A few decades ago, high blood pressure was considered a disease of the elderly. But today hypertension can be found even in young people. There are many reasons for this, but the main ones are two: a sedentary lifestyle and an unbalanced diet.
Capillaries do not have a certain thickness. Therefore, they can narrow and expand depending on the intensity of blood flow, as well as blood volume.
The following factors may provoke a slight increase in pressure:
- heavy eating;
- weight lifting;
- intense physical activity, running;
- smoking;
- caffeinated drinks;
- use of drugs;
- nervous strain.
If a person is healthy, after ten to fifteen minutes after the abolition of these factors, blood pressure should return to normal. If there are problems with the vessels - due to their low elasticity or clogging with cholesterol plaques, it becomes difficult for the vessel to restore normal blood flow. With increased pressure, patients need to constantly measure it. In addition, the doctor may prescribe mild sedative medications if the increase is due to stress and anxiety. In another case, the doctor may recommend an antihypertensive medication, for example, Enalapril.
The danger of high blood pressure
During vascular stenosis, pressure on the walls increases, which leads to rupture of fragile membranes and bleeding. If this happens in the brain, then partial or complete paralysis can occur, as well as serious impairment of consciousness and even death.
Reducing the volume of pumped blood leads to oxygen starvation and low nutrition of certain tissues and organs, as a result of which their functioning is disrupted.
As a rule, people with high blood pressure are very thick, as well as prone to clot formation. With healthy capillaries, a blood clot can travel with a blood stream without causing serious health problems. But, penetrating into the narrowed lumen, it can block the blood flow, which becomes the cause of tissue death.
Description of the medication
"Enalapril" refers to antihypertensive drugs of the group of angiotensin converting enzyme inhibitors. The drug is used to eliminate pathological conditions that are accompanied by an increase in blood pressure.
"Enalapril" is made in tablet form for oral use. The main active substance of the drug is the component of the same name, its concentration in 1 tablet is 5, 10 and 20 milligrams. In addition, the composition of the drug includes additional elements, which include:
- magnesium salt of stearic acid;
- lactose monohydrate;
- magnesium salt of carbonic acid;
- polyvinylpyrrolidone;
- gelatin.
Tablets are packaged in a blister pack of ten pieces.
When appointed
According to the instructions and reviews for the drug "Enalapril", indications for use are:
- Hypertension (a pathological process of the cardiovascular apparatus that occurs as a result of a violation of the higher centers of vascular regulation, as well as neurohumoral and renal mechanisms, leading to an increase in blood pressure, as well as functional and organic changes in the heart, central nervous system and kidneys).
- Raynaud's disease (vasospastic disease, which is an angiotrophoneurosis with lesions of small terminal capillaries and arterioles).
- Heart failure.
- Symptomatic arterial hypertension (a hypertensive disease that occurs as a result of damage to organs that regulate blood pressure).
- Diabetic nephropathy (kidney damage that is characteristic of people with diabetes).
- Scleroderma (a disease of connective tissue, the main manifestation of which is a violation of the microcirculation of blood and compaction of organs and tissues).
- Secondary hyperaldosteronism (a disease that is characterized by increased hormone production, but is not associated with a pathological process in the endocrine system).
- Angina pectoris (a pathological process that occurs as a result of oxygen deficiency in the heart muscle).
- Myocardial infarction (a source of ischemic necrosis of the heart muscle, which occurs as a result of acute disturbance of coronary circulation).
After use, Enalapril is almost completely absorbed into the bloodstream.
At what pressure is the drug used
"Enalapril" is prescribed to combat high blood pressure in patients with renovascular arterial hypertension. In addition, the drug is used for the complex treatment of chronic heart diseases.
"Enalapril": contraindications and side effects
There are several conditions in which it is forbidden to take the drug. These include:
- Angioneurotic edema (acute condition, which is characterized by the rapid onset of edema of the mucous membrane, as well as subcutaneous tissue and skin).
- Bilateral stenosis of the renal arteries or stenosis of the artery of a single kidney (narrowing of the lumen of the capillaries, which is provoked by congenital causes, as well as atherosclerosis and inflammatory changes).
