The diagnosis of uterine fibroids in many women causes panic. Many believe that the disease belongs to the oncological group. In fact this is not true. Myoma is a benign formation that can be easily eliminated with the help of drug therapy. If a woman does not consult a gynecologist in a timely manner, surgery may be necessary. So that surgery is not necessary, it is worth taking Esmiya tablets. Reviews show that the drug helps reduce the size of fibroids in just one course.
Release form, packaging and composition
The medicine has the form of white biconvex tablets. The main active ingredient is ulipristal acetate. One tablet contains 5 g of this substance. As auxiliary elements are used: microcrystalline cellulose, talc, mannitol, croscarmellose sodium, as well as magnesium stearate. The drug is offered in pharmacies in cardboard packaging.
Ulipristal acetate can be classified as a selective stimulant of progesterone receptors. A partial antiprogesterone effect in the tissues is also observed. The most active drug is when taken orally. The main substance acts directly on the endometrium. If the course of treatment begins at the beginning of the menstrual cycle, bleeding in many patients does not occur. The cycle is usually restored within a month after the end of therapy.
The drug also affects the pituitary gland. Ovulation does not occur in most patients who take Esmiya (tablets). Reviews show that it is almost impossible to get pregnant during treatment. The level of progesterone in the blood of a woman is significantly reduced.
Indications
Esmiya tablets are prescribed for patients of reproductive age (over 18 years old) with the appearance of symptoms of uterine fibroids of mild or moderate severity. The medicine is used as preoperative therapy. If treatment fails, surgical intervention is considered.
A woman should first of all pay attention to such unpleasant symptoms as heavy bleeding during menstruation, as well as an unstable cycle. If pain occurs in the lower abdomen or in the lumbar region, you should immediately consult a gynecologist. The specialist can diagnose only after analysis and ultrasound examination.
Contraindications
Without the recommendation of a specialist, you should not take the drug "Esmiya". Reviews of doctors show that the medicine has many contraindications. These include primarily bleeding of unknown etiology. The specialist must determine the exact diagnosis. At risk are patients whose bleeding occurs several times per cycle. No drug is also prescribed for cancer. You need to make sure that the patient does not have cervical or ovarian cancer.
A contraindication to the appointment of Esmiya tablets is a severe form of bronchial asthma. The problem is that medications to maintain a normal state of the patient most often have a hormonal nature. The combined use of several drugs based on hormones can lead to the development of side effects.
Some may cause hypersensitivity to the Esmiya drug. Reviews show that even with a small dosage, an allergic reaction develops. Therefore, if any extraneous symptoms appear, treatment with tablets should be discontinued.
Taking the drug during pregnancy
Medicines, the main active ingredient of which is ulipristal, are contraindicated during pregnancy. There has been very little research in this area. Therefore, data on the intake of Esmiya tablets by women during pregnancy are limited.
Animal studies have shown that the main active substance is excreted in breast milk. Therefore, during lactation, it is also undesirable for patients to take the Esmiya remedy. Reviews of doctors show that ulipristal may be too toxic for a newborn.
special instructions
Only after a thorough examination can the drug “Esmiya” be prescribed. Reviews of gynecologists make it possible to understand that the medicine gives good results after an accurate diagnosis. In addition, pregnancy should be ruled out before starting therapy. Due to the possibility of interaction with other hormonal drugs, doctors recommend not using hormonal contraceptives during therapy. Other methods of protection against unwanted pregnancy should be used.
With caution, the medicine is taken by patients with renal failure. Patients with a severe form of the disease should treat uterine fibroids in a hospital under the supervision of specialists. Otherwise, the Esmiya medicine can lead to severe toxic poisoning. Reviews of doctors show that trouble can be avoided if the dosage is adjusted on time.
Patients should always be informed about what leads to a decrease in bleeding treatment with Esmiya tablets. Reviews show that during therapy, menstruation is generally absent. Therefore, with the appearance of significant spotting, you should immediately contact a gynecologist.
Dosage
To achieve the maximum result, the Esmiya medicine should be taken correctly. Reviews show that the exact dosage in each case can only be determined by a doctor. Therapy is long. Patients take initially one tablet per day for several months. The maximum course of therapy can last 3 months. If symptoms of uterine fibroids occur, treatment can be resumed after some time.
The drug should be taken strictly according to the regimen (preferably at the same time). The use of tablets does not depend on the diet. The patient can independently determine when she should drink Esmiya tablets. Reviews show that the medicine has the most beneficial effect when used in the afternoon.
Dosage adjustment is required in patients with severe renal failure. Treatment is carried out only in a hospital setting. Data on an overdose of the drug by patients without chronic diseases are practically absent. Experts suggest that tablets in large quantities can cause acute poisoning.
Side effects
Studies have been conducted on the safety of taking Esmiya tablets by women of reproductive age. The most common side effect was the appearance of hot flashes. Representatives of the weaker sex at the same time felt severe discomfort. But such a symptom does not require a dosage adjustment. In addition, hot flashes most often occur only in the first weeks of therapy.
Some patients experienced minor mental disorders during treatment. Women felt anxiety and anxiety. But treatment does not lead to a depressive state. Therefore, the abolition of therapy is not required.
Hypersensitivity is also considered a fairly common occurrence. This condition occurs in 5% of patients and manifests itself in the form of allergic reactions. Patients may develop a skin rash and itching. Puffiness of extremities is less often observed.
Drug interaction
Ulipristal acetate has a steroid structure and acts on the body as a selective stimulant. Therefore, it is not recommended to drink the Esmiya drug (tablets) together with hormonal contraceptives. Reviews show that they significantly increase the likelihood of pregnancy. At the same time, the effectiveness of the drug intended for the treatment of uterine fibroids decreases.
Co-administration with a
proton pump inhibitor can affect the pH of gastric juice. It is especially important for patients with gastritis to know. Drug interactions can lead to ulcers.
Are there any analogues?
If, for a number of reasons, it is not possible to take ulipristal-based medicines, you can always find an alternative. The gynecologist will tell you how you can replace the Esmiya medicine. Analogs, reviews - all this can be found in the antenatal clinic. As a medicine for the treatment of uterine fibroids, Norkolut tablets are often used. The main active drug is norethisterone. Additionally, components such as potato starch, silicon dioxide colloidal, lactose monohydrate, gelatin and talc are used.
Tablets can be used to treat uterine fibroids in women of reproductive age. Also, the drug is indicated for gynecological diseases such as anovulatory metrorrhagia, endometrial hyperplasia, endometriosis. In addition, the medication can be used to
stop lactation or prevent the allocation of breast milk for medical reasons. Independently (without consultation with a gynecologist) tablets should not be used.
Reviews about the drug "Esmiya"
Experts note that the Esmiya drug shows really good results if the patient promptly seeks help. Usually a course of 2 months is enough to completely remove the symptoms of the disease. At the same time, gynecologists note that the use of tablets is strictly on the recommendation. The problem is that they have many contraindications. Incorrect treatment can be harmful.
Patients note that the tablets have almost no taste. Therefore, their reception does not cause discomfort. The drug helps to avoid surgery, which can not but rejoice.
Where to buy and how much?
Only the prescription Esmiya drug is released. Instructions, reviews - all these questions should be clarified by a doctor before contacting a pharmacy. The medicine is common. Therefore, its acquisition is not difficult. Esmiya tablets belong to the group of expensive medications. For one package you will have to pay at least 10,000 rubles. You can save a little if you order the medicine in real time. Tablets are offered in almost every online pharmacy.