Antibiotics, which are often used in the practice of treating diseases of various etiologies, are used only if necessary. These drugs are not recommended for prevention (in most cases), as well as in the treatment of diseases caused by viruses. If, nevertheless, a need arose in this group of drugs, it is worthwhile to study the instructions for the drug before use, since each of them affects only certain pathogens.
So, Cefazolin instruction advises for infectious and inflammatory diseases of the respiratory tract, skin, joints, pelvic organs, infections after surgery or burns, etc. This drug acts on some gram-positive and gram-negative microorganisms. For the drug "Cefazolin" indications for use may be such as urinary tract infections, gonorrhea, syphilis.
Since this antibiotic is poorly absorbed into the gastrointestinal tract, it is administered intramuscularly or intravenously. After the drug is administered, its maximum dose in the blood is observed after 1-2 hours.
Contraindications to this tool are the age of the newborn under 1 month, since the safety of the use of the drug during this period and the sensitivity to the components that are contained are not fully established. With caution, the drug is prescribed to patients with intestinal diseases (including colitis) and renal failure. During the expectation of a child, the medication is prescribed only if the benefit for the woman exceeds the risk to the fetus. If a woman is breastfeeding, and treatment is necessary, the question is raised about the completion of lactation.
Since the effect of the antibiotic in each case is individual, for those who use Cefazolin for treatment, the dosage is determined by the doctor and depends on the severity of the disease, the patient's age, the sensitivity of the pathogen to the drug and other factors. So, in most cases, children are recommended a volume of 20-50 mg per kilogram of body weight per day. In severe cases, it can be increased to 100 mg. For adults, the dose should not exceed 6 g per day, usually from 1 to 4 g is prescribed. The duration of the course can vary from 7 to 10 days.
For intramuscular administration of the drug “Cefazolin”, the instruction recommends dissolving it in lidocaine or water for injection. 4 ml of liquid are taken per 1 g of powder. For intravenous injections and children up to a year, lidocaine is not taken as a solvent. When diluted, the vial is well shaken until the powder is completely mixed. Liquids are used only transparent or colorless, ready-made solutions are stored in a cool (2 to 8 degrees) darkened place for no more than a day, after which it is no longer possible to use them for injection.
When taking the medicine "Cefazolin", the instruction notes the possibility of side effects. They can be expressed in allergic reactions, gastrointestinal disorders. With prolonged antibiotic therapy, dysbiosis or superinfection may occur, caused by strains that are resistant to the drug. In addition, the development of candidiasis, convulsions, vaginitis, chest pain is possible.
In case of an overdose of the drug “Cefazolin”, the instruction notes the occurrence of the following symptoms: dizziness, inflammation at the injection site, seizures, headache. Treatment is indicated symptomatically, while it is important to monitor the patient's laboratory parameters.
It is not recommended to simultaneously carry out therapy with anticoagulants, diuretics, aminoglycosides, since the risk of the development of the toxic effect of the drugs increases significantly. It is necessary to exclude the use of alcohol when using drugs.