In the article, we consider the use of Bicyclol, the instructions for use, price, reviews and analogues.
The modern rhythm of life makes you eat irregularly, with a lot of snacks. This has become the norm today, especially for office staff. Improper diet and lifestyle, constant exposure to stress, as well as excessive alcohol consumption and other bad habits like smoking lead to digestive disorders. When a malfunction occurs in one or several organs of the gastrointestinal tract, the work of the whole organism stray from the normal rhythm, since it ceases to receive the necessary nutrients in the right amount.
For this reason, do not postpone going to the doctor if flatulence or soreness in the abdomen occurs. In order to prescribe adequate treatment, a person needs to undergo a thorough examination. Therapy includes both taking various drugs, and therapeutic exercises, following a special diet. One of the popular drugs prescribed for problems with the gastrointestinal tract is Bicyclol. Reviews about the drug are abundant.
Composition and form of release
It is produced in a single form - round tablets, biconvex, white. Tablets of 9 pieces are packaged in one blister of 18 in one package. The active component of the drug is bicyclol, the content of which in one tablet is 25 mg. The tablets also include auxiliary components, namely corn starch, magnesium stearate, sodium carboxymethyl starch.
Indications
The drug is a hepatoprotector and has a positive effect on the condition of the liver. According to the instructions, Bicyclol is prescribed for the following indications:
- The presence in the patient's history of hepatitis C and B virus type, proceeding in a chronic form. This is especially true of the situation when there is an increased activity of liver enzymes.
- If antiviral therapy does not give a positive result.
- Hepatitis toxic type due to poisoning by alcohol, drugs or drugs.
- A non-alcoholic variety of steatohepatitis.
- Fatty degeneration of the liver, as well as cirrhosis.
According to reviews, the price of Bicyclol is quite reasonable.
Application and dosage
The instruction prescribes taking the tablets orally with a sufficient amount of water. Do not grind tablets or chew them. If the patient cannot swallow the tablets due to circumstances, he is prescribed other drugs from the category of hepatoprotectors in a convenient form of release.
The standard dosing schedule involves the use of Bicyclol 25-50 mg three times a day. In the treatment of hepatitis of non-viral etiology, the doctor prescribes 25 mg up to three times a day. If there is no positive result from therapy after several months of administration, the dosage can be doubled and taken at 50 mg. Chronic viral hepatitis will require 50 mg three times a day.
Bicyclol is taken one hour after a meal. Therapy should last at least six months. If necessary, a second course can be started after a month's break. This confirms the instructions for use for the Bicyclol product. Price and reviews will be presented below.
Combination with other drugs
The therapeutic effect decreases with the simultaneous administration of the drug with Lamivudine and other drugs from the category of nucleoside inhibitors. In addition, the following nuances should be taken into account while taking the drug with other medicines:
- The concentration of bicyclol in hepatocytes increases due to a combination with antibacterial drugs from the group of fluoroquinolones, synthetic and semisynthetic penicillins, as well as antifungal agents, antiviral drugs and synthetic immunomodulators. To avoid adverse reactions, you should reduce the daily dosage of Bicyclol.
- The concentration of the active component of the drug is reduced in combination with immunosuppressants, anticonvulsants and antiepileptic drugs, as well as antipsychotics. In this case, it is recommended to increase the daily dosage of Bicyclol or to refuse to take it in favor of other drugs that are better combined with the indicated groups of medicines.
The medication, according to the instructions, provokes the breakdown of aldehydes to obtain acetic acid, so the toxic effect of alcohol on the body is enhanced, and the effectiveness of the drug is significantly reduced. For this reason, it is not recommended to combine the intake of tablets with the use of alcoholic beverages.
Adverse reactions
In most cases, the drug "Bicyclol", according to reviews, is well accepted by patients and does not lead to the development of undesirable reactions. However, in some situations, the following symptoms may occur:
- Headache.
- Drowsiness.
- Fatigue.
- Dizziness.
- Anxiety.
- Feeling of fear and depression.
- Violation of the cycle of menstruation, alopecia.
- Nausea, flatulence, bloating.
- Soreness in the stomach, vomiting, diarrhea.
- Redness of the skin, itching, urticaria, allergic runny nose and nasal congestion, swelling, Quincke edema, etc.
