In the article, we consider the instructions for use for the Mexiprim preparation.
It is a drug that has a pronounced antioxidant effect. Against the background of its use, the body's resistance to stress increases, its resistance to physical loads. The drug is able to provide parts of the brain that suffer from oxygen deficiency by restoring blood supply. As a result, the patient has an increased ability to perceive information, concentrate, and improves memory. In addition, the medication has the ability to lower blood cholesterol.
Analogues of Mexiprim are not indicated in the instructions for use, we will consider them below.
Pharmacological forms
Manufacturers produce the drug in two pharmacological forms:
- Tableted Mexiprim.
- A solution intended for intravenous administration.
Composition, description
According to the instructions to Mexiprim, its solution is transparent, has a yellowish or white hue. The main active component in its composition is 50 mg of ethylmethylhydroxypyridine succinate. An additional component is purified water.
The mexiprim tablet contains 125 mg of the active ingredient. As auxiliary ingredients are used: microcrystalline cellulose, povidone, sodium carboxymethyl starch, talc, calcium stearate, kaolin. The tablets are coated with a film membrane made of hypromellose, titanium dioxide, macrogol and talc.
Pharmacological group
As indicated by the instruction, Mexiprim refers to heteroaromatic antioxidants. The medication has a wide medicinal activity: it is able to exhibit anxiolytic effect, which is not accompanied by the effect of muscle relaxation. Against the background of his admission:
- The toxic effects of alcohol are reduced.
- The efficiency of the body, the ability to concentrate is increasing.
- Antihypoxic and antioxidant function is manifested.
- There is an anticonvulsant effect.
- Increases the ability to assimilate information.
- The likelihood of developing memory impairment is reduced.
- A nootropic effect develops.
- The body's ability to withstand stress increases.
Active components are able to increase dopamine levels, provide an increase in aerobic glycolysis, and reduce the inhibition of oxidative processes in the Krebs cycle.
Indications for use
The Mexiprim instruction recommends use if the patient has the following disorders or conditions:
- Acute intoxication with drugs of the group of antipsychotics.
- Withdrawal syndrome accompanying alcohol addiction.
- The syndrome of anxiety is pronounced.
- Neurosis-like conditions, neurosis.
- Accompanying atherosclerosis cognitive impairment.
- VSD.
- Encephalopathy
- Acute circulatory disorders in the brain.
In adult patients, following the recommended treatment regimens, the medication is well tolerated. Use it if the patient has marked liver and kidney dysfunctions. The instruction for use with Mexiprim confirms this.
Clinical studies on the possibility of using the drug in the treatment of pediatric patients have not been conducted. Reliable data showing the mechanism of action of the main component of the drug on the children's body is currently not available, in this regard, the use of the drug by patients of this age category is prohibited.
Next, consider what else the instruction tells us. Reviews about Mexiprim, it is worth noting, mostly positive.
The use of the drug by pregnant and lactating women is strictly prohibited. Clinical studies of the influence of the active component on fetal development have not been conducted. If there is a need to use the product as a nursing woman, you should first transfer the child to artificial feeding.
The instruction for Mexiprim is very detailed.
Contraindications
Do not use the medication if the patient has the following disorders and physiological conditions:
- Childhood.
- Pregnancy.
- Lactation.
- Individual hypersensitivity to the components of the drug.
Caution should be exercised when prescribing a medication to patients with impaired liver and kidney function.
Using
In accordance with the instructions for use with Mexiprim, the tablet should be taken orally. Drink tablets should be in sufficient quantities with water.
When treating adult patients per day, the use of two tablets is indicated. If the expected therapeutic effect is absent, a dose increase of up to 800 mg per day is allowed. The maximum daily dose is recommended to be divided into 4 doses.
The optimal duration of treatment is considered to be a 2-month course of therapy, however, it may vary depending on the indications and recommendations of a specialist.
Using it during pregnancy can provoke a violation of the natural development of the fetus. During lactation, the drug is also prohibited for use.
Instructions for use with Mexiprim must be strictly observed.
Negative impact
If the patient complies with the dosage regimen recommended by the doctor, the probability of developing negative effects is extremely low. In the presence of individual susceptibility to the active substance, undesirable effects may develop, such as:
- Swelling of the skin.
- Redness of the skin.
- Hives.
- Depression.
- Apathy.
- Lethargy.
- Quincke's edema (in extremely rare cases).
