Laboratory Bouchara-Recordati (France) for many years produces vaginal tablets (suppositories) "Terzhinan." They have successfully established themselves in clinical practice. The composition of the candles "Terzhinan" allows you to effectively treat various infectious and inflammatory diseases of the female genital area.
The composition of the funds
"Terzhinan" is a combination drug designed for topical use in the field of gynecology. The composition of the drug has several components:
- Ternidazole Negatively affects anaerobic bacteria, Trichomonas.
- Neomycin sulfate. It is a broad-spectrum antibiotic. Gram-positive and gram-negative bacteria are sensitive to it .
- Nystatin. Antifungal antibiotic of the polyene group. Effective against fungi of the genus Candida.
- Prednisone. It is a corticosteroid. It has a desensitizing and anti-inflammatory effect.
The composition of the drug is very well thought out. In candles "Terzhinan" ternidazole and nystatin, for example, are combined for a reason. In 60% of cases, against the background of the use of nitroimidazoles (and ternidazole just refers to them), candidiasis infection occurs in women. Nystatin, on the other hand, fights fungi of the genus Candida.
Another rational combination is neomycin and nystatin. These components have different mechanisms of action on microorganisms. Because of this, neomycin and nystatin to some extent potentiate the effects of each other. This, in turn, allows the manufacturer to make the drug safer by reducing the number of active components.
Features of the dosage form
The rational composition of the candles "Terzhinan" is not the only advantage of the drug. The medication has a convenient and effective dosage form:
- The vaginal tablet has a smooth glossy surface, rounded edges. Such features of the drug make it easy to enter without irritating the mucous membrane.
- The candle has a compact elongated flat shape. The medicine is in contact with a significant area of the mucous membrane. When the pill is in the vagina, the sensations of the presence of a foreign body inside are minimal.
- The medicine has a special layered structure. The manufacturer creates such tablets that do not disintegrate in the vagina, but gradually dissolve. Each layer of the candle is in contact with the mucous membrane and has the desired effect.
The medicine is sold in pharmacies in small cardboard boxes. Each of them contains a package of tablets. In one package can be 6 or 10 vaginal suppositories.
Indications for use
The composition of candles "Terzhinan" allows you to use them in the treatment of a wide range of diseases. The medicine is prescribed by doctors:
- with fungal vaginitis provoked by a pathogen such as Candida albicans;
- with bacterial vaginitis, arising from the banal pyogenic microflora;
- with trichomonas vaginitis;
- with vaginitis due to a mixed infection.
In various diseases, the drug shows different efficiencies. It helps very well with bacterial vaginosis. With this diagnosis, the effectiveness of the drug is 94%. Studies have shown that at the level of 93% is the effectiveness of candles "Terzhinan" with bacterial vaginitis, genital trichomoniasis. The same indicator for genital candidiasis is 86%.
There is another indication for candles "Terzhinan", not related to the need for drug treatment of any disease, is the prevention of infection. Usually, a medicine is prescribed before the surgical treatment of gynecological pathologies, before and after the installation of the contraceptive spiral, before abortion, childbirth, etc.
How is the tool used and what effect does it have
Vaginal tablets are very easy to use. Their treatment is recommended in the evening before bedtime. Apply candles as follows:
- in the evening take 1 tablet and lower it into water for 20-30 sec .;
- the prepared candle is inserted deep into the vagina;
- after the introduction of the drug, they lie on the bed for about 15 minutes.
The average course of treatment is 10 days. If mycosis is confirmed, the duration of treatment is increased to 20 days. Vaginal tablets must be used daily. Candles "Terzhinan" during menstruation also need to be used, because only through continuous treatment can achieve a positive result.
During treatment, the main symptoms of the inflammatory process (pain, itching, burning, hyperemia) quickly enough stop. This is due to prednisone. This component of the drug normalizes microcirculation in the mucous membrane lining the vagina. Due to this, the influx of medicinal components to the site of inflammation improves, and exudation phenomena decrease.
