In the fight against diseases of infectious origin, antibacterial drugs are most often used. One of the most commonly prescribed and popular antibiotics today is Tinidazole. The drug has proven to be highly effective in the treatment of diseases caused by various pathogens, including fungi and protozoa. Previously, this drug was used by specialists in the field of gynecology. However, to date, its scope has become wider and it is prescribed for infections of various origins. Instructions for use with Tinidazole will be described in detail in our article.
Structure
The drug is made in the form of tablets in an enteric-soluble membrane, in a dosage of 500 mg. The active ingredient in the drug is tinidazole. It adversely affects harmful bacteria, namely anaerobic microbes that can survive without oxygen, as well as pathogenic fungi and simple organisms.
The properties
Entering into interaction with the causative agent of infection, Tinidazole disrupts the bacterial DNA chain. The active component of the drug is rapidly absorbed from the gastrointestinal tract into the bloodstream. The drug has a cumulative effect and the peak of its therapeutic concentration in the body is achieved 2-3 days after the start of administration. This is confirmed by the instructions for use. Tinidazole for men is also effective.
Women during lactation should take it with caution, since the active substance passes into breast milk, which can affect the baby. Under the bactericidal effect of the drug, many strains of microorganisms fall. However, experts emphasize that a particularly high degree of effectiveness of the drug is manifested in the treatment of pathologies that are provoked by the multiplication of parasitic protozoa, for example, lamblia, trichone and amoeba. The listed infectious pathogens, as a rule, are difficult to treat, however, Tinidazole has proved its effectiveness in the destruction of precisely these microorganisms.
Indications
According to the instructions for use with Tinidazole, the indications for its use are quite extensive. However, the main diseases in which this drug is prescribed are:
- Hepatic amoebiasis.
- Dysentery caused by amoeba.
- Giardiasis
- Cutaneous leishmaniasis.
- Trichomoniasis
- Pneumonia.
- Infectious diseases of the soft tissues.
- Infections in the wounds.
- Sepsis.
- Peritonitis.
- Thrush.
- Infections after surgery.
- Fungus on the nails.
- Piosalpinx.
- Lung abscess.
- Vaginitis.
- Endometritis.
- Ulcerative gingivitis.
As indicated by the instructions for use with Tinidazole tablets, they are prescribed for the treatment of gastric infection, which occurs against the background of Helicobacter pylori infection. The drug is included in the complex therapy together with antibiotics and bismuth-based drugs.
Contraindications
It is strictly forbidden to take the drug in the first trimester of pregnancy, when there is an active stage in the formation of internal organs and systems of the fetus. After the first trimester, prescribing the drug is permissible with caution only if the effect of the therapy exceeds the potential risk of taking it.
Another contraindication for the appointment of "Tinidazole" is the lactation period. If taking the drug is unavoidable, then breastfeeding for the treatment period is canceled. You can resume lactation three days after taking the last antibiotic tablet.
It is not recommended to take "Tinidazole" for diseases of the central nervous system of organic origin, as well as for impaired hematopoietic function in the body.
Also, the restriction on admission is imposed with an allergic reaction to tinidazole, as well as for patients whose age has not reached twelve years.
Side effects
According to the instructions for use with Tinidazole, there are a number of undesirable reactions that may occur while taking such a potent antibacterial drug. The drug is not always well tolerated by patients. The following side effects are most common:
- Central nervous system: impaired coordination of movements, convulsive syndrome, dizziness, tremor of the extremities, damage to nerve fibers of a degenerative form.
- Dyspeptic symptoms, manifested by nausea, diarrhea, dryness and an unpleasant aftertaste in the mouth.
- Hematopoietic system: increased white blood cell count.
- Allergic reactions: rash on the body, Quincke's edema.
Overdose
Cases of drug overdose were reported very rarely. If this dosage is exceeded, diarrhea, vomiting, and pain in the abdomen may occur. If such symptoms are detected, symptomatic therapy is carried out, antidotes for this substance have not yet been found. It should be noted that such intoxication does not cause irreversible consequences for the body and, as a rule, an overdose is treated until complete recovery. It is also described in the instructions for use with Tinidazole (500 mg).
Drug interaction
If we talk about the interaction with other drugs, then it can be taken simultaneously with other antibacterial drugs, as well as sulfonamides. Do not use Tinidazole in combination with anticoagulants, as this can cause bleeding.
It is also forbidden to combine taking tablets with alcohol, since the active component of the drug interacts with ethyl, and also provokes a deterioration in the patient's condition. This is manifested by headache, facial flushing, nausea, shortness of breath and decreased blood pressure.
Instructions for use with "Tinidazole"
Adult patients are prescribed up to 4 tablets per day. In childhood, the dosage is calculated individually taking into account the weight of the small patient.
The duration of the course depends on the nature of the disease. When taking more than a week, you must regularly take a general blood test to monitor white blood cell counts.
The treatment of trichomoniasis requires the use of "Tinidazole" not only directly by the patient, but also his sexual partner. Alcohol intake should be excluded not only for the entire period of treatment with the drug, but also for another three days after the end of the course. The drug can affect the psychomotor functions of the body, so you should not drive a car or do work that requires an increased concentration of attention during treatment. This information contains instructions for use with Tinidazole (500 mg).
Price and analogues
It is permissible to store the drug at a temperature not exceeding 25 degrees. Shelf life is three years from the date of manufacture. The drug is not expensive and is available in pharmacies at a price of about 30 rubles. Instructions for use with "Tinidazole" analogues, unfortunately, does not describe.
There are a number of medicines, which include the same active substance:
- Tiniba.
- "Fazizhin."
- Tinaprot.
- "Tinidazole Acre."
- "Vero-Tinidazole."
- Tizol.
The therapeutic effect of all of the above drugs is similar to the original tablets. In addition to generics, there are also drugs similar to "Tinidazole", which identically affect the body. The closest in action is Trichopol. It includes metronidazole. However, it should be borne in mind that Trichopolum is more toxic than Tinidazole. Its use is less safe and increases the risk of side effects. The advantage of Trichopolum is the absence of influence on the concentration of attention and reaction rate. It can also be taken in combination with anticoagulants. The drug is also available (in addition to tablets) in the form of a suspension and vaginal suppositories. However, the cost of drugs based on metronidazole is several times higher than Tinidazole.
Reviews
Tinidazole is recognized by patients as an effective drug in the treatment of infectious diseases. Many note that he quickly helped to cope with inflammatory problems in the reproductive system. The antibacterial effect begins after a few days of admission, so long-term treatment is not required.
There are also reviews of "Tinidazole" in the treatment of giardiasis. These simple microorganisms cause intestinal and digestive upsets. For many patients, the drug helped to quickly eliminate the invasion. However, some comments suggest that Tinidazole is outdated and does not help against giardia, since microorganisms have developed immunity to the active substance of the drug.
Also, negative reviews contain information about side effects that occurred while taking the drug. The most common dyspeptic symptoms. Therefore, the best option is its simultaneous administration with preparations of the prebiotic group, which protect the intestinal microflora.
We reviewed the preparation "Tinidazole" instructions for use and reviews.