"Chlorprotixen": instructions for use, analogues, composition and reviews

In the article, we consider the instructions for use and reviews for the Chlorprotixen medication.

The drug is a pharmacological group of drugs with antipsychotic therapeutic efficacy. It is used to treat a variety of pathological psychotic conditions.

Composition, dosage form

As indicated by the instructions for use, "Chlorprotixen" is produced in tablet dosage form.

The pills are coated with a special enteric film coating. They are intended for oral administration (inside). The tablets have a light yellow color, a biconvex surface and a rounded shape. The main active element of the drug is chlorprotixen hydrochloride, the content of which in one tablet is 50 and 15 mg.

In addition, it includes the following additional components:

• macrogol 6000 and 300;
• lactose monohydrate;
• talc;
• corn starch;
• aluminum varnish based on the yellow dye "Sunny Sunset".
• sucrose;
• hypromellose;
• talc;
• calcium stearate.

According to the instructions for use, Chlorprotixen tablets are packaged in contour cells of 10 pieces per pack. A cardboard box may contain 5 and 3 contour cell packs (each containing 50 and 30 tablets, respectively), as well as an annotation to the medical device with a detailed description.

Therapeutic properties of the drug, pharmacokinetics

What else can you learn from the instructions for use? "Chlorprotixen" has an antipsychotic effect, which is carried out by suppressing the functionality of dopamine receptors in the structures of the central nervous system.

Due to this, the drug reduces the severity of psychotic reactions. Mainly such as motor and speech arousal, the occurrence of auditory and visual hallucinations. In addition, the drug has a mild sedative (sedative) and analgesic therapeutic effects.

After administration, a personally acting element is rapidly and almost completely absorbed into the general bloodstream. After that, it is evenly distributed in the tissues, penetrating the blood-brain barrier.

Subsequently, the active substance is metabolized in the liver with the formation of inactive decay products, which are excreted through the kidneys with urine.

Indications for the appointment of a medication

In accordance with the instructions for use, Chlorprotixen is used to treat a variety of psychotic conditions. Their list includes:

• Psychosis. Severe mental disorder, which can manifest itself as schizophrenia and manic states, occurring with a significant increase in speech and motor activity, as well as specific symptoms in the form of auditory and visual hallucinations.
• Mental pathologies in the elderly. They are manifested by irritability, confusion, as well as hyperactivity.
• Depression. A pronounced and prolonged decrease in mood, which is associated with insufficient production of the neurotransmitter serotonin in the structures of the brain.
• Behavioral disorders in children. Including syndrome of changes in concentration.
• Severe sleep disturbance. It is characterized by problems in falling asleep and early awakening.
• Neurosis or psychosomatic disorder, in which pain occurs of different localization in the patient’s body, not associated with the formation of somatic pathologies. Similar neurotic pains are most often localized in the region of the heart.
• Withdrawal syndrome with advanced stages of alcoholism.

In addition, this medication can be used in combination with analgesics (painkillers) to reduce the severity of severe pain syndromes.

Instructions for use with Chlorprotixen are very detailed.

Contraindications to the use of this medication

It is necessary to highlight some physiological and pathological conditions of the body, in which the use of the drug "Chlorprotixen Zentiva" is contraindicated. These include:

• inhibition of the functionality of the central nervous system of various origins (intoxication, severe infectious pathologies, poisoning with barbiturates, intoxication with alcoholic beverages, etc.);
• coma of various nature of occurrence, which are characterized by the general severe condition of the patient, lack of consciousness, decreased reflex activity;
• pheochromocytoma is a benign hormonal tumor in the adrenal medulla. With it, adrenaline production increases, and systemic blood pressure also rises;
• pathologies of the red bone marrow, in which the picture of peripheral blood changes, and also a violation of the normal ratio of its various elements occurs;
• vascular collapse - a critical decrease in blood pressure levels with the occurrence of multiple organ failure;
• intolerance to any of the substances of this medication.

All this is said in the instructions for use.

Price, reviews and analogues of Chlorprotixen will be presented below. Before prescribing the medicine, the specialist must make sure that the patient does not have contraindications.

Dosage and Administration

The tablets must be taken orally. And do not chew, but drink plenty of water. The dosage and dosage regimen depend on the clinical indications:

1. Psychoses of various etiologies, including schizophrenia and some manic states - the recommended initial therapeutic dose is 100-200 mg. After that, it is gradually increased until the desired effect is achieved, usually up to 300 mg per day. If necessary, the dosage can reach up to 1200 mg. After achieving a therapeutic result, patients are transferred to a maintenance dose. It is 200 mg per day. The daily dosage is recommended to be divided into 2-3 doses. This medication has a slight sedative effect, so that the bulk of the daily dose is taken in the evening before bedtime. This is confirmed by the instructions for use with Chlorprotixen.
2. With withdrawal symptoms, which develops as a result of drug addiction or chronic alcoholism, the recommended therapeutic daily dosage is usually 500 mg in 2-3 doses. The duration of the course of such therapy in most cases is 7 days. As the severity of the manifestations of this pathological condition of the patient decreases, they are transferred to maintenance dosages, which vary from 15 to 45 mg. The use of the drug in such doses significantly reduces the risk of re-binge.
   