Are there any other contraindications to Enalapril? The drug is prohibited for use with:
- Hyperkalemia (a pathological disease that provokes an abnormally high content of potassium in the blood).
- Established individual intolerance.
- A condition after a kidney transplant.
- Alcoholism.
- Pregnancy, regardless of the term.
To prevent the occurrence of side effects from Enalapril, contraindications for use must be completely eliminated.
When using the drug, the development of negative reactions from various organs and systems is likely:
- Migraine (headache, which is characterized by attacks of medium and high intensity).
- Vertigo (the disease, most commonly known as dizziness, it develops with damage to the hearing organs and brain).
- Fatigue.
- Sleep disorder.
- Imbalance.
- Noise in ears.
- Fainting.
- Orthostatic hypotension (a condition that is characterized by a violation of the body's ability to maintain a normal level of blood pressure in an upright position).
- The appearance of palpitations.
- Pain in the heart.
- Nausea.
- Vomiting.
- Dry mouth.
- Diarrhea.
- Pain in the abdomen.
- Increased bilirubin concentration.
- Hepatitis (inflammatory damage to the liver, in most cases of viral etiology).
- Pancreatitis (a disease characterized by acute or chronic inflammatory lesions of the pancreas).
- Proteinuria (a condition in which there is a high protein content in the urine).
- Periodic dry cough.
- Neutropenia (a pathology in which the number of neutrophils is greatly reduced in the human body).
- Alopecia (pathological hair loss, which leads to their disappearance in certain areas of the head or body)
- Rashes on the skin.
- Itching
- Urticaria (skin lesion, allergic origin, which is characterized by a sharp appearance of itchy blisters).
- Quincke's angioedema (a reaction to the influence of various biological and chemical factors, which in most situations is allergic in origin).
The occurrence of unpleasant symptoms is considered the basis for the abolition of Enalapril tablets and contacting a doctor for advice.
Dosage and administration
The tablets are intended for oral use. They are taken whole without chewing and drinking with water. The initial pharmacological concentration of the active substance is 2.5 milligrams twice a day. Subject to the dosages and prescriptions of the doctor, as well as taking into account all contraindications, side effects from Enalapril practically do not occur.
The average therapeutic concentration of the active ingredient varies from 10 to 20 mg per day, the reception is divided into 2 uses. The course of therapy is usually long, sometimes life-long.
Dose adjustment and determination of the duration of treatment is decided by the doctor individually. What are the contraindications and side effects of Enalapril?
Why the drug and alcohol are not compatible
This medication is prescribed by a specialist who determines the method of therapy and dosage. Taking alcohol with medicine, a person enhances the effect. This can lead to a weakening of the body.
According to the instructions, the use of alcohol is a contraindication to the use of Enalapril. This is due to the fact that the medication lowers blood pressure, and strong drinks only increase the effect of the drug.
Some people who took Enalapril concomitantly with alcohol claim the opposite, explaining that blood pressure decreases faster, and this condition remains for a long time. In reality, when using the drug in conjunction with alcohol, a person can significantly lower blood pressure, which leads to serious health problems. In addition, Enalapril enhances intoxication, and this adversely affects the functioning of internal organs.
According to the reviews and instructions for tablets "Enalapril", a contraindication to the use of the drug is withdrawal symptoms. In this situation, constant abuse of strong drinks expands blood vessels, and lack of alcohol leads to increased pressure.
The drug in this situation will not help, but only worsen the condition and can lead to diseases of the heart and liver.
Effects
The following manifestations are considered to be the result of alcohol intake, even with a low ethanol content, with the Enalapril medication:
- frequent breathing
- increased intoxication;
- hoarseness;
- noise in ears;
- the appearance of a veil before the eyes;
- impaired coordination of movements;
- nausea;
- gagging;
- cramps
- lack of appetite;
- depressive disorders;
- diarrhea;
- rare urination;
- slowing the blood microcirculation in the brain, which leads to stroke and heart attack;
- overexcitation of the central nervous system.
If such unpleasant symptoms occur after the simultaneous use of alcohol and medication, you should immediately consult a doctor. In case of deterioration of health, it is necessary to ensure absolute peace for the patient and call a doctor. As previously stated, alcohol intake is a contraindication to Enalapril Hexal.
