"Kombilipen": application, instruction, analogues

In the age of the Internet, almost everyone has heard about the health benefits of B vitamins. When they are deficient, the body works "to wear": the nervous system suffers, the digestive system decreases, a person suffers from problems with the condition of the skin and hair. If there is a risk of deficiency of B vitamins, you should choose a quality drug to eliminate it as soon as possible. Instructions for use and reviews of Kombilipen injections indicate that this drug allows you to quickly get rid of the main symptoms of a deficiency of vitamins B ₁ , B ₆ and B ₁₂ .

The composition and form of the drug

The release form of the drug is tablets and a solution for intramuscular injection. The main active ingredient is a combination of B vitamins, in particular thiamine, pyridoxine and cyanocobalamin. Due to this composition, one of the most popular drugs for neurological pathologies is Combibipen. Its use is justified for a variety of lesions of the nervous system, as well as for problems with skin, hair, and digestion. The composition is thought out thoroughly: cyanocobalamin and pyridoxine contribute to the absorption of thiamine, as a result of which the maximum therapeutic effect is achieved.

The injection form of the drug for injection also contains lidocaine (an anesthetic component), so the injections do not cause such discomfort as regular injections of vitamins separately. The patient can inject himself. In addition, Combilipen can also be entered in the treatment room. Reviews about the application report that many patients still give themselves injections themselves, instead of visiting the clinic daily. This is a simple and painless procedure that requires minimal skills and does not bring discomfort to the patient.

The dosage form of the drug "Combilipen Tabs" has the form of biconvex rounded white tablets, located in standard blisters of 15 pieces. They should be taken as a whole, without chewing. It is optimal to take after meals, since when taken on an empty stomach, many patients complain of discomfort in the epigastric region.

Pharmacological action of the drug

Instructions for use and reviews of injections "Combilipen" report that the drug has the following pharmacological action:

• with regular use, restores the myelin sheath of nerve fibers, which generally improves the conductivity and functioning of the central nervous system;
• normalizes the production of neurotransmitters that are responsible for many processes in the human body: maintaining high performance and good mood, normal libido, metabolic rate, reaction rate to stimuli and much more;
• normalizes the transmission rate of nerve impulses;
• partially restores nerve cells damaged due to intoxication (this is especially true for patients with chronic alcoholism and drug addiction);
• helps to reduce pain provoked by a malfunction of peripheral NS;
• contributes to weight loss, as it normalizes the metabolism of fats, proteins and carbohydrates (provided that the patient has no other serious metabolic diseases);
• increases working capacity and endurance;
• normalizes sleep, helps to increase the psycho-emotional stability of a person during high stress loads.

In the reviews, patients who underwent several courses of therapy with the drug note not only relief of health and relief from neurological pain, but also other changes. In particular, after the Combilipene course, a person becomes more collected, efficient, gets enough sleep, sleeplessness goes away and sleep phases normalize. Such a positive effect is easily explained: the functioning of the central nervous system is restored, which is manifested not only in getting rid of pain and discomfort of a neurological nature, but also for normalizing the psychoemotional background.

The use of each vitamin in the composition of "Combilipene"

Let us consider in more detail each component of the Combilipen composition:

1. Thiamine, or vitamin B _1, is the main ingredient of the drug. This trace element is necessary for the normal functioning of the nervous system. With its deficiency, a person can suffer from increased irritability, pain of a neurological nature, migraine with and without aura, manifestations of vegetative-vascular dystonia, decreased performance, problems with interaction with others. Also, patients with a vitamin B ₁ deficiency in their blood often suffer from sleep problems. Thiamine is necessary for normal intestinal motility. The intake of high doses of this vitamin is often able to relieve constipation.
2. Pyridoxine, or vitamin B ₆ , is essential for healthy skin and hair. It also contributes to the preservation of nerve cells during toxic loads - for example, with regular poisoning with alcohol or drugs. In case of a hangover syndrome, it is also recommended to use Combilipen. The use of the drug for acne or problems with rashes on the skin of an unclear etiology is justified precisely because of the presence of pyridoxine in the composition.
3. Cyanocobalamin, or vitamin B ₁₂ , is also part of the drug. This trace element is necessary to maintain a healthy immunity, high performance and good mood. It normalizes the metabolism, when used in high doses, it affects the composition of the blood. With deficiency, cobalamin anemia can develop.

