Xalatan is a pharmaceutical pharmaceutical product. These are eye drops to lower intraocular pressure. In this form and is sold in pharmacies. The drug is very popular in the Russian market.
An agent is prescribed by the attending ophthalmologist to people with increased intraocular pressure, primary and secondary open-angle and pseudoexfoliation forms of glaucoma.
This is one of the most effective drugs to improve fluid outflow and reduce pressure. The drug is quite expensive. On sale are cheap analogues of "Xalatan".
Structure
- The main ingredient is latanoprost 0.05 mg.
- Additional substances: sodium chloride - 4.1 mg, sodium digiphosphate (monohydrate) - 4.6 mg, sodium hydrogen phosphate (anhydrous) - 4.74 mg, benzalkonium chloride - 0.2 mg, water for injection - 995 mg.
- Eye drops of 0.005% are sold in sterile 2.5 ml dropper bottles with a first opening control. Packed in cardboard boxes one or three pieces.
pharmachologic effect
The active substance latanoprost is a substitute for the natural prostaglandin F2a, which has a selective effect on the eye receptors. A decrease in ophthalmonus is observed several hours after the use of the drug and reaches its greatest effect in twelve hours.
Antiglaucoma action occurs due to the large outflow of fluid from the chambers of the eye. The drug does not affect the formation of intraocular fluid and vascular permeability. After use, the action of the product occurs within 24 hours.
Indications and contraindications
The drug "Xalatan" (analogues of the drug) is prescribed for the prevention and treatment of treatment of open-angle glaucoma and an increase in ophthalmotonus.
The tool should be used with great care before surgery for glaucoma.
Method and dose
It is prescribed to patients from 1 year of life (including the elderly) once a day, 1 drop in the evening locally in the eyes. Used as a component of mixed or monotherapy. Immediately after instillation, press on the inner corner of the lower eyelid for 1 minute. It is possible to use for 2 years with the subsequent replacement of the drug. Monitoring the level of intraocular pressure after 2-3 weeks, then after 3 months 1 time.
Side effects and overdose
The drug "Xalatan" (including analogues) has the following side effects:
- Local reaction: mild irritation, redness and inflammation of the mucous membrane of the eye may occur. This side effect is observed in 10% of people, only in 1% the severity is moderate. There may be pain, increased lacrimation, dryness, photophobia, decreased visual acuity, a change in pupil color, a change in eyelash growth, and swelling of the center of the retina.
- Respiratory system: difficulty breathing, narrowing of the lumen of the bronchi due to muscle contraction (bronchospasm).
- Nervous system: a sensation of pain in the head area or a fainting state (usually dizziness).
- Musculoskeletal system: joint and muscle pain.
- Skin: discoloration (blackening) of the eyelids, rashes on the skin, Lyell's syndrome (the appearance of blisters and erosion on the skin and mucous membranes).
- Infestations and infections: corneal inflammation caused by one or more types of herpes virus (herpetic keratitis).
- Other side effects: pain in the chest non-specific.
- People with diabetes with retinal damage (diabetic retinopathy) may experience blockage, peeling of the membrane or hemorrhage in the vitreous region when using this medication.
- In childhood, there is an increase in body temperature and inflammation of the mucous membrane of the nasopharynx.
- In patients with a clear lesion of the cornea, in exceptional cases, calcification is possible.
- If you accidentally use the drug inside, dizziness, pain in the gastrointestinal tract and nausea are possible. The treatment is symptomatic. Rinse the stomach.
These are the side effects that Xalatan (eye drops) can have. Analogs have side effects to no lesser extent.
Precautionary measures
Doctors do not recommend increasing the dose of the drug. This leads to a decrease in the effect of lowering intracranial pressure. It can be used with other ophthalmic drugs to reduce intraocular pressure.
If you missed a single instillation of the drug, then the next day, instill at the same time only one drop so that there are no unnecessary negative effects.
When using two types of drugs, the time interval between the introduction of drops should be 5-10 minutes. But it’s better not to mix drops, use only ones.
Mandatory removal of contact lenses before instillation is required, otherwise benzalkonium chloride is absorbed. Replacing the lens is possible after 20 minutes.
Treatment should continue if the color of the iris is changed, but under the supervision of an ophthalmologist. The appointment of "Xalatan" can be canceled, but, as a rule, increased pigmentation is not accompanied by pathological changes.
When prescribing treatment in one eye, there is a chance of developing unequal color of the iris of the left and right eye (heterochromia).
“Xalatan” (analogues also) is carefully prescribed to people who drive vehicles and sophisticated equipment, since there is a likelihood of a quick-passing feeling of the veil in front of the eyes. It is better to install the drug outside of a hazardous activity. There is a chance of temporary darkening of the eyelids.
The tool can cause a change in growth, color of eyelashes and vellus hair. After drug withdrawal, the effect passes by itself. During pregnancy and lactation, “Xalatan” (analogues also) is prescribed with caution.
During use, you can not touch the bottle to the eyes and various objects. With great caution, they are prescribed for congenital or acquired absence of the lens (aphakia) and inflammation of the choroid (uveitis).
Do not prescribe a simultaneous administration with drops containing thiomersal. Strengthening the action of "Xalatan" while taking pilocarpine and timolol.
Terms and conditions of storage
Store the drug in a cold, protected from light and inaccessible to children. Shelf life is 3 years. If the bottle has already been opened, it can be stored for 4 weeks, avoiding exposure to the solution at high temperatures (above 25 degrees Celsius). It is released according to the prescription form.
Xalatan Drops: Analogs
Xalatan substitutes are used if it is not in the pharmacy, if you get used to this drug, if side symptoms are found:
- "Cosopt" (Netherlands) - 800-900 rubles.
- Trusopt (France, USA) - 450-470 rubles.
- "Travatan" (Belgium) - 660-700 rubles.
- Azopt (Belgium, USA) - 800 rubles.
- Azarga (Belgium) - 980 rubles.
- Fotil (Finland) - 300-350 rubles.
- "Betoptic" (Belgium) - 310-380 rubles.
- Glauprost (Romania) - 1440-1500 rubles.
"Xalatan" Russian analogues has the following:
- Ksalakom (Russia) - 700-900 rubles.
- Glaumax (Russia, Estonia) - 470-550 rubles.
- Xalatamax (Russia, Croatia) - 450-550 rubles.
For the drug "Xalatan" analogues are cheaper you can find the following:
- Arutimol (Germany) - 46-72 rubles.
- Okamed (India, Germany) - 52-79 rubles.
- Timolol (Finland, Germany) - 20-45 rubles.
Patient Reviews
Mostly reviews about the drug are positive. Most often there are complaints of side effects of a local nature (redness, pain, tearing and dryness). The most rare side effects from the respiratory system. If the above complications appear, you should consult your doctor to replace the drug.
To date, they began to use drops not for their intended purpose, but for the growth of eyelashes. For these purposes, the analogue of “Xalatan” in Russia “Pilocarpine” is used because of the low cost of the latter.