According to the instructions, "Amoxicar plus" is a drug that is included in the group of penicillin-based drugs. The drug has an antibacterial effect. It is active against streptococci, staphylococci, as well as pathogens of gonorrhea, salmonellosis, meningitis and purulent sepsis. In addition, Amoxicar is active against shigella, E. coli and Klebsiella.
Structure
Amoxicar Plus is produced in the form of capsules of 250 and 500 mg, as well as granules for the preparation of a suspension of 125 and 250 mg of the active ingredient per 5 ml.
Both versions of the drug are intended for oral administration. Amoxicillin acts as the active substance in the drug. Amoxicar Plus for children and adults is prescribed for the treatment of many infectious diseases of bacterial origin.
Indications for appointment
Indications for use of the drug are:
- Pneumonia.
- Bronchitis.
- Pharyngitis.
- Sinusitis.
- Otitis media in acute form.
- Pyelitis.
- Tonsillitis.
- Gonorrhea.
- Pyelonephritis.
- Cystitis.
- Urethritis.
In addition, Amoxicar Plus is used as part of complex therapy for the following pathologies:
- Cervicitis
- Endometritis.
- Cholecystitis.
- Erysipelas.
- Cholangitis.
- Lyme disease.
- Dermatosis is a secondary infected type.
- Meningitis.
- Sepsis.
- Salmonellosis.
- Listeriosis.
- Peritonitis.
- Endocarditis.
A prerequisite for taking the drug is to receive an appointment from a doctor, since its independent use can cause the development of unwanted reactions and complications.
Instructions for the use of a medication
Amoxicar Plus is intended for oral administration during meals, before or after it (there is no difference). The dosage for adults and children who are over ten years old, as well as for those whose weight is more than forty kilograms, is 500 mg in the morning and evening. Another dosage option is 250 mg three times a day.
When it comes to infectious diseases that occur in severe form, as well as damage to the upper respiratory tract, Amoksikar is prescribed 850 mg in the morning and evening or 500 mg three times a day.
The dosage of Amoxicar Plus 250 suspension for children over 5 years old is as follows: they should be given 1 scoop three times a day. The interval between doses must be maintained for 8 hours.
For the treatment of children under five years of age, a suspension of 125 mg of amoxicillin is used. Dosage:
- Suspension "Amoksikar plus" for children under two years of age is given at 20 mg per kilogram of body weight of the child. The daily dosage is divided into three times.
- From the age of three years to five years, the dosage of the drug increases to 125 mg, which are taken three times a day. When treating with a suspension with a concentration of 125 mg of the basic substance, an eight-hour interval between doses must also be maintained.
For children older than five, but younger than 12 years old, they try not to use a suspension with a concentration of the main substance of 125 mg, since it does not have the desired effect. The above dosage of Amoxicar Plus suspension by 250 children of this age is usually well tolerated.
The maximum daily dose of the drug for adults and children who are over 12 years old is six grams. Children under 12 years of age should not take more than 45 mg per kilogram of body weight per day.
The duration of treatment with Amoxicar most often does not exceed a two-week period. Otitis media is treated for approximately ten days. If the patient has kidney failure in a chronic form, it may be necessary to adjust the dosages prescribed by the instructions.
Amoxicar Plus hemodialysis patients are prescribed 250 or 500 mg.
One dose is given before the procedure, and the second after it.
Contraindications to the use of the drug
Suspension "Amoksikar plus" has some limitations of admission. Not all infectious diseases require the use of antibiotics. In addition, not all bacteria are susceptible to amoxicillin.
A drug should not be prescribed for the treatment of jaundice, mononucleosis of infectious origin, phenylketonuria, as well as acute and renal and / or liver failure. It is also forbidden to take "Amoksikar" with hypersensitivity to amoxicillin. In this case, you need to choose a drug based on another active component.
Adverse reactions from the use of this medication
If the drug is taken incorrectly and the dosages prescribed by the instructions are exceeded, the following undesirable reactions may develop:
- Skin rash.
- Fever.
- Arthralgia.
- Rhinitis.
- Angioneurotic edema.
- Exudative erythema multiforme.
- Exfoliative dermatitis.
- Glossitis.
- Nausea and vomiting.