Side effects
Some women experience side effects during the use of the drug. In very rare cases, patients at the very beginning of treatment complain of local irritation, a burning sensation in the vagina. Skin allergic reactions are sometimes observed.
Cases with the appearance of side effects from the use of candles "Terzhinan" are not too frequent. This allows us to conclude: vaginal tablets in most cases are well tolerated. The drug can even be used during pregnancy as prescribed by the doctor. The medicine does not provoke the occurrence of any unpleasant consequences. On the contrary, it has a positive effect. In pregnant women with vaginosis-vaginitis and the threat of termination of pregnancy, prednisone normalizes estrogen metabolism, reduces the immune conflict between the fetus and mother.
Special instructions and contraindications
In relation to the indications for the use of candles "Terzhinan" established one special indication. Without any concerns, the medicine can be used from the second trimester of pregnancy. In the first trimester, as well as during lactation, vaginal tablets are used with extreme caution. The doctor may prescribe the drug only if the expected benefit of the therapy for the mother outweighs the potential risk to the fetus or newborn.
There is another recommendation from experts. If vaginitis, trichomoniasis is detected, a woman should inform her sexual partner about this. He must be examined. If any problem is identified, treatment will be required. Silent women about their diseases can not. After a course of vaginal tablets, the symptoms disappear. However, after some time, the disease will develop again if the sexual partner does not undergo treatment.
Regarding the use of candles "Terzhinan" together with any other drugs, experts do not give any recommendations. Such negative effects that could occur with a combination of vaginal tablets with other drugs have not been identified.
There are practically no contraindications to the use of vaginal tablets. It is not recommended to use them only if it is known that there is an increased sensitivity to the components of the drug.
Purchase and storage of the drug
Candles "Terzhinan" can be purchased at any Russian pharmacy. No prescription required for purchase. The cost of the medicine is determined by the size of the package. A pack with 6 tablets costs about 430 rubles. A pack of 10 tablets is a little expensive. The price is about 500 rubles.
At home, the drug should be stored out of the reach of children. The recommended temperature regime is not higher than 25 degrees. The drug is suitable for 3 years from the date of manufacture. After this period, vaginal tablets cannot be used.
Reviews of women about "Terzhinan"
In general, reviews about vaginal tablets are positive. Women note the effectiveness of this drug, accessibility. Not too happy with the price. It seems high, but in fact the result in most cases is positive - all undesirable symptoms go away, the disease is cured.
Regarding the use of vaginal tablets, women give several recommendations:
- Candles must be removed very carefully so as not to break them. A soft strip of pills, also called a strip, is not very convenient. For accurate extraction of the medicine, it is best to take scissors. With the help of them, you can incise the strip and take out the pills without any problems.
- During treatment, pads are useful. The medicine after dissolving in the vagina flows a little.
Use vaginal tablets in accordance with the instructions. In reviews of candles "Terzhinan" people share far from positive experiences in self-healing. It does not lead to the expected result, it is harmful to health.
Be sure to consult a doctor for suspicious symptoms, because, in addition to Terzhinan, other drugs may be required. For example, one of the women said that with the help of this medicine she treated thrush. Terzhinan was appointed as a specialist. After the first application, the itching and discharge stopped. For a complete cure, a course of 10 days was carried out. The drug was used in accordance with the instructions. In a review of candles "Terzhinan" this woman noted that after treatment, the doctor additionally prescribed medications that help restore the natural microflora of the vagina.
What experts say about Terzhinan
Doctors note that vulvovaginitis of various etiologies, bacterial vaginosis are the most common diagnoses that gynecologists make to their patients. The listed conditions usually have such features as an erased clinical picture, polymicrobial etiology. In such cases, single drugs are not particularly effective. For this reason, experts say, candles "Terzhinan" in gynecology have gained immense popularity.
