In the article, we consider the instructions and analogues for the Bicyclol preparation.
A significant part of everyday life is regular snacking, replacing a healthy breakfast, dinner or lunch, an unhealthy lifestyle, and constant stress, including alcohol abuse and smoking, which leads to digestive problems.
When a particular organ of the gastrointestinal tract fails, the whole human body suffers, since it loses the substances it needs. Therefore, if there are any signs of a gastrointestinal tract pathology, for example, flatulence or abdominal pain, it is necessary to go to a medical institution.
In order to cure gastrointestinal diseases, the specialist prescribes a complex treatment, which includes diet, exercise therapy and medication. One of the latter may be a drug such as Bicyclol.
Composition and form of release
According to the instructions for Bicyclol, the dosage form of the drug is round tablets, convex on both sides, white or almost white in color (there are nine pieces in blister packs, two packs in a cardboard box). The active substance is bicyclol, 25 milligrams in one tablet. Auxiliary components are as follows: starch paste 10%, sodium carboxymethyl starch, corn starch, magnesium stearate.
Indications
According to the instructions for use, Bicyclol is prescribed in the following cases:
- if the patient has chronic hepatitis C and B (if there is excessive activity of liver enzymes);
- patients whose treatment with antiviral agents did not produce the desired effect);
- if a person has been diagnosed with toxic (drug, drug and alcohol) forms of hepatitis;
- if the patient has non-alcoholic steatohepatitis.
In addition, the drug can be prescribed if the patient has fatty degeneration of the liver and cirrhosis.
Mode of application
In accordance with the instructions "Bicyclol" must be taken orally and washed down with water. Chewing tablets or using them in the form of powdered powder is prohibited. If there are problems with swallowing the pill in its entirety, the specialist needs to replace the drug with another suitable for the treatment of pathology. Most often, adults are prescribed medication three times a day in the amount of 25-50 milligrams.
For the treatment of non-viral hepatitis, predominantly a specialist prescribes the drug "Bicyclol" at 25 milligrams. Reception is divided into three times. If the patient does not have positive dynamics, after a month or two, the dosage can be increased to 50 milligrams. The number of receptions does not change.
For the treatment of viral hepatitis B and C, which are in a chronic stage, the drug is prescribed three times a day in an amount of 50 milligrams.
The medicine should be taken one hour after a meal. Treatment should be continued for six months. If a specialist considers it necessary, therapy can be resumed after a month break.
A detailed description of Bicyclol is indicated in the instructions.
Combination of drugs
Efficiency decreases with simultaneous use with Lamivudine and other nucleoside inhibitors. In other situations, depending on the effect on the transaminase activity of other drugs:
- Antibiotics (semisynthetic, synthetic penicillins and fluoroquinolones, antifungal medications, antiviral drugs, synthetic immunomodulators of origin) - increase the concentration of Bicyclol in hepatocytes - reduce the average daily dose.
- Immunosuppressants, antiepileptic and anticonvulsants, antipsychotics - reduce the concentration - increase the average daily dosage, stop taking this drug and wait for its content to drop, refuse the drug until treatment with another medication is completed.
As the instruction indicates, “Bicyclol” helps to slow down the decomposition of aldehydes to acetic acid - the toxicity of alcoholic beverages increases, respectively, alcohol reduces its effectiveness.
Side effects
Most often, Bicyclol does not cause side effects, but in isolated situations, the following manifestations can be recorded:
- drowsiness, headaches, excessive fatigue, anxiety, dizziness, fear and depression;
- menstrual defects, alopecia;
- bloating, nausea, flatulence, a feeling of pain in the stomach, the urge to vomit, diarrhea;
- itchy skin, redness of the epidermis, urticaria, skin rash, runny nose, stuffy nose, swelling, Quincke's edema and other allergic manifestations.
According to the instructions for use and reviews of Bicyclol, side effects go away on their own after stopping the drug or reducing the dosage. If this does not happen, you need to contact a medical institution and consult.
Overdose
In accordance with the instructions for Bicyclol, if you exceed the maximum allowable daily dose of 150 milligrams, 2.5-3 times, there will be no intoxication and other dangerous manifestations, in addition to allergic. Some patients report the appearance of such side effects:
- slight dizziness;
- dyspepsia;
- insomnia;
- rashes on the skin, similar in symptoms to urticaria;
- brief defocusing of attention.