- Stomatitis.
- Anaphylactic shock.
- Diarrhea.
- Emotional excitement.
- Depressive state.
- Ataxia.
- Anxiety.
- Sleep disturbance.
- Epileptic seizures.
- Headache.
- Dizziness.
- Increased activity of liver transaminases.
In addition, while taking the drug, anemia, tachycardia, leukopenia, vaginal candidiasis, and thrombocytopenic type purpura can progress. To avoid the above complications, the prescribed dosages and the duration of taking Amoxicar should be observed.
Special recommendations for the use of the drug
As indicated by the instructions for use with Amoxicar Plus, when taking an excessive amount of the drug significantly exceeding the prescribed dosages, intoxication of the whole organism may begin. The main signs of poisoning can be nausea and vomiting, dyspeptic disorders, disturbed water-electrolyte balance. If symptoms of an overdose are identified, you should stop taking the drug and wash the stomach with the subsequent intake of enterosorbents.
Careful use of this drug
With special care and under strict medical supervision, Amoxicar is prescribed during pregnancy and breastfeeding.
In addition, caution should be exercised when administering the drug to patients with kidney or liver failure, in severe stomach or intestinal diseases, hives, and hay fever.
Amoxicar should be taken for several days after the disappearance of all clinical manifestations of the pathology.
Amoxicar Plus or Amoxiclav - what to choose?
If we talk about substitutes for Amoxicar with a similar composition, the most popular is Amoxiclav. Both drugs contain an identical active substance from the category of penicillins. The difference between one and the other is the presence of another active ingredient in the composition of Amoxiclav - potassium clavulanate, which significantly increases the direction of action of the drug.
Thus, the main difference in terms of activity against bacteria between the two drugs is:
- "Amoksikar" is active in gram-positive microorganisms, but actually has no effect on gram-negative ones.
- Amoxiclav and Amoxicar Plus have a detrimental effect on both gram-positive and gram-negative bacteria. It can be used even in cases where the pathogen has not been identified.
Sodium clavulanate not only enhances the effectiveness of Amoxiclav, but also affects microorganisms. It can be concluded that Amoxiclav is a new generation drug that is more effective than Amoxiclav.
The combination of a drug with other drugs
Amoxicar cannot be taken simultaneously with aminoglycosides. Antacids, laxatives and glucosamine slow the rate of absorption of amoxicillin. Ascorbic acid enhances its effect.
In combination of the drug in question with antibiotics of the bactericidal type, a synergistic effect occurs. Bacteriostatic drugs have an antagonistic effect when taken with amoxicillin.
Amoksikar enhances the effectiveness of indirect anticoagulants, but reduces the effect of oral contraceptives. The toxicity of methotrexate is enhanced by the combination with amoxicillin.
The concentration of the drug increases while taking diuretics, phenylbutazone, NSAIDs, allopurinol, etc. The likelihood of an allergic reaction in the form of a rash increases with the combination of amoxicillin and allopurinol.
Reviews on this drug
Amoxicillin has been used for over 40 years. Even now, it is the best-selling antibiotic. Semisynthetic penicillins, which include amoxicillin, are much more effective against gram-negative bacteria, unlike their natural precursors. Amoxicillin is taken only 2-3 times a day.
According to reviews, Amoksikar is often prescribed for children to treat otitis media. This is due to the fact that the drug is effective against pneumococci and hemophilic bacillus, resistant to penicillins. Parents respond positively to the effect of the drug.
Amoxicar helps middle-aged patients cope with mild pneumonia, which is treated outside the hospital. When treating both adults and children, one should not forget that Amoxicar is an antibiotic. You cannot assign it yourself.
The reviews and shortcomings of the drug are noted. One of them is difficulty in diluting the suspension, as well as its unpleasant taste. Some children refuse to take the drug for this reason. Another problem with this drug, patients call it contraindications and side effects. However, this is a disadvantage of all antibiotics.
Another disadvantage of the drug is that it can not be found in every pharmacy. drug in pharmacies. Therefore, you have to resort to similar drugs, such as Flemoxin Solutab, Ospamox, Amoxin. However, before taking the analogue, you must consult your doctor.
We examined the medicine "Amoksikar plus" instructions for children and adults.