The drug belongs to serotonin receptor agonists and is recommended for patients to eliminate headache attacks of various etiologies and intensities.
The drug "Sumamigren" is made in the form of tablets for oral administration.
The composition of the drug
According to the instructions for use with Sumumigren, the tablets are enteric coated, have a pink tint, oblong shape. Tablets are packaged in blisters in two and six pieces. In total, from one to two blisters. Each tablet contains fifty and one hundred milligrams of the active trace element - sumatritan, as well as a number of additional components:
- polysaccharide;
- starch;
- a salt of magnesium and stearic acid;
- lactose;
- dye;
- talc.
Indications
According to the instructions to Sumumigren, tablets are prescribed to patients over eighteen years old to eliminate migraine attacks with or without aura.
Contraindications
Before using the drug, you need to carefully read the instructions for use with Sumumigren 100 mg, since the capsules have a number of serious prohibitions on the use of:
- Coronary heart disease (myocardial damage caused by impaired blood flow in the coronary arteries).
- Myocardial infarction (a source of cardiac muscle ischemia, which develops as a result of acute damage to coronary microcirculation).
- Angina pectoris (a disease that is characterized by an unpleasant sensation of discomfort in the chest).
- Individual intolerance to the substances of the drug.
- Diseases of the blood vessels.
- An acute ischemic type of cerebral microcirculation caused by a decrease in blood circulation in the brain or spinal cord.
- Stroke (acute cerebrovascular accident causing damage and death of nerve cells).
- Arterial hypertension (increased blood pressure).
- Diseases of the liver and kidneys.
- Pregnancy.
- Lactation.
- The patient's age is up to eighteen and from 65 years.
How to use the drug?
According to the instructions, Sumumigren is taken orally, without chewing, washed down with water. The doctor prescribes the dosage of the drug individually for each patient, at the initial stage of treatment, fifty milligrams of the drug is enough once, then it can be increased to one hundred.
If the symptoms of migraine have not decreased, but rather intensified, it is recommended to stop therapy. In this situation, it is necessary to consult a medical specialist for the selection of another effective medication.
If the symptoms have decreased or completely disappeared, and after some time they have resumed again, then you can take another dose of the medicine, however, remember that the maximum amount of Sumumigren is three hundred milligrams.
Can I use Sumamigrain during pregnancy?
There is no scientific information on the use of pills for eliminating severe headache attacks in women during pregnancy, and it is not known how drug therapy can affect the development of an unborn child.
According to reviews and instructions to “Sumigamiren” it is known that the drug is not recommended for use during lactation, since the active substances are excreted in milk and can harm the baby.
If it is necessary to conduct drug therapy, lactation should be stopped, breastfeeding can be resumed only twenty-four hours after the drug is withdrawn.
Side effects
From the instructions to “Sumigamiren” it is known that when taking tablets in people with increased individual sensitivity to trace elements of the drug, negative reactions may develop, for example:
- Migraine
- Drowsiness.
- Paresthesia (a violation of sensitivity, which is characterized by a sharply developing sense of burning, tingling, crawling ants).
- Decreased joint sensitivity, tremor of limbs.
- Vegetative-vascular dystonia (a complex of functional disorders, which is based on a violation of the regulation of vascular tone by the autonomic nervous system).
- Flies before your eyes.
- Loss of vision.
- Visual impairment.
- Hypertension (bouts of high blood pressure).
- Heat in the head.
- Arrhythmia (heart rhythm failure).
- Bradycardia (lowering heart rate).
- Changes in electrocardiogram indicators.
- Myocardial infarction (one of the clinical forms of coronary heart disease, proceeding with the development of ischemic necrosis of the myocardial site, due to the absolute or relative insufficiency of its blood supply).
- Angina pectoris (a clinical syndrome characterized by sensation or discomfort in the chest).
- Raynaud's disease (a disease in which arterial blood supply to the hands or feet is disturbed).
- Nausea.
- Increased salivation.
- Vomiting
- Diarrhea.
- Colitis (an inflammatory disease of the colon mucosa).
- Pain in the abdomen.
- Dyspnea.
- Dryness.
- Myalgia (inflammation of muscle fibers).
- Apathy (a symptom expressed in indifference, indifference, in a detached attitude to what is happening around, in the absence of a desire for any activity).
- Foreign body sensation in the throat.
In rare situations, a patient may experience allergic reactions after consuming Sumumigren:
- an allergy characterized by the rapid onset of itchy blisters on the skin;
- skin rashes;
- irritation;
- swelling of the mucous membrane;
- anaphylaxis.
Overdose
With prolonged and improper use of the drug, the patient develops symptoms of poisoning, which are expressed in an increase in negative effects and intoxication.
