It is known that elevated cholesterol is often the main cause of pathological conditions, which very often lead to death. That is why, when a patient chooses to find cholesterol levels in excess of the permissible norm, a specialist in the field of medicine should prescribe drugs that affect its decrease. Next, we consider how to treat high cholesterol with tablets, the basic principles of the effects of these drugs, as well as a list of the best of them.
Basic principles of drug selection
To date, pharmaceutical companies offer a wide selection of drugs that positively affect the reduction of cholesterol in human blood. It should be noted that among them are both expensive and cheap drugs and, by the way, their price does not always indicate the level of quality - when choosing tablets for high cholesterol, you should rely solely on the individual characteristics and tendencies of the human body, as well as completely Follow the recommendations of your doctor.
When selecting a drug for a particular patient, the specialist determines the degree of organ damage with increased cholesterol.
After the patient is prescribed a specific drug, the specialist should monitor his health. In the event that positive dynamics are not observed, the medicine is replaced by another.
Types of medicines
Modern pharmaceutical companies offer two types of tablets for high blood cholesterol: fibrates and statins. Let us further consider the specific effects of each of these groups.
As for statins, they are HMG-CoA reductase inhibitors. Among this group there are the cheapest medications designed to lower cholesterol. As for the significant disadvantages of this group, the main one is that statins have a large number of side effects. In this regard, the patient taking the drugs of this group should be constantly monitored by the attending doctor throughout the entire period of treatment.
As for the main active substances included in the preparations of this group, then they include simvastatin, fluvastatin, atorvastatin, rosuvastatin and pitavastatin.
Speaking about drugs from the group of fibrates, it should be noted that they are derivatives of fibroic acid. Among the drugs of this group can also be found inexpensive. The main feature of these medications is that they are used, as a rule, in combination with statins, their appointment as the main drugs is, rather, an exception.
As for the mechanism of action of tablets from the group of fibrates, it consists in the fact that under the influence of the drug, lipoproteinplase begins to activate, as a result of which the cholesterol particles begin to split. As a result of this, lipid metabolism is accelerated, and the level of beneficial cholesterol also rises sharply. Practice shows that the effect of such drugs significantly reduces the risk of atherosclerotic plaque formation, as well as the occurrence and development of cardiac pathologies.
The main advantage of fibrates is that the drugs of this group are well tolerated by patients and rarely cause side effects.
The basis of drugs from the group of fibrates are substances such as fenofibrate, bezafibrat, ciprofibrate and choline fenofibrate.
Next, we consider the list of names of tablets for high cholesterol in the blood, which are most often recommended by specialists in the field of medicine for their patients, as well as the main features of their effect on the human body.
Atorvasatin
Among the best medicines, the action of which is aimed at lowering cholesterol in human blood, includes Atorvasatin, a drug that is currently produced by many manufacturers in different countries of the world.
The basis of this drug is atorvastatin calcium, which is usually referred to the group of lipid-lowering drugs of synthetic origin. In addition, this component is also commonly classified as a selective type of HMG-CoA reductase inhibitor.
The main effect of the drug in question is a significant decrease in the levels of LDL and VLDL (lipoproteins), which have a low and very low density, as well as triglycerides. Moreover, under the influence of Atorvasatin active substances, the synthesis of cholesterol in the human liver is actively inhibited, due to which the level of apolipoprotein B is neutralized. The drug also increases the level of high density lipoproteins, which positively affects the general condition of blood and blood vessels.
"Atorvasatin" refers to a group of statins. In the reviews of specialists in the field of medicine, it is noted that these pills for high cholesterol can reduce a negative indicator by 30-46%, which is an excellent result.
Consumers are pleased with the low cost of tablets - the price per package is about 130-140 rubles.
Atoris
Atoris are good pills for high cholesterol, which are produced by the pharmaceutical companies of the Krka group, as well as their branches. The main active component of this drug is atorvastanin, whose main action is aimed at significantly reducing the risk of angina pectoris (by 26%) and coronary heart disease (by 16%). Moreover, under the influence of atorvastanin, the process of blocking macrophages occurs and the possibility of rupture of atherosclerotic plaques is prevented.
