Unfortunately, not all of us can boast an elegant figure. Some are overweight by nature, while others gain kilograms during life for various reasons (for example, as a result of taking hormonal drugs). And, of course, most people still seek to get rid of such a “burden” by all available methods. When diets and regular physical activity do not give a visible effect, many turn to pharmaceutical drugs for weight loss. One such remedy is the Listata Mini preparation. Reviews of doctors and consumers about this medication are quite mixed. Let's talk in more detail about this tool.
The composition of the medication
“Listata Mini” is a preparation containing the main active ingredient orlistat in its composition (60 mg in 1 tablet). Auxiliary components are: sodium lauryl sulfate, acacia gum, mannitol, crospovidone, polyvinyl acetate, povidone, copovidone, crospovidone, magnesium stearate.
A medication is produced in the form of oval tablets in light blue.
Drug action
Orlistat is a specific inhibitor of long-acting gastrointestinal lipases. When taking the drug inside, the active substance inhibits pancreatic and gastric lipases. As a result, the breakdown of dietary fats is impaired, and their absorption from the digestive tract is reduced. In this regard, the intake of calories in the body decreases, as a result, body weight decreases. The drug practically does not have a resorptive effect , since orlistat is almost not absorbed into the systemic circulation.
Weight loss will occur if 3 times a day at 60 mg take the drug "Listata Mini". The reviews of those who used this tool also indicate other positive aspects: under the influence of orlistat, the concentration of LDL cholesterol, total cholesterol decreases, and the waist circumference also decreases.
Already after 24-48 hours after taking the tablets in the stool, the fat content increases. 48-72 hours after drug withdrawal, the fat level returns to its original value.
Indications for use
The “Listata mini” medication is taken to reduce excess body weight (when the BMI - body mass index - exceeds 28).
Contraindications
Do you want to get rid of excess weight with the help of Listat Mini? Reviews of acquaintances or friends should not be the only weighty argument in favor of the mentioned medicine. Be sure to consult with an experienced specialist, since in some cases the use of the drug we are considering is contraindicated. So, this tool is not used for:
hypersensitivity to any component;
chronic malabsorption syndrome;
cholestasis;
simultaneous use of indirect anticoagulants (drug "Warfarin") and other oral anticoagulants;
simultaneous use of the medicine "Cyclosporin".
Also do not use this tool for children and adolescents under 18 years of age.
Use during pregnancy and breastfeeding
Reliable clinical data that would confirm the safety of the drug "Listata Mini" during pregnancy, today there is no. In this connection, this remedy should not be prescribed during the period of gestation of the baby.
It is also unknown whether the active substance penetrates into breast milk, therefore it is not recommended to use it for nursing mothers.
The embryotoxic and teratogenic effects of orlistat were not detected during experimental studies.
The drug "Listata Mini": instructions for use
This drug is taken orally before meals, immediately during or within an hour after eating. The recommended daily dose is 180 mg, the indicated amount is divided by 3 times.
When taking the Listata Mini medication, you should follow a moderately hypocaloric diet with a low fat content. You must also know that with an increase in the recommended dose, an increase in the therapeutic effect is not observed.
Overdose of the drug "Listata Mini"
Doctors' reviews indicate the following: with a single use of 800 mg of the drug and up to 400 mg of the drug three times a day for 15 days, significant adverse events (both in patients with obesity and with normal body weight) were not found.
When using 240 mg of the drug three times a day for six months, no dose-dependent side effects were found in obese patients.
Side effect of the drug
Today, many use for weight loss tablets "Listata Mini". Reviews of those who used this tool for weight loss indicate a risk of developing various side effects. Undesirable effect of the drug is manifested:
oily discharge from the rectum;
the discharge of gases with a small amount of discharge;
imperative urge to defecate;
steatorrhea;
abdominal pain;
fecal incontinence;
loose stools;
increased frequency of bowel movements;
minor bleeding from the rectum;
diverticulitis;
increased activity of hepatic transaminases ;
hepatitis
cholelithiasis;
bullous rash;
hypersensitivity reactions (itching, rash, urticaria, angioedema, bronchospasm, anaphylaxis).
Drug interaction
The simultaneous use of orlistat and cyclosporine can help reduce the concentration of the latter in blood plasma. In this connection, the simultaneous use of drugs based on cyclosporine and the Listata Mini medication is contraindicated.
The simultaneous use of orlistat and amiodarone leads to a decrease in the content of amiodarone in blood plasma.
The combined intake of orlistat and warfarin reduces the concentration of prothrombin and increases the INR rate. Therefore, taking “Listata Mini” and “Warfarin” or other oral anticoagulants at the same time is contraindicated.
Under the influence of orlistat, the absorption of fat-soluble vitamins A, E, D, K and beta-carotene may be reduced. If the doctor has prescribed multivitamins, it is recommended to take them 2 hours after the use of the Listata Mini medication.
Reception of orlistat leads to a decrease in the absorption of antiepileptic drugs, which can provoke the occurrence of seizures.
The combined use of "Listat Mini" and acarbose is not recommended, since no studies of this pharmacological interaction have been conducted.
In some cases, under the influence of the main active substance of the drug we are considering, the bioavailability of oral contraceptives may decrease. In severe diarrhea, additional methods of contraception should be used.
The simultaneous administration of orlistat and sodium levothyroxinoma can contribute to the development of hypothyroidism or reduce its control, since the absorption of inorganic iodine and sodium levothyroxine decreases .
The drug interaction of orlistat with substances such as amitriptyline, atorvastatin, biguanides, digoxin, fibrates, fluoxetine, losartan, phenytoin, phentermine, pravastatin, nifedipine, sibutramine and ethanol was not detected.
special instructions
The fundamental factors of weight correction are physical activity and proper nutrition. It is recommended that you start dieting and exercise before using the Listata Mini medication. Patient reviews confirm that by eating a low-fat diet, you can reduce the likelihood of adverse effects from the digestive tract.
Patients taking antiepileptic drugs should consult a specialist before taking the “Listata Mini” drug, as it is possible to change the severity and frequency of seizures. In this case, medications can be taken at different times.
Patients with kidney disease should also consult a doctor, as there is a risk of developing nephropathy and hyperoxaluria.
Due to weight loss while taking Listata Mini, patients with diabetes can normalize their carbohydrate metabolism. Therefore, before using this medication, it is necessary to consult a doctor regarding a reduction in the dose of hypoglycemic drugs.
With a decrease in body weight, blood pressure and cholesterol concentration may decrease. Patients taking lipid-lowering and antihypertensive drugs should consult a specialist. If necessary, he will adjust the dose of these drugs.
With the development of undesirable symptoms such as fatigue, weakness, fever, dark urine, you should consult a doctor to rule out impaired liver function.
How much does Listata Mini cost?
This drug can be bought in almost all pharmacies in Moscow and the Moscow region. Also, the Listata Mini medication (the price of the product is in the range of 1300-1500 rubles for 60 tablets) couriers of online pharmacies can deliver to the door of your house. However, be careful and beware of fakes.
Conclusion
Patients who took the drug "Listata Mini", reviews leave both positive and negative. It all depends on the state of human health and the individual characteristics of the body. In any case, never prescribe yourself medications yourself, including the Listata Mini weight correction product. Reviews of losing weight, of course, will help determine the choice of a particular medicine, however, start taking medications only on the recommendation of an experienced specialist.