Patients and doctors indicate that such symptoms disappear on their own after reducing the dosage of the drug or refusing to take it. However, if this did not happen, we can talk about intoxication due to overdose. This condition requires contacting a specialist. Reviews about Bicyclol are mostly positive.
Special recommendations
Against the background of treatment, it is important to regularly monitor liver indicators, as well as the course of the disease. If the patient has a history of concomitant gastrointestinal complications, such as gastritis, cholecystitis, pancreatitis, the use of Bicyclol may affect the activity of alkaline phosphatase, hydrochlorothiazide, and AST in the direction of amplification. For this reason, treatment of patients in this situation is carried out with caution and under strict medical supervision. Also, treatment will require additional control of a number of hepatobiliary system values.
There is no data on the effect of Bicyclol on psychomotor reactions, since no studies have been conducted in this area. For this reason, the drug is considered to be conditionally dangerous for the performance of work requiring increased concentration of attention, driving, etc.
Reviews of the effect of "Bicyclol" consider below.
The effect of bicyclol on the intrauterine development of the fetus and newborn was not studied, therefore, pregnancy and the lactation period are considered a contraindication for taking the drug.
The chemical compound of the drug can reduce the amount of fluid passing through the placenta to the fetus, which can adversely affect the development of bone structures of the unborn child. This compound can lead to the development of malignant tumors in the fetal liver and leukemia.
You should also pay attention to the characteristics of the drug associated with its administration by patients with impaired renal or hepatic function. With prolonged use of the drug, bilirubin may increase. If the patient has been diagnosed with pyelonephritis, acute cholecystitis, urolithiasis or cholelithiasis, as well as kidney failure, treatment with Bicyclol should be postponed until these pathologies are cured. Along with nephroprotectors at the terminal stage, it is allowed to take the drug no more than 75 mg per day.
Analogs
The list of drugs that can successfully replace Bicyclol is quite impressive. The most popular generics of the drug are the following medications:
- Antral.
- "Unilive."
- Glutarsol.
- Essliver.
- Esavit.
- Hepel.
- "Phospholip."
- "Carsil."
- "Darsil."
- Thiotriazolinum.
- Simepar.
- Ornithox.
- Galstena, etc.
Gepa-Merz
The drug "Hepa-Merz" is most often prescribed as a substitute for "Bicyclol." It has a detoxifying effect, due to which it becomes possible to reduce the level of ammonia in the body, including during pathological processes in the liver. "Hepa-Merz" is prescribed for liver diseases occurring in acute or chronic form, accompanied by hyperammonemia, as well as in latent or severe form of hepatic encephalopathy, steatohepatitis and steatosis of various origins. In addition, the drug is used for parenteral nutrition in protein deficiency.
The price, reviews and analogues of Bicyclol are presented in the article.
Another popular drug from the group of hepatoprotectors is Essential. It is especially effective if metabolic hypoactivity of the liver is observed. The drug provides the liver with well-digestible high-energy phospholipids. Thus, it is possible to establish the enzymatic activity of the liver cells and normalize the activity of the liver as a whole. "Essential" stabilizes the physico-chemical properties of bile, improves the regenerative qualities of the liver, and also establishes metabolic processes in the body.
The choice of analogue should be agreed with the attending physician, since each drug has its own list of contraindications.
Reviews about Bicyclol
Patients and doctors in general respond positively to the effect of the drug. Improvement is observed after one week of taking the pills. Experts say that while taking the drug, liver transaminase and AST activity indicators return to normal, and the load on healthy hepatocytes decreases.
The main advantages of the drug "Bicyclol", according to doctors, include the following:
- The actual absence of adverse reactions inherent in the intake of most other hepatoprotectors.
- Affordable cost.
- Convenient form of use.
Some patients are distrustful of the medication. They claim in reviews of Bicyclol that, contrary to popular belief, the drug is not able to completely get rid of hepatitis, it only temporarily improves liver function. For many, after discontinuation of the drug, indicators such as bilirubin and AST returned to their original values, which were before the use of Bicyclol. Among people who used the drug, it is widely believed that in order to achieve a stable effect, it is necessary to take it throughout life. There are also opinions that the drug does not have any therapeutic effect.
The cost of "Bicyclol"
The approximate price of the drug (18 tablets) is 1850-2300 rubles. It depends on the region and the pharmacy network.
We reviewed the preparation "Bicyclol" instructions for use, price, reviews and analogues.