Atoris is a drug that belongs to the category of statins. It is available in the form of small white convex tablets of a round or oblong shape, in various dosages of the main substance: 30, 60 and 80 g.
This drug is strictly contraindicated for use by all persons under the age of 18 during pregnancy and lactation, as well as in the presence of kidney and liver diseases.
The cost of this medication is about 310-390 rubles, depending on the region of the country.
Novostat
How to treat high blood cholesterol? Tablets "Novostat", according to many experts in the field of medicine, are an excellent tool for this. Under their influence, a rather quick and effective decrease in cholesterol level occurs, as a result of which the risk of complications in the work of all organs of the cardiovascular system is also neutralized.
The basis of "Novostat" is atorvastatin. As a result of its effect, there is a decrease not only in cholesterol, but also in triglycerides. A positive effect from the use of this drug is also that the medication provides an increase in the number of high density lipoproteins (beneficial cholesterol). "Novostat" is a medication that has an antiproliferative and antioxidant effect.
In addition to atorvastatin, Novostat includes components such as povidone K-17, sodium lauryl sulfate, lactose monohydrate, microcrystalline cellulose, magnesium stearate and sodium carboxymethyl starch. The drug in question has a lot of side effects that can occur as a result of improper use of the drug. These include symptoms such as asthenia, heartburn, vomiting, nausea, runny nose, anemia, tachycardia, tinnitus and weakness, as well as pronounced sleep problems.
In Russian pharmacies, the price of Novostat may vary depending on the volume of packaging: from 300 to 600 rubles.
Torvakard
What pills for high blood cholesterol help best? Among these, experts in the field of medicine often include Torvacard, a medication produced by the Czech pharmaceutical company Zentiva.
A significant disadvantage of the drug in question is that after its use, there is often a manifestation of side effects, expressed by hyperglycemia, constipation, belching, dyspepsia, liver dysfunction, allergies, and headaches. It should be noted that all these effects often accompany the administration of drugs from the group of statins, which includes Torvakard.
Torvacard is a competitive inhibitor of the HMG-CoA reductase of the selective group, the main action of the active components of which is aimed at regulating the rate of conversion of 3-hydroxy-3-methylglutaryl-coenzyme A to one of the sterol precursors - mevalonate. Atorvastanin, as the main active ingredient of the drug, reduces the level of cholesterol concentration in human blood, which occurs as a result of inhibition of HMG-CoA reductase, as well as the effective synthesis of cholesterol in the liver.
The active components of this drug are absorbed quickly enough, and excess is excreted along with bile, only after extrahepatic and hepatic biotransformation.
The average cost of packing Torvakard is about 450 rubles.
"Rosuvastanin"
Among the best pills for high cholesterol is a medication from the group of statins - "Rosuvastanin." This drug is sold in almost all Russian pharmacies, it is presented in the form of rounded pink small pills.
The agent under consideration belongs to the group of inhibitors of HMG-CoA reductase of a selective type, a competitive subtype.
At the very beginning of taking this drug, the patient should be established daily monitoring by specialists. In the reviews of doctors, it is often noted that the first positive effect of taking "Rosuvastanin", as a rule, is observed already a week after the start of a stable and correct administration of the drug. After a couple of weeks, the patient's condition is stabilized by 90%, and the maximum treatment effect is achieved in the third week. It should be noted that the positive effect of the drug is subsequently maintained on an ongoing basis.
The composition of the drug "Rosuvastanin", in addition to the main active substance of the same name, also includes other auxiliary components: magnesium stearate, titanium dioxide, glycerol triacetate, red iron oxide, calcium phosphate and glucose monohydrate.
Specialists in the field of medicine note that taking Rosuvastanin should not be taken immediately after detecting a problem of high cholesterol in the blood, but only if other supportive measures to combat it (sports, diets, the use of weight adjustment techniques, etc.) .) did not bring the desired result. This is due to the fact that the use of this drug, as well as other drugs assigned to the group of statins, has a lot of side effects that can manifest themselves in a variety of body systems:
- cardiovascular
- CNS
- digestive
- cardiovascular
- respiratory
- musculoskeletal.
Rosuvastanin has a fairly reasonable pricing policy - the average cost of a pack of drug is about 280 rubles.