Indications for use

"Combibipen" injections are effective in the following diseases and conditions:

• trigeminal neuralgia;
• polyneuropathy of alcoholic etiology;
• diabetic polyneuropathy;
• pain provoked by neuralgic diseases;
• inflammation of the facial nerve;
• osteochondrosis;
• cervicobrachial syndrome.

Both injections and tablets have the same indications for use. The use of Combilipen tablets is justified if the patient does not have diseases of the digestive tract or for one reason or another is not able to make injections. It is proved that B vitamins may not be fully absorbed when passing through the organs of digestive waste.

Indications for the use of Kombilipen injections are different and may differ from those listed in the instructions. Often, dermatologists prescribe an injection course for patients who complain of alopecia (hair loss) and skin problems. Although these indications are not listed in the instructions, the drug has proven effective in these cases.

Contraindications to the use of the drug

Instructions for use for intramuscular injections "Combilipen" reports that the drug has the following contraindications for use:

• heart failure;
• intolerance to B vitamins;
• period of pregnancy and breastfeeding.

The tablet form of the drug should be used with caution to persons who are prone to allergic reactions. Typically, B vitamins are well tolerated, but they can also provoke quite serious side effects, among which allergic reactions come first.

Feasible side effects

Alas, taking any drug can cause side effects, with the exception of Combilipen. Instructions for use for intramuscular injections reports that the introduction of the drug may be accompanied by the following side effects:

• acne (in the first days of taking pills, the situation with the skin condition may worsen, but in the long term the drug helps to accelerate the regeneration of the skin);
• nausea, especially if you take a few tablets on an empty stomach;
• hyperhidrosis, that is, increased sweating, can be observed with frequent use of high dosages;
• tachycardia and arrhythmia, as well as pressure surges in individuals who suffer from chronic diseases of the cardiovascular system.

If the patient observes any of these symptoms, it is best to immediately stop taking it.

Any drug can cause malaise, not an exception, and "Combilipen". Instructions for use for injections (including drug analogues) report that with intramuscular administration, side effects develop less frequently than with oral administration of the drug. However, patient reviews do not report any relationship between the development of side effects and the choice of form of release of the drug.

Dosage and duration of administration

Instructions for use for injections "Combilipen" (intramuscularly) reports that the course should be at least 10 days, one injection per day. This is the minimum period, if you shorten it, then you may not feel the therapeutic effect of the drug. Instructions for use and reviews of the tablets "Combilipen" report that with oral administration, the course lasts an average of 30 days. It can be extended by decision of the treating neuropathologist.

The reviews of the people who took it indicate that in some cases the neuropathologist can prescribe a regular appointment for several months or until the symptoms of the underlying disease become less pronounced. As a rule, one or two tablets for adults and one tablet for children are prescribed per day.

Many neuropathologists advise their patients to inject Combilipen injections intramuscularly. Instructions for use informs that in this case, the drug enters the bloodstream as quickly as possible, as a result, all vitamins are absorbed to the maximum extent. When taken orally, part of thiamine and pyridoxine may not be absorbed, which reduces the effectiveness of therapy. In addition, judging by the reviews of patients, people with chronic diseases of the gastrointestinal tract may experience an undesirable exacerbation, especially when using Combiben Tab on an empty stomach. If the patient insists on taking exactly the tablet form of the drug, but he has gastritis or peptic ulcer, then you should take the pill after a light breakfast.

"Combilipen": application in home cosmetology

In addition to the treatment of neurological disorders, the drug is actively used by women who take care of themselves. It's no secret that B vitamins help accelerate the regeneration of the skin, and also improve the quality of hair. Moreover, this effect is achieved both with external and internal reception.

In particular, some girls add the contents of the Combilipen ampoule to face masks and hair balms. Before trying such a recipe on yourself, you should make sure that there is no allergic reaction to the drug. If the composition is overly concentrated, itchy skin and unwanted rashes may be observed. Therefore, before applying the mask to the face, you should test the skin reaction on the inner bend of the elbow.