3. With mental disorders in elderly patients, which include confusion, excessive motor activity, increased irritability, the recommended drug dosage is 20-90 mg per day. It must be divided into 3 doses during the day. So it is indicated in the instructions for use to "Chlorprotixen zentiva." Reviews assure - the use of the drug according to this principle is convenient and effective.
4. Behavioral disorders in childhood - the medicine is used at the rate of 0.5-2 mg per kilogram of body weight of the child.
5. In case of neurosis, psychosomatic disorders, depressive states of various etiologies, tablets are used as monotherapy, or in combination with sedative medications and antidepressants. Therapeutic daily dose can reach 90 mg, for 2-3 doses. Given that this medication is not addictive, it can be prescribed for a very long time period.
6. With severe insomnia, the therapeutic dosage of the drug is 15-50 mg. Take 2 hours before bedtime.
7. With severe pain, the drug is prescribed in combination with analgesics. The dosage of the drug in this case can range from 15 to 300 mg per day, which depends on the therapeutic effect.

Most often, the duration of treatment with tablets is determined by the attending physician individually.

In the instructions for use with Chlorprotixen, the price and analogues are not indicated.

Side symptoms

Against the background of the use of such a drug, the occurrence of negative reactions from some systems and organs is possible:

1. Digestive system - cholestatic jaundice, which is caused by a violation of the outflow of bile in the structures of the hepatobiliary canal, dry mouth.
2. Nervous system - mild extrapyramidal syndrome, a paradoxical increase in anxiety (especially in the initial stages of therapy in patients with manic disorders and schizophrenia), excessive fatigue, dizziness.
3. Cardiovascular system - tachycardia, changes in the electrocardiogram, lowering blood pressure when changing position from horizontal to vertical. Such information is contained in the instructions for use. The price of Chlorprotixen Zentiva is acceptable.
4. The endocrine system is an increase in the size of the mammary glands in men (gynecomastia) and galactorrhea (the formation of breast milk, which is not associated with the lactation period) that occurs due to a change in the level of prolactin in the blood, a change in libido (attraction to persons of the opposite sex, lack of sexual desire).
5. Sensory organs - clouding of the surface of the cornea and lens of the eyes, which often leads to a decrease in visual acuity and impaired accommodation.
6. Metabolism - excessive sweating (hyperhidrosis), increased appetite with increased body weight.
7. Red bone marrow and blood - leukocytosis or leukopenia, a marked decrease in the number of granulocytes, anemia, which are associated with the destruction of red blood cells.
8. The skin is an increase in the sensitivity of the skin to light, which is often accompanied by an inflammatory reaction (photodermatitis). It also describes the instructions for use with Chlorprotixen. Price varies by region.
   

If pathological reactions occur during the use of the medication, the possibility of subsequent administration is determined by the attending specialist.

special instructions

Before prescribing such a pharmacological drug, the doctor carefully reads the instructions, and also draws the patient's attention to some features of its proper use, which include:

1. Against the background of treatment with this medicine, false-positive results of laboratory tests for pregnancy and bilirubin in the blood are possible.
2. In chronic alcoholism, Raynaud's syndrome and cardiovascular pathologies, the ratio of benefit and risk from the use of the drug is taken into account.
3. Alcohol consumption is excluded during the treatment with “Chlorprotixen Zentiva”. Instructions for use must be strictly observed.
4. The appointment of this medication is not recommended for patients with epilepsy, heart disease, atherosclerosis, and a decrease in the functionality of the kidneys and liver.
5. The use of this drug during pregnancy and lactation is excluded.
6. The active element of the drug can interact with a large number of medicines of other pharmacological groups, therefore, a doctor should be warned about their use.
7. Against the background of therapy, it is forbidden to perform hazardous work associated with increased concentration of attention.

This is stated in the instructions for use with Chlorprotixen. Reviews and analogues will be considered further.

Similar drugs

There are many medicines with the same active substance. The list of analogues of this tool includes:

• "Haloperidol";
• "Invega";
• "Etaprazil";
• “Resolpt”;
• Kvetipin;
• Azaleptin;
• Neurispin;
• Azalepton
• "Abilifay";
• Egonil;
• "Sulpiride";
• "Rileptide";
• Azapin;
• Olanzapine

We will not consider in detail instructions for use with analogues of Chlorprotixen.

Cost

Since we are talking about instructions for use with Chlorprotixen and reviews, the price of the drug should also be given a little attention.

It has already been said that it is acceptable. The cost of the medicine depends on the number of pills in a pack and the dosages:

• 30 tablets of 15 mg - 215 - 240 rubles;
• 50 tablets of 15 mg - 305 - 338 rubles;
• 30 tablets of 50 mg - 309 - 348 rubles;
• 50 tablets of 50 mg - 434 - 489 rubles.

Patient Comments

There are a lot of reviews about this medication, but among them there are both positive and negative.

Patients on the background of taking this drug noted its effectiveness. But numerous adverse reactions are present.

They had severe headaches, in which they had to take analgesics, as well as reactions from the digestive organs. For example, nausea, stomach pain, upset stool.

However, patients say this drug is very effective. It quickly helps with a variety of mental disorders. This applies to all kinds of depressive disorders, neurosis, etc.

Reviews of specialists about this medication in most cases are positive.

However, doctors indicate that Chlorprotixen Zentiva is a serious medication that should in no case be used uncontrollably.

Be sure to get a medical consultation before an appointment, undergo an examination, and then get an appointment from a doctor. Only in this case, the drug will help get rid of the above problems, and its use will be advisable. Otherwise, this medicine can cause serious harm to health.

We examined the Chlorprotixen medication for instructions for use and reviews.