The tool in question has a number of analogues, which include: Roxera, Mertenil, Rosart, Akorta, Rosistark, Tevastor, Akorta. Despite the large list of alternative medications that have a similar effect on the human body, most medical experts still recommend treating it with Rosuvastanin, since this remedy has long been proven to be the best and has proven its undeniable effectiveness. Practice shows that the effect of using the medication becomes noticeable only after a couple of weeks of administration, since the active substances of such tablets act cumulatively.
Roxer
Roxera is an effective statin pill for high cholesterol, which is produced by pharmaceutical companies of the Krka group. It should be noted that this drug is not suitable for those individuals who suffer from individual intolerance to lactose and milk sugar, since in its composition, along with other active components, this element is present.
The main effect of this drug is aimed at the conversion of methylglutaryl coenzyme to mevalonic acid. Once in the body, this remedy for high cholesterol (in tablets) has a special effect on the liver - the organ in which the bulk of the processes of cholesterol synthesis and catabolism of lipoproteins having a low density take place.
The basis of the composition of this drug is the substance rosuvastanin, which may be contained in various dosages: from 5 to 20 mg. Depending on the dosage of the main ingredient in the composition of the drug, the price of tablets can vary from 300 to 2500 rubles. In modern Russian pharmacies, you can also find cheaper analogues of this drug: Rosistark (from 91 rubles), Rosulip (from 82 rubles), Suvardio (from 41 rubles), Rustor (from 41 rubles) .), as well as “Akorta” (from 62 rubles), however, if you want to use an analogue, you should consult a doctor on this issue, since some of the components of such drugs may differ and be incompatible with some features of the body's perception of individual elements.
Doctors say that Roxer is one of the best pills for women with high cholesterol. If the specialist correctly selects this drug, the positive effect of its administration is observed after 5-8 days, and the most persistent effect can be observed after 2-3 weeks.
"Crestor"
What pills to take with high cholesterol? Practice shows that when the problem in question is discovered, Krestor tablets, which can be easily found in Russian pharmacies, help to combat it. This drug product is produced by the British pharmaceutical company Astra Zeneka, as well as its branches established in different countries of the world. It should be noted that this drug has long gained great popularity among the representatives of the Russian population, since it is it that shows great effectiveness in the fight against the problem under consideration.
"Krestor" - a quality pill for the treatment of high cholesterol, classified as statins. The tool belongs to the group of lipid-lowering and is quite widely used to combat excess cholesterol.
The composition of the drug in question is based on an effective active substance - rosuvastatin. In addition to it, the structure of the drug contains elements such as calcium phosphate, lactose monohydrate, MCC, magnesium stearate and crospovidone. The purpose of this drug is possible for both adults and children over 10 years of age.
The drug in question has a rather high price policy, however, according to most medical experts and consumers, it is fully justified by the effectiveness of the pills - the price for the packaging of Krestor is from 1050 to 1470 rubles, depending on the dosage of the main component. If desired, the patient, after agreement with the doctor, can carry out treatment by taking analogues of the drug in question, which include: Rosucard, Rosulip, Klivas 20 and Klivas 10, Romestin 20, Rosusta, but, according to doctors, the most effective among them is Rosart.
Gemfibrozil
What pills to drink for high cholesterol? An excellent option for a drug from the group of lipid-lowering drugs is considered to be "Gemfibrozil" - a product created on the basis of gemfibrozil.
The main pharmacological action of the drug in question is to actively reduce the number of lipoproteins having low density, as well as triglycerides. Moreover, this tool inhibits peripheral lipolysis, and also has a positive effect on the activation of the process of removing free fatty acids from the liver. Against the background of these processes, there is a faster turnover of cholesterol in the body and its subsequent elimination.
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With increased cholesterol in women, Exlip 200 tablets are contraindicated during lactation and pregnancy. Also, this tool is not recommended for children. Moreover, it is forbidden to prescribe in case of observation in a patient of pronounced problems with the functioning of the liver and kidneys.
Exlip 200 is a drug manufactured in Turkey; its cost in the Russian pharmaceutical market is about 800-1000 rubles.
Despite the fact that the modern pharmaceutical market offers a lot of options for what to drink with high cholesterol, tablets for treatment should be selected exclusively in accordance with the recommendations of the attending physician and only after passing the tests.