If there are signs of an overdose with a medication, the patient must be put in a hospital where he will be monitored. If necessary, a symptomatic treatment will be given to the person.
Interaction
“Sumamigrain” cannot be used by patients together with “Ergotamine”, since this combination leads to prolonged convulsions of blood vessels, which leads to aggravation of attacks of severe headache. The drug "Sumygmiren" must be taken to the patient no earlier than a day after the cessation of therapy with drugs in the structure of which there is ergotamine.
Features
Pills can be prescribed to people only after making an accurate diagnosis, if there is doubt about whether a headache is considered a symptom of a migraine or not, then treatment with Sumumigrain is prohibited. For prevention, this drug is not prescribed.
Another prohibition on the start of therapy is arterial hypertension, a violation of the metabolism of trace elements, as well as liver and kidney diseases.
From the instructions for use and reviews of “Sumigamiren” it is known that people with increased sensitivity to medicines from the sulfanilamide group need to use pills carefully, since there is a high probability of severe allergic reactions.
With caution and under the supervision of a medical specialist, the medication should be used for people who suffer from epilepsy or to patients with a predisposition to epileptic seizures.
Since drowsiness and lethargy can develop in patients with the use of tablets, it is important at this time to refrain from driving and complicated machinery. This is reflected in the instructions for use.
Analogs of Sumamigren
The following medicines are substitute drugs:
- Sumatriptan
- Amigrenin.
- "Nalgesin."
- Migrepan.
- Imigran
- Rapimed.
- Sumumik.
- Sumarin.
- Sumig.
- Sumitran
Before replacing the prescribed drug with one of the analogues, a person must always consult a doctor.
Sumatriptan
The medication is in tablet form for oral administration. Capsules are film-coated, they have a rounded shape.
The active ingredient is sumatriptan, its concentration in one capsule can be fifty and one hundred milligrams. Also, its structure includes additional trace elements.
The active substance has a stimulating effect on the nerve endings, as a rule, only of blood vessels and brain matter. Due to this effect, narrowing of the dilated vessels can occur, as a result of which the severity of the pain syndrome decreases. The drug does not have a direct analgesic effect, therefore, it is not considered an anesthetic.
After taking the tablet orally, the main trace element of the drug is instantly and completely absorbed into the general bloodstream. It evenly spreads throughout all tissues, gets into the structures of the nervous system.
The active substance undergoes a transformation process mainly in the liver with the help of an enzymatic system of biologically active components that carry out the catabolism of monoamines to inactive decomposition products that are excreted in urine. The half-life is two and a half 2.5 hours. The cost of the drug is 170 rubles.
Amigrenin
Pills are medicines that are used to eliminate migraines. They contain an active trace element - sumatriptan, which belongs to the therapeutic group of serotonergic drugs. The active component has several effects, the result of which is considered to be a decrease in the intensity of headache attacks.
When using the tablet orally, the maximum content of the main substance in the blood is reached after 45 minutes. Sumatriptan freely passes through the blood-brain barrier, which gives it the ability to have a positive effect in brain tissue.
In addition, Amigrenin penetrates the body of an unborn baby during pregnancy and into milk during lactation. Sumatriptan is absorbed in the liver cells, its decomposition products are eliminated, as a rule, by the kidneys with urine. The elimination time of half of the total content in the body is approximately two hours. The cost of the drug varies from 150 to 250 rubles.
"Nalgesin"
The drug refers to non-steroidal medications that can inhibit inflammation in the body.
The drug has an analgesic, antipyretic effect, and also fights against inflammatory processes in the body. After use, "Nalgesin" is immediately absorbed in the digestive organs, and the analgesic effect occurs instantly.
The maximum concentration of the active substance in the blood reaches one or two hours after the first application. From the body, the drug is excreted using urine and feces.
In people who suffer from renal failure, there is an accumulation in the body of metabolic products of the active substance. To eliminate the risk of side effects from the digestive system, it is necessary to use the lowest pharmacological dose.
If, as a result of using Nalgesin, the fever and pain syndrome become more pronounced, then you need to consult a doctor.
Patients who suffer from bronchial asthma, as well as those with bleeding disorders, should use this medicine with the utmost care and only after the appointment of a medical specialist.
The medication must be prescribed with extreme caution to persons suffering from kidney and liver diseases. In the presence of cirrhosis, the concentration of the active trace element must be reduced. The cost of the drug varies from 150 to 500 rubles.
Storage conditions
Sumumigren can be bought at any pharmacy with a prescription. Keep the medicine in a cool, dry place, away from children. Shelf life is sixty months. The cost of the drug is 250 rubles per package.