Reviews of girls who add the contents of ampoules to hair masks report that the hair becomes shiny and magnificent. Hair falls out less and grow faster if you use such masks on a regular basis.

Drug Interactions with Other Drugs

If the patient is undergoing treatment with Levodopa, then a parallel intake of B vitamins can provoke insufficient therapeutic effect of pyridoxine.

Parallel administration of Combibipen and analogues is prohibited (instructions for use especially focus on this) with substances that have an oxidation-reduction effect on the body. These are iodide, mercury chloride, tannic acid, acetate, carbonate.

It is also forbidden to combine the drug and its analogues with drugs, which include sodium phenobarbital, riboflavin, dextrose, metabisulfite.

In contact with copper, thiamine tends to break down very quickly. Therefore, you should not use multivitamins or foods rich in this mineral against the background of the Combilipen treatment course. Thiamine inactivation also occurs when the pH exceeds 3.

Reception of alcoholic beverages is possible in parallel with the course of the drug. But it should be remembered: the effect of the drug is aimed at restoring the nervous tissue, while alcohol destroys neurons, contributing to their multiple death. So even small dosages of alcohol negate the therapeutic effect of both tablets and injections.

Use of the drug during pregnancy and lactation

The components that make up the drug in question are able to pass through the placenta and into breast milk, so its use is not recommended during this period. "Combilipen" can provoke undesirable fetal developmental pathologies. To say with accuracy that the consequences for the fetus will be sad, not a single doctor will undertake, however, to minimize the possible negative impact on the child, it is better to refuse to use the drug.

If the expectant mother aggravated neurological diseases during pregnancy, which is a direct indication for the use of Combilimen and its analogues, then you should pay attention to alternative medicine methods to alleviate the symptoms - such as massage, compresses, swimming. You should consult with a neurologist and choose a safe method for yourself to get rid of negative symptoms.

List of effective analogues of the drug

Often patients are interested in what to choose: a drug of foreign or domestic production, injections or pills, Combilipen or analogues? Instructions for use with most drugs, which contain B vitamins, argue for the use of a particular drug. However, the most correct appointment can be expected only from a neuropathologist who is aware of the individual characteristics of the patient, his diagnosis and the degree of pain. As mentioned above, the drug is prescribed not only by neurologists, but also endocrinologists, dermatologists. The drug is effective in many diseases, as evidenced by the instructions for use with Combilipene. Reviews about the analogues of the drug report that these funds are often no worse, and sometimes even better.

List of the most popular analogues:

1. Tetravit is a tablet preparation, which, in addition to thiamine, includes nicotinic acid and riboflavin. This drug can only be taken orally, there are no other forms of release. Since nicotinic acid is also part of the composition, the intake improves blood circulation in the upper body. The minus of “Tetravita”, compared with “Combilipene”, is that the former does not contain pyridoxine and cyanocobalamin. So with severe neurological disorders, the reception may not live up to expectations.
2. "Neuromultivitis" is an almost complete analogue of "Combibipene", the composition also includes thiamine, pyridoxine and cyanocobalamin. Indications for use are similar. "Neuromultivitis" is available in the form of tablets and ampoules for injection. The main purpose of the reception is the regeneration of nerve tissue, as well as the acceleration of metabolic processes. In this, the drug is very similar to Combilipen. Instructions for use and reviews of analogues of those patients who have tested both drugs on themselves allow us to conclude that Neuromultivit has exactly the same effect as Combilipen, but it costs significantly more.
   
3. Milgamma is produced both in the form of tablets and as a liquid for intramuscular administration. The composition of the drug in ampoules includes thiamine, pyridoxine, vitamin B ₁₂ and lidocaine, so that we can talk about a completely identical composition. Patient reviews indicate that the therapeutic effect of the drugs is also identical. The difference in cost is significant: Milgamma costs twice as much as Combilipen, so most patients prefer to use the latter. If in doubt, which drug to choose, it is worth consulting a neurologist.