What can replace a drug like Magnesium Orotat? Analogs of this tool are listed below. Also, in the materials of the article, information is provided on the price of the mentioned medication, its properties and methods of use.
Form, description, composition
The preparation "Orotat Magnesium" is made in the form of white tablets, round and flat, as well as with a risk on one side and with chamfers on both sides.
What is part of this medicine? Magnesium orotate dihydrate is its main substance. In addition to this, the drug in question includes auxiliary ingredients in the form of sodium carmellose, colloidal silicon dioxide, microcrystalline cellulose, corn starch, povidone K30, sodium cyclamate, lactose monohydrate, talc and magnesium stearate.
On sale, this tool comes in blisters that are packaged in packs of cardboard.
Pharmacology
What is Magnesium Orotat? The instruction states that it is a magnesium preparation. As you know, the substance mentioned is the most important macrocell. It is essential for the human body to provide many energy processes that take part in the metabolism of fats, proteins, nucleic acids and carbohydrates.
It should also be noted that the trace element in question acts on neuromuscular excitation, thereby inhibiting neuromuscular transmission.
Magnesium is a natural physiological antagonist of an element such as calcium. It controls the normal functioning of myocardial cells, and also participates in the regulation of its contractile function.
In stressful situations, free ionized magnesium is excreted from the body in increased amounts, and its additional intake increases resistance to stress.
Magnesium deficiency
The drug "Magnesium Orotat" is intended to fill the deficiency of the most important trace element in the body. The lack of this substance contributes to the development of neuromuscular disorders (including seizures, increased sensory and motor excitability, paresthesia), cardiovascular diseases (including tachycardia, ventricular extrasystole, increased sensitivity to cardiac glycosides) and psychological changes (confusion, depression and hallucinations ) It should also be noted that during pregnancy, magnesium deficiency increases the risk of premature birth and toxicosis.
One cannot but say that salts of orotic acid take an active part in the metabolic process. They are also necessary for the manifestation of the action of magnesium and its fixation on ATP in cells.
Kinetics
After taking one dose of the drug "Magnesium Orotat" in the bloodstream, approximately 35-40% is absorbed. In this case, hypomagnesemia stimulates the absorption of magnesium ions, and the presence of salts of orotic acid significantly improve this process.
Magnesium is excreted through the kidneys. With a deficiency of this element, its excretion decreases, and with an excess, it increases.
Indications
Under what conditions can Magnesium Orotat be prescribed to a patient? According to experts, this tool should be taken with:
- atherosclerosis;
- heart rhythm disturbances, including ventricular arrhythmia in people with digital intoxication;
- arteritis;
- angina pectoris;
- acute myocardial infarction (for the prevention of arrhythmias);
- dyslipoproteinemia;
- alcoholism, a state of withdrawal syndrome;
- cachexia.
It should also be noted that Magnesium Orotat is very often recommended for those whose diet is low in protein and also low in calories.
The agent in question is actively used to make up for the lack of magnesium. Typically, such a deficiency is noted during breastfeeding and pregnancy, as well as with hyperthyroidism, hypercalcemia, hyperaldosteronism, reduced intake and absorption of the element, its increased excretion from the body, which is associated with impaired renal function, chronic diarrhea, etc.
Contraindications
Magnesium is contraindicated in patients with conditions such as:
- hypersensitivity;
- impaired kidney function;
- chronic and acute liver damage;
- urolithiasis, in which there is the appearance of magnesium-calcium and phosphate calculi;
- condition of AV and sinoatrial blockade.
The drug "Magnerot": instructions for use
The price of this tool will be indicated below.
According to the instructions, the drug in question is intended for oral administration. To significantly increase the effectiveness of this medication, it is recommended to take it 60 minutes before a meal. Tablets should be washed down with a large amount of liquid.
The duration of a conservative course of therapy should be determined by the attending physician in each individual case. Although the instructions indicate the general reception scheme.
At the very beginning of the treatment of magnesium deficiency, experts recommend using two tablets of the drug three times a day (for a week). After this, the dosage is reduced to one tablet at a time.
The maximum daily dose of this agent is 3000 mg (i.e. 6 tablets).
For people suffering from night cramps, this drug is usually prescribed in the amount of 2-3 tablets at bedtime (one-time).
Side effects
What adverse reactions can cause the drug "Orotat Magnesium"? Customer reviews claim that this tool is well tolerated by them. Although with self-administration of the drug in large doses, dyspeptic disorders of the gastrointestinal tract are possible, which are manifested by instability of the stool and diarrhea. Such unpleasant symptoms are stopped by reducing a single dose of the drug.
It should also be noted that clinical cases are known when, against the background of taking the magnesium preparation, skin allergies developed in patients in the form of characteristic exanthema, urticaria, papular and hyperemic rashes, and itching. The appearance of such signs requires immediate contact with your doctor to adjust the dose.
Interaction
Is it possible to combine the preparation “Magnerot” with other means? Instructions for use (the price of this medicine is not very high) claims that this medication should not be combined with iron salts, tetracyclines and sodium fluoride, since intestinal reabsorption of the latter is significantly reduced.
With the parallel use of magnesium with antipsychotics, sedatives or tranquilizers, their pharmacological effect is potentiated.
With the combination of Magnerot with antihypertensive and antiarrhythmic drugs, the severity of their therapeutic effect is enhanced (the development of bradycardic or hypotensive crises is possible).
Similar drugs and the price of the drug
You can replace the medication in question with such means as Panangin and Asparkam. Also in pharmacy chains, there are many other vitamin complexes containing magnesium.
As for the price, you can buy this drug for 160-180 rubles.
Reviews about the tool
Consumer reviews about this drug indicate its positive effect on the human body. Patients claim that after taking "Magnerot" their general condition became noticeably better.
Many experts are satisfied with this tool. They report that its use significantly reduces the risk of developing coronary heart disease. This fact is confirmed by numerous statistical data.
Also, pregnant women leave their comments on the drug "Orotat Magnesium". They claim that taking this remedy eliminated night cramps in them, and also reduced irritability and nervousness. However, doctors report that taking this medication when bearing a fetus should only be under the supervision of a qualified doctor.