Conducted in the past studies have proved the high efficiency of vaginal tablets in the treatment of vulvovaginitis of various etiologies, bacterial vaginosis in non-pregnant and pregnant women. The effect of the drug was tested in undiluted and diluted form. Without dilution, Terzhinan was 100% effective in experiments with gram-negative microorganisms. With a large dilution (1: 100), only a small part of the microorganisms was resistant.
The sensitivity of gram-positive bacteria to the composition of candles "Terzhinan" in undiluted state in the experiments was equal to 74.1%. At a dilution of 1: 100, this indicator amounted to only 12.2%. However, experts note that in reality, a large dilution of the drug with vaginal secretions is impossible, therefore, the drug is considered effective.
Pimafucin
Long-term use of "Terzhinan" has shown that these vaginal tablets are very effective. Gynecologists very often prescribe this medicine to their patients. However, the drug is not suitable for everyone. Some women are not satisfied with the price, while others have an allergic reaction. Such situations are not hopeless, because “Terzhinan” has several analogues.
One of the similar drugs is Pimafucin in the form of vaginal suppositories. It is an antifungal agent. The active substance in its composition is natamycin (an antifungal polyene antibiotic of the macrolide group). Most pathogenic yeasts are sensitive to this component. The medicine is used in the treatment of vulvovaginal candidiasis.
The duration of therapy is 3-6 days. For convenience, the manufacturer of Pimafucin produces packs of 2 types - small with 3 tablets and large with 6 tablets. The price of the first package is about 260 rubles, and the price of the second is about 500 rubles.
Polygynax
Another analogue of Terzhinan suppositories is Polygynax in the form of vaginal capsules. This is a combined drug that is able to have antibacterial and antifungal effects. This effect is due to the presence of several active components in the composition. The drug includes neomycin sulfate, polymyxin B sulfate, nystatin.
Polygynax is prescribed for the treatment of various infectious and inflammatory diseases (nonspecific, fungal, mixed vaginitis, vulvovaginitis, cervicovaginitis), prevention of infectious complications (before operations, childbirth, intrauterine diagnostic procedures).
For preventive purposes, Polygynax is recommended to be used within 6 days. To treat a disease, you need a longer course of 12 days. In pharmacies, the medicine is sold in packs containing 6 and 12 tablets. The price is about 350 and 610 rubles.
Clotrimazole
It differs from Terzhinan suppositories in composition by analogue of Clotrimazole in the form of vaginal tablets. In this preparation, one active substance, bearing the same name. The component is effective against fungi, so Clotrimazole is classified as an antifungal.
Vaginal tablets have the following indications for use:
- Trichomonas vaginitis;
- vulvovaginal candidiasis;
- disease prevention (before gynecological procedures).
Clotrimazole, in comparison with Terzhinan, is a very cheap medicine. In pharmacies, vaginal tablets are sold in packs of 6 each. The price of the medicine is about 50 rubles.
Elzhina
Quite new is the drug Elzhina - vaginal tablets with anti-inflammatory, antifungal and antibacterial effects. The active substances in its composition are ornidazole, neomycin, prednisone, econazole. Such a medicine can help with bacterial vaginitis, vulvovaginitis caused by fungi of the genus Candida, and vaginitis caused by a mixed infection.
In contraindications, not only hypersensitivity to the components is listed, as in other drugs. You can not be treated "Elzhina" with organic diseases of the central nervous system, impaired hematopoiesis, pregnancy, breastfeeding. Caution should be used in alcoholism, impaired liver function.
Vaginal tablets are sold in packs of 6 and 9 pieces. Their cost is 340 and 470 rubles. respectively.
In conclusion, it is worth noting that the reviews about the use of Terzhinan suppositories and the recommendations of specialists do not allow to doubt that this drug is really effective and safe when properly prescribed and used. However, analogues can also have a positive effect. For each specific case, certain drugs should be selected. The right choice can only be made by a doctor.