Arbidol, the instruction of which is given here, is available in yellow capsules. Each of the capsules of this drug contains a powder, the color of which can vary from white to greenish-yellow or cream shades.
Structure
Active substance:
- methylphenylthiomethyl-dimethylaminomethyl-hydroxybromindole carboxylic acid ethyl ester - 50/100 mg (in 1 capsule of preparation No. 3 and No. 1, respectively).
Excipients:
- colloidal silicon dioxide ;
- potato starch;
- crospovidone;
- calcium stearate.
Pharmacological action of the drug arbidol
The instruction says that arbidol belongs to antiviral drugs, as well as to the group of immunomodulators. The drug has an antiviral effect, including antiviral effects manifested against influenza A and B, and against SARS.
The mechanism of action of the drug is as follows - by inhibiting the connection of the lipid membrane together with the cell membrane, the drug prevents the penetration of the virus into the cells. In addition, arbidol induces interferon, thereby stimulating humoral and cellular immunity, and it also enhances the phagocytic effect of macrophages and increases the body's overall ability to resist infection.
Arbidol is able to reduce the incidence of complications that cause viral and bacterial infections. Its therapeutic effectiveness is manifested, first of all, in the ability to reduce the general intoxication of the body and remove the clinical manifestations of the disease, thereby significantly reducing the duration of the disease, and all this thanks to the drug arbidol. The instruction shortened, official annotation includes more pharmacological actions of the drug.
Pharmacokinetics
Arbidol is quite rapidly absorbed into tissues and organs, its maximum concentration in the blood occurs within about an hour.
Arbidol is metabolized, like most other drugs, in the liver, its half-life is about 20 hours. The drug is excreted through bile (about 38%) and through the kidneys (less than 0.2%), and 40% of the total amount of the drug is excreted from the body unchanged. About 90% of the total dose taken is excreted within one day.
Indications for the treatment and prevention of arbidol
The method of use of the drug is oral, it must be taken only on an empty stomach. Arbidol is suitable not only for the treatment of diseases, but also for different degrees of prevention, for example, it is possible to use different doses of the drug for general prevention of the disease or for its prevention after contact with an infected patient.
Diseases that the drug can cure:
- flu;
- ARVI;
- TORSO;
- acute and chronic bronchitis;
- acute and chronic pneumonia;
- herpes, including recurrent;
- secondary immunodeficiencies;
- intestinal infections, rotoviruses;
- postoperative infections.
Side effects
Arbidol does not show any side effects, except for an individual allergy to its components. The drug is absolutely safe.
In addition, studies have shown that arbidol does not have any negative effects on the human central nervous system, so it can be used even by healthy people in order to prevent colds and infectious diseases.
Arbidol can also be taken during strong physical exertion and during the management or operation of complex technical mechanisms, because it does not cause any negative consequences.
Contraindications
The drug is not recommended for children under 2 years of age.
Drug Interactions Arbidol
The instruction says that the effectiveness of the drug does not change with the use of other drugs.