Often, doctors include Phthalazole in the treatment regimen for intestinal infections. This is a broad-spectrum medicine that interferes with the activity of both gram-positive and gram-negative microorganisms. In addition, the drug has a bacteriostatic effect. The tool eliminates unpleasant symptoms as soon as possible, returning the patient's quality of life to the previous level.
Indications
According to the instructions for use, "Phthalazole" is a drug whose active ingredient is phthalyl sulfathiazole. Its task is the destruction of pathogenic microorganisms in the intestine. In addition, the composition of the drug is represented by the following excipients: talc, potato starch and calcium stearate.
"Phthalazole" - indications for use:
- dysentery (both acute and chronic);
- colitis and enterocolitis, the development of which is accompanied by severe diarrhea;
- shigellosis;
- gastroenteritis having a bacterial nature.
In addition, the drug is often prescribed to prevent complications after surgical interventions in the intestine.
Treatment with Phthalazole is very effective. This is due to the rapid improvement in the well-being of patients. In addition, pathogens do not become addicted to the drug.
According to the instructions for use, Phthalazole is effective against the following pathogens:
- streptococcus;
- pneumococcus;
- staphylococcus;
- meningococcus;
- gonococcus;
- intestinal, dysenteric, pseudomonas aeruginosa;
- protea;
- viruses that are causative agents of follicular conjunctivitis and trachoma.
It is forbidden to prescribe a medication for yourself. In many cases, the cause of intestinal upset may be a fungus in relation to which Phthalazole is ineffective. Against the background of taking the drug, the true picture of the disease is distorted, and therefore a lot of time is missed.
Contraindications
The drug is prescribed exclusively by the doctor based on the results of the diagnosis and taking into account the individual health characteristics of each patient. This is due to an impressive list of contraindications of the drug, in the presence of which it can harm health.
According to the instructions for use, "Phthalazole" is not prescribed to patients who have a history of:
- Individual intolerance to funds from the group of sulfonamides.
- An increased degree of sensitivity to any component in the composition.
- Pathology of the circulatory system (including iron deficiency anemia).
- Chronic kidney disease.
- Pathologies of the organs of the endocrine system (especially diffuse toxic goiter).
- Intestinal obstruction.
- Acute liver disease.
In addition, with caution, it is necessary to take the drug for children under the age of 3 years. Some manufacturers supplement the list of contraindications with pregnancy and lactation. But the drug is not absorbed into the bloodstream, it only enters the gastrointestinal tract. Thus, the drug does not penetrate the fetus during pregnancy. In addition, it is absent in breast milk.
Mode of application
The duration of treatment and the dosage of Phthalazole is calculated by the attending physician, taking into account the degree of sensitivity of the patient's intestinal microflora to this group of medicines.
If there are no prescriptions, the drug must be taken according to the instructions supplied by the manufacturer:
- The acute phase of the disease. In the first 2 days - 2 tablets every 4 hours. The next 2 days, the drug should be taken in the same amount. It is only necessary to increase the interval - up to 6 hours. On the 5th and 6th day, the drug should be taken twice a day. The dosage remains the same.
- In the event of a relapse of the disease, the course of administration must be repeated.
The maximum single dose of the drug for adults is 2 g (but not more than 7 g per day).
In children, the use of "Phthalazole" for diarrhea and other symptoms of intestinal infection is carried out according to the following scheme: three times a day, you must take a single dosage, calculated according to the formula 0.2 g per 1 kg of the child’s weight. The duration of treatment is 7 days (unless otherwise recommended by the pediatrician).
According to the instructions for use, "Phthalazole" slows down the synthesis of B vitamins. In this regard, at the same time, it is advisable to prescribe complexes containing them.
Against the background of taking the drug, there is no inhibition of psychomotor functions, and therefore, during treatment, the patient is allowed to drive potentially dangerous equipment and vehicles.
Side effects
Judging by the reviews, "Phthalazole" is well tolerated by patients. The occurrence of side effects in most cases is associated with an incorrectly calculated dosage and ignoring the existing contraindications.
Against the background of taking the drug, the following diseases and conditions may develop:
- feeling of depression, apathy;
- myocarditis;
- cyanosis of the skin;
- anemia;
- red blood cell destruction;
- stomatitis;
- damage to the oral cavity by fungi;
- nausea turning into vomiting;
- increased severity of diarrhea;
- allergic reactions, manifested by itching, rash, runny nose and sore throat.
In order to avoid the occurrence of side effects, it is also necessary to provide the doctor with information on taking other medications.
Drug interaction
"Phthalazole" is not combined with acids, epinephrine and hexamethylenetetramine. Against the background of its administration, the effectiveness of the latter decreases simultaneously with oxacillin. Significantly increases the risk of side effects when combined with thioacetazone, nitrofuran and chloramphenicol. The simultaneous administration of the drug with indirect anticoagulants enhances the effect of the latter.
Overdose
The main alarming symptom is a headache. The following conditions gradually develop:
- instability of the psychoemotional background;
- nausea turning into vomiting;
- severe diarrhea;
- damage to the oral mucosa;
- gastritis;
- cholecystitis;
- cholangitis;
- hepatitis;
- signs of ICD.
If an overdose occurs, the first aid is folic acid. It is necessary to consult a doctor to draw up a symptomatic treatment regimen.
Analogs
"Phthalazole" a few years ago was the only tool designed to eliminate diarrhea. Currently, the pharmaceutical market has many types of drugs with similar effects. Despite this, doctors still prefer Phthalazole to other drugs because of its availability to all segments of the population. The cost of one package, as a rule, does not exceed 100 rubles.
Modern analogues of Phthalazole:
- Bactrim
- "Biseptolum";
- "Berlocide";
- "Brifesceptol";
- "Co-trimoxazole";
- "Dvaseptol";
- Prednisolone
- Salofalk;
- Neonutrin
- Retinol;
- Pentas
- Salosinal;
- "Urbazon";
- "Metosulfabol";
- "Triamcinolone";
- Oriprim;
- Sulotrim;
- Ftazin;
- Sinersul
- "Sulgin";
- "Furazolidone."
It is important to understand that the question of replacing the drug is decided exclusively by the attending physician. This is due to the presence of a large number of contraindications for each of the above analogues. Their ignoring creates a threat to the patient’s health.
Reviews
"Phthalazole" is a broad-spectrum drug that destroys most pathogens of intestinal infections. Despite the huge number of modern analogues, the tool is still widely used. Judging by medical reviews, the drug has a high degree of effectiveness. Against the background of its intake, unpleasant symptoms are eliminated in a short time, the patients' well-being improves significantly.
As for patients, most of them speak positively about Phthalazole. At the same time, they especially note the fact that the drug has its healing effect in the shortest possible time. This is due to the fact that the active substance is not absorbed into the blood, but is sent directly to the lesion focus - the gastrointestinal tract. In addition, an important advantage is the cost of the drug, which makes it affordable for all segments of the population.
Finally
As a rule, doctors prescribe "Phthalazole" to combat the causative agents of intestinal infections. This is a broad-spectrum drug that interferes with the activity of not only gram-positive, but also gram-negative microorganisms. With strict adherence to the dosage regimen, the agent is not dangerous. Increasing the dosage or ignoring the existing contraindications significantly increases the risk of side effects.