Drinking the drug with alcohol can provoke postural hypotension. This violation occurs due to poor blood flow in the heart, while significantly reducing pressure. The brain does not receive the necessary oxygen concentration, which leads to a fainting state and, as a result, to fainting.
Some people take the drug after drinking alcohol to eliminate the hangover syndrome. This is categorically contraindicated, since the effects of Enalapril can turn in the other direction and adversely affect human health.
There are such patients who manage to drink drugs with alcohol. As for Enalapril, this is a gross mistake. Firstly, blood pressure can significantly decrease, and secondly, a heart attack can occur. Side effects will not keep you waiting, even to the point of death.
“Enalapril” contains components that contribute to the expansion of capillaries and a decrease in blood pressure. Alcoholic beverages themselves have a negative effect on health, and taking it simultaneously with this drug leads to the following pathological processes:
- Red blood cells accumulate and form dense growths. These formations settle on the walls of the capillaries, contributing to the development of blood clots.
- Impaired functioning of the heart. Myocardial elasticity worsens, the necessary substances arrive in a small volume. This leads to a stroke or heart attack.
- Deterioration in liver function. Each medication adversely affects this organ, but in combination with alcohol - it has a toxic effect. Liver cells are destroyed, fat deposits occur in their places. This disrupts blood filtration, which impairs the release of toxins.
How to take Enalapril after alcohol
If it happened that the patient drank alcohol, but there is a need to use the drug, proceed as follows:
- For three hours you need to consume a lot of water. This will help to quickly remove ethanol from the body.
- If a person took Enalapril with alcohol for the first time, the likelihood of adverse reactions is small.
- During therapy with the drug for a longer course, alcoholic beverages are prohibited from three to thirty days. The duration of treatment is determined by the doctor.
- After using the drug, it is necessary to withstand at least one and a half days, after which you can drink alcohol. Substances of the drug are excreted from the body in different ways. The representatives of the beautiful half for thirty-two hours, for men - no more than a day.
- If a celebration is planned, it is best to replace Enalapril with other antihypertensive drugs that have an instant effect. These medicines are better excreted from the body and do not have serious limitations, as well as side effects.
The use of Enalapril along with alcohol will entail not only the appearance of negative effects, but sometimes even death.
Recommendations
Before the "Enalapril" therapy, the specialist warns the patient about the presence of certain features of the use of the medicine:
- With prolonged use of the drug, regular medical monitoring of the blood is required.
- With extreme caution, Enalapril is prescribed to patients with diabetes mellitus, as well as autoimmune pathology, severe aortic stenosis, and hypertrophic cardiomyopathy.
- When performing surgery during the use of tablets, it may be necessary to adjust the level of blood pressure, since arterial hypotension may occur.
- Medication is prohibited for lactation and pregnancy.
- The medicine can come into contact with the means of other pharmacological groups, therefore, their use must be warned by a specialist.
- When taking the medicine, it is impossible to engage in activities that require increased attention.
In pharmacies, "Enalapril" is dispensed strictly according to a doctor's prescription.
Generics
The composition and pharmacological actions of the analogues are:
- Noliprel.
- Captopril.
- "Indapamide".
- "Losartan."
- "Lozap".
Storage
The shelf life of the tablets is 26 months. The medication should be stored in a dark, dry place at a temperature of fifteen to twenty-five degrees of heat.
The average price of Enalapril varies from 70 to 100 rubles.
Reviews
Before use, it is necessary to familiarize yourself with the indications and contraindications of Enalapril. The drug lowers blood pressure, but also has a number of limitations and adverse reactions, such as coughing. Doctors' reviews boil down to the fact that this is an effective, high-quality medication for blocking angiotensin-converting enzyme inhibitors.
According to reviews of patients who suffer from hypertension and take Enalapril, it is known that the drug is well tolerated and quickly reduces blood pressure. To maintain pressure at the required level, the medication should be taken constantly.
Some people forget to take the drug as prescribed by a specialist. Patients who suffer from diabetes, gave examples of a persistent increase in blood glucose levels with prolonged use of the drug. Most people have reported that Enalapril has been used for years without any side effects.