Special instructions for the use of the drug
During treatment, it is necessary to periodically monitor the performance of the liver, as well as the clinical picture of the disease in accordance with the standards for monitoring the corresponding disease.
In patients who have concomitant gastrointestinal pathologies, for example, cholecystitis, gastritis, pancreatitis, the use of “Bicyclol” can be accompanied by a significant clinically significant increase in the activity of GGTP, ALP, and AST. In this regard, the treatment of such patients should be carried out very carefully, additionally monitoring the functional values ​​of the hepatobiliary system.
There was no study of the drug "Bicyclol" on the ability to drive vehicles and engage in other activities that require a high concentration of attention, the speed of psychomotor reactions, and are potentially dangerous. During treatment with medication, you need to be careful when driving and the types of activities mentioned above, since there is the possibility of dizziness.
What else does the instruction for the Bicyclol preparation tell us?
Lactation and pregnancy
The effect of Bicyclol on the condition of the newborn and fetal development has not been investigated, which means that the manufacturer considers lactation and pregnancy to be contraindications. Judging by the type of chemical compound of the drug (lignan), the medicine can reduce the amount of fluid that passes through the placenta, as well as the acidity of the ovum, that is, the fragility of the vessels and bones of the unborn baby. Malignant formations in the liver and leukemia may occur. The drug passes into breast milk.
This is confirmed by the instruction for Bicyclol. A photo of the drug is presented above.
Use for impaired liver and kidney function
The drug contributes to the formation of solid formations. If the use is prolonged, bilirubin may increase. It is advisable to postpone treatment when diagnosing:
- pyelonephritis and acute cholecystitis;
- gallstone or urolithiasis;
- kidney failure - at the terminal stage, no more than 75 milligrams per day can be used along with nephroprotectors.
Terms and conditions of storage of medication
The drug should be stored in a place inaccessible to children and dry, at a temperature of 8-25 ° C, for three years. After the expiration date of the drug indicated on the pack, it is forbidden to use.
The instructions for use with Bicyclol are not indicated. Consider them below.
Analogs of this drug
The drug has the following analogues: Uniliv, Antral, Essliver, Glutarsol, Enerliv, Essential Fort N, Essel forte, Apcosul, Citrarginine, Hepel, “ Esavit ”,“ Karsil ”,“ Phospholip ”,“ Darsil ”,“ Thiotriazolin ”,“ Legalon ”,“ Galstena ”,“ Triliv ”,“ Bondjigar ”,“ Simepar ”,“ Gepadif ”,“ Silimarol ”,“ Livolact ” , “Sirepar”, “Brenziale Forte”, “Silisem”, “Gepar”, “Silibor”, “Esavit”, “Silimarin”, “Vimliv”, “Ornitoks”, “Lesfal”, “Remaksol”, “Phosphogliv”, “Lioliv”, “Hepa-Merz”, “Livenziale”, “Liv-52”, “Livolact”, “Hepel N”, “Lecithin”, “Glut rgin "," Gepabene ".
"Hepa-Merz" is a hypoammonia medication. It has a detoxifying effect, it reduces the increased level of ammonia in the body, in particular, with liver pathologies.
It is used for acute and chronic liver diseases that are accompanied by hyperammonemia; hepatic encephalopathy (latent or severe), including in the complex treatment of impaired consciousness (precom and coma); steatoses and steatohepatitis of various origins; for parenteral nutrition in people with protein deficiency.
Essentiale is a hepatoprotector. Effective when the metabolic activity of the liver is impaired, they provide the intake of high-energy phospholipids ready for assimilation.
They normalize the liver and the enzymatic activity of organ cells, provide stabilization of the physico-chemical properties of bile, improve the regeneration of liver cells, reduce energy costs, and facilitate the metabolism of neutral fats and cholesterol.
Among the listed analogues there are cheaper ones, however, only a pharmacist or doctor can make a replacement.
Reviews
Patients predominantly report improvement in general condition, starting from the first week of treatment. Experts say that AST and transaminase levels are normalizing - the load on healthy hepatocytes decreases. Specialists and patients highlight the advantages of Bicyclol, such as:
- the absence of obvious side effects as with standard treatment regimens: fever above 39, persistent severe nausea, short-term loss of consciousness, headaches, exhaustion of the body and aching in the bones;
- minimum lifestyle and nutritional requirements;
- relatively affordable price;
- ease of use.
Many patients are mistrustful of this drug, since it is hepatoprotective. In addition, some people are scared by the price of the drug.
We reviewed the Bicyclol tool and instructions.