all the symptoms of intestinal poisoning, including diarrhea.
Despite all the positive reviews, it should be noted that sulfaguanidine, as well as medicines based on it, have long been banned in developed countries due to their extreme nephrotoxicity.