Fluconazole is a wonderful antifungal drug. It can be presented in the form of syrup, capsules, powder for the preparation of a suspension, solution for injection.
"Fluconazole", instructions for use describe its action in detail, inhibits, i.e. slows down the vital activity of fungi, which depend on cytochrome P450, does not allow fungal cells to convert lanosterol to ergosterol. The medicine disrupts the replication and growth of the cell membrane of fungi. However, acting on them, "Fluconazole", the instructions for use soothe, do not inhibit the oxidation processes associated with cytochrome in the human body. Such properties of the drug allow you to actively fight against fungal diseases caused by a variety of pathogens.
Who is fluconazole indicated for? The use of the drug has a wide range of indications:
- Treatment of systemic diseases provoked by cryptococci: meningitis, skin, pulmonary infections. It is interesting that the drug actively copes with fungi both in people with normal immunity and in patients with AIDS and other immune problems.
- Prevention of infection with cryptococci during organ transplantation in patients with AIDS.
- Candidaemia treatment.
- Treatment and prevention of generalized disseminated candidiasis that affects the eyes, abdominal organs, urinary organs, endocardium.
- Prevention and treatment of candidiasis of the oral cavity or pharynx.
- Treatment of bronchial or pulmonary candidiasis.
- Prevention of mucocutaneous atrophic or oral candidiasis caused by wearing removable dentures.
- Genital candidiasis, ban.
- Prevention of fungal infections in patients undergoing radiation, chemotherapy or radiotherapy.
- Mycoses: groin, body, feet, skin, pityriasis versicolor, onychomycosis
- Treatment of endemic mycoses: histoplasmosis, sporotrichosis, coccidioidosis,
"Fluconazole", the composition of which can cause allergic reactions in some people, is not shown to everyone. People suffering from alcoholism, liver or kidney failure, pregnant, lactating, elderly people are not recommended to take it. Do not use the drug to treat children.
"Fluconazole", instructions for use contain this information, can cause some side effects. Although they were most often observed when exceeding the recommended dosage or unreasonably long therapy, patients undergoing treatment and prescribing medications need to consider this danger.
A medicine may cause:
- impaired stool, appetite, increased flatulence, toothache, epigastric pain;
- impaired liver function, hyperbilirubinemia, jaundice;
- fatigue, drowsiness, headache, rarely - cramps;
- exudative erythema, Lyell's syndrome, anaphylactic shock;
- allopecia (baldness), hypertriglyceridemia, impaired renal activity, hypokalemia
In addition, exceeding the prescribed doses of the drug "Fluconazole", instructions for use warns about this, can cause an overdose. In this case, the appearance of hallucinations, confusion, the development of paranoid behavior. In this case, immediate medical attention is required: gastric lavage, hemodialysis, forced diuresis.
Treatment with "Fluconazole" is recommended to continue until a stable remission appears. Early interruption of treatment can lead to relapse of the disease. The dosage and duration of the course in each case is determined by the doctor.
The medicine has analogues: drugs, the active substance of which is fluconazole. These include: "Flucostat", "Diflucan", "Mikomaks", "Mikosist", "Procanazole", "Fluol", some other drugs.