- Drowsiness.
- Decreased appetite or its complete absence.
- Abdominal pains.
- Flatulence.
- Nausea.
- Dry mucous membranes in the oral cavity.
This is confirmed by the Mexiprim preparation instructions for use and reviews. If any of the indicated or not noted negative symptoms appears, the patient should inform the doctor.
Interaction with other medicines
As we are informed by the instructions for use with Mexiprim, it is allowed to use it in parallel with psychotropic drugs. The medication is able to increase the therapeutic effect of sedatives, and therefore dose adjustment of the latter is required.
Special instructions for use
The use of Mexiprim for the treatment of pediatric patients is strictly prohibited. It should not be used in the treatment of adolescents. During pregnancy, it is recommended to refrain from taking this medication. This is primarily due to the fact that the mechanism of the influence of the active component in the composition of the drug has not been fully studied. It is assumed that the drug is able to influence the speed of psychomotor reactions, in connection with which it is recommended to completely abandon or significantly limit the activity associated with driving vehicles and complex mechanisms.
What else can you learn from the instructions for use with Mexiprim?
Overdose
If the patient uses the drug in strict accordance with the recommendations of a specialist, then the likelihood of overdose cases is extremely low. If an overdose nevertheless occurs, then it is expressed in an increase in negative effects. The main manifestation of an overdose of Mexiprim is severe drowsiness. To eliminate such a manifestation, it is necessary to conduct a patient gastric lavage and stop using the medicine. The specified symptoms in this case disappear within a day. If digestive upset occurs, symptomatic therapy should be prescribed.
So it is said in the instructions for Mexiprim tablets.
Terms of sale and storage
A drug is a prescription drug. That is, to purchase it in a pharmacy you will have to present a prescription from a doctor. Storage of Mexiprim should be carried out in a place that is protected from the penetration of sunlight, and the ambient temperature should not exceed 30 degrees. It is important to prevent children from accessing the drug.
The maximum period during which the medicine retains its therapeutic properties is 4 years. If the drug has expired, its use becomes unacceptable.
We will not consider in detail the instructions for the analogues of Mexiprim.
Analogs
If necessary, the drug can be replaced with a similar tool. The most popular drugs with a similar effect are:
- "Cytoflavin." It is an analogue of Mexiprim in the pharmacological group. The manufacturer produces the drug in tablet and injection form. Against the background of the use of the medication, the metabolism in the brain tissues improves. It is allowed to use “Cytoflavin” in pediatrics, even in the treatment of newborns, which is an undoubted advantage over “Mexiprim”.
- "Ethoxidol". It is an analogue of "Mexiprim" in the therapeutic group, is an antioxidant. The manufacturer produces the medicine in the form of tablets intended for chewing. Often prescribed for encephalopathy, cognitive impairment, ischemic strokes, coronary heart disease.
- Mexi B6. It is a combined medication in which, in addition to ethylmethylhydroxypyridine succinate, contains pyridoxine. These active components are able to enhance the effect of each other, which greatly expands the scope of the drug. For example, it is often used as a prophylactic against attacks of coronary heart disease.
- Mexidol. It is a reference drug of domestic production. The main active ingredient, as in Mexiprim, is ethyl methyl hydroxypyridine succinate. The medication has undergone extensive clinical trials, which made it possible to accurately determine the likely therapeutic effect of its use, as well as negative reactions. As auxiliary components, Mexidol uses substances other than Mexiprim.
Cost
On average, one package of Mexiprim will cost 370 rubles. However, the cost may fluctuate depending on the pricing policy of the pharmacy chain that distributes it, as well as the region of sale. So, the price of Mexiprim in some pharmacies can reach 1070 rubles.
This information is not contained in the instructions for use with Mexiprim tablets.
Usage Reviews
In various sources there is a mass of a wide variety of reviews about the experience of using various pharmacological forms of Mexiprim. Moreover, these reviews, for the most part, are contradictory. Some patients note the high effectiveness of the drug, while others report its complete uselessness. This is due, first of all, to the fact that Mexiprim is not suitable for all patients equally. Accordingly, it is not possible to give an objective assessment of its therapeutic effectiveness.
It is important to remember that the appointment of any medication, including Mexiprim, should be carried out by a specialist. This will achieve the best effect of therapy, as well as prevent the occurrence of negative effects.
We reviewed the Mexiprim preparation instructions for use, reviews and analogues.