The international name of the drug "Nise", reviews of which are distinguished by surprising unanimity, is "Nimesulide", by the name of the active substance.
The drug is available in many dosage forms. In our country you can buy:
• Granules for the preparation of a drinking solution
• Granules for the preparation of a suspension intended for internal use
• Tablets: for resorption, soluble in water, ordinary
• Ready suspension
• Gel for external use
"Nise", reviews of doctors and patients about which in most cases are positive, is intended to relieve pain symptoms with radiculitis, neuralgia, myalgia, ankylosing spondylitis. Nimesulide is prescribed for soft tissue diseases, post-traumatic pains, dysmenorrhea, traumatic inflammation of the musculoskeletal system. It relieves pain in the spine, reduces fever and alleviates the condition for infectious diseases. All dosage forms of the drug have an antipyretic, anti-inflammatory effect. It inhibits the synthesis of the enzyme cyclooxygenase type 1 and 2, which, in turn, reduces pain and inflammation.
"Nimesulide" or "Nise" (doctors' reviews coincide with the test results of the drug) is strictly contraindicated:
• With exacerbations of ulcers, other diseases of the gastrointestinal tract
• Bleeding of the stomach, intestines
• Asthma, a reaction to Aspirin
• Patients with hepatic or renal failure
• For diabetes (sugar) type 2
• Pregnant, lactating women
• Suffering high blood pressure
• Children under two years old
Regardless of the form of release, Nise (reviews of doctors and patients confirm this) can cause side effects. Among them, a sharp headache, anaphylactic shock, other allergic reactions, nausea, diarrhea, heartburn, vomiting. The drug can increase transaminase levels, cause gastrointestinal ulcers, gastralgia, and fluid retention in the body. Significantly less often , Nise tablets (reviews and research results coincided in this case as well) cause hematuria, leukopenia, thrombocytopenia.
So is it worth it to use a medicine that has such widespread side effects. The answer is simple: without prescribing a doctor, drug treatment is excluded.
Only a doctor is able to recommend the “correct” form of the medical “Nise”, to choose its dosage.
Children from two to 12 years old are often prescribed a suspension, adults - tablets of various kinds. In children, the dosage of Nimesulide should not exceed 1.5 mg per kilogram of weight. Give the drug three times (sometimes twice) per day.
The daily dose of adults is 200 mg, divided into two doses.
The least safe is the Nise Gel. Reviews report that it perfectly relieves pain and inflammation, without causing side effects.
"Nimesulide" from the gel very quickly penetrates into the tissues, joints and capsules of the joints, bypassing the bloodstream. It suppresses pain mediators produced in the focus of inflammation. This non-steroidal anti-inflammatory drug quickly relieves swelling or swelling of the joints, inflammation, pain. In addition, it relieves joint stiffness, bone pain. Nise is an Indian preparation. It has analogues that are produced in other countries. This is "Aktasulid", which is produced in Serbia and Montenegro, "Aulin", produced in Ireland.
Nimesulin is the active substance "Aponila" (Cyprus), "Nimegesika", "Nimulida", "Nimika", "Prolida" (India), "Flolida" (Italy).
Despite the fact that all of the listed drugs have a similar effect, it is not recommended to replace them with each other without the recommendation of doctors: a medicine of different manufacturers may differ in details.
In general, the Nise drug (tablets, suspensions, gel) is recognized by medical personnel as an excellent tool for treating inflammatory diseases and relieving pain symptoms. It is important only to take it correctly, based on the advice of a doctor.