Adults and seniors are quite often troubled by heart disease, one of which is ischemia. Often people experience shortness of breath, dizziness, or tinnitus. The Triduktan remedy can help get rid of unpleasant symptoms and cope with the disease.
The drug "Triduktan" application instructions defines as anti-ischemic and antihypoxic drug. It is used for cardiological, ophthalmic, as well as for otolaryngological diseases.
Composition and form of release
Triduktan and Triduktan MV are available in the form of coated tablets. The main active ingredient is trimetazidine dihydrochloride. The composition of the tablets "Triduktan" includes 20 mg of active substance. The medicine "Triductan MV" includes 35 mg of the active substance. As you can see, the active component is the same, therefore, the properties, indications, contraindications and side effects of the drugs are the same.
Triduktan MV (35 mg) also consists of excipients. They are microcrystalline cellulose, mannitol, glycol montan wax, magnesium stearate, and type B methacrylate ammonium copolymer. The drug at a dosage of 20 mg also has auxiliary substances such as corn starch, polyvinylpyrrolidone, mannitol, talc, magnesium stearate. A medicine with a dosage of 20 mg has two numbers - 30 and 60. These figures show the number of tablets that are in a cardboard box. The drug at number 30 includes 3 blisters with tablets, in each blister 10 tablets. The medicine with a dosage of 35 mg belongs to number 60. "Triduktan MV" No. 60 is available in a cardboard package, which contains 6 blisters of 10 tablets.
Pharmacological properties
The main constituent substance, trimetazidine, has an effect on cellular metabolism, thereby preventing ATP levels from decreasing under hypoxia. The medicine normalizes the energy balance in the cells and, by regulating the function of ion channels in the cell membranes, supports cell homeostasis. Thanks to this drug, the process of glucose oxidation is stimulated, and the process of fatty acid oxidation is suspended. Due to this, the energy metabolism of the heart muscle is supported. "Triductan" helps prevent the development of intracellular acidosis. Due to trimetazidine, the infiltration and migration of reperfused and ischemic heart muscles is reduced. In addition, Triduktan increases coronary reserve, reduces angina attacks. Thanks to the drug, the need for nitrates for patients with ischemia is reduced.
Indications for use
"Triductan" is used in cardiology for long-term therapy of coronary artery disease, as well as for the prevention of angina attacks in combination with other drugs. Also, the medication is used in ophthalmology for chorioretinal disorders of ischemic origin. In addition, the drug can be used in the treatment of vestibular disorders of ischemic origin as well, for example, hearing loss, dizziness or tinnitus.
Contraindications
The drug is contraindicated in case of hypersensitivity to any components of the drug. You can not take "Triduktan" and people who suffer from severe impaired liver and kidney function. During pregnancy and lactation, the drug should not be taken. It is undesirable to use it for children under 18 years of age, since there is no data on the safety of this drug at this age.
Adverse reactions
Despite the fact that patients are usually well tolerated with the drug "Triduktan", the instructions for use warns of possible adverse reactions. On the part of the nervous system, a side effect such as dizziness or headache may appear. Muscle hypertonicity and akinesia, various motor disorders, such as gait instability, are also not excluded. In addition, sleep disturbance is possible. It can be either drowsiness, or, conversely, insomnia.
Cardinal and vascular disorders are also possible. These include tachycardia, extrasystole, palpitation, orthostatic and arterial hypotension, which can manifest as redness of the face and general malaise.
From the digestive tract, pain in the stomach, as well as nausea, vomiting, constipation or diarrhea, may occur. There are also various skin reactions, such as itching, rash, swelling, or urticaria. Common disorders include asthenia and angioedema.
Overdose
The therapeutic range is quite large, this gives a low likelihood of intoxication of the body with the drug "Triduktan". Instructions for use highlight some of the symptoms of an overdose of this medication. These include redness of the face, arterial hypotension, as well as increased side effects. In case of an overdose, symptomatic treatment is necessary.
Dosage and administration
This drug is taken orally, along with food. Take "Triduktan" should be one tablet three times a day, "Triduktan MV" - one tablet twice a day, preferably in the morning and at night. Drink the tablets with plenty of water. This medicine is used for a rather long time. The course of treatment is determined by the doctor individually for each patient, depending on how the disease progresses. The treatment regimen can be adjusted if necessary after a couple of months.
It should be borne in mind that Triduktan must be taken in a course, and not just to suppress angina attacks. When treating elderly patients, the dosage regimen does not need to be changed.
Patients who have moderate impaired renal function, need to take the drug 2 times a day, 1 tablet (20 mg). Elderly people should also take the drug 2 times a day.
Special instructions
It should be borne in mind that to suppress angina attacks do not take "Triduktan". Instructions for use also warns that this drug is not prescribed as primary therapy for myocardial infarction or unstable angina. If during treatment there are bouts of unstable angina, the course of the disease should be reviewed and treatment should be adjusted.
The drug must be discontinued if there is the appearance of motor disorders, such as gait instability, tremor. After discontinuation of the drug, symptoms should disappear in a maximum of 4 months. If symptoms persist, you need to visit a neurologist.
The medicine "Triductan" has no effect on hemodynamics. But side effects such as dizziness and drowsiness can affect driving or working with machinery. Therefore, the use of this drug is not recommended in this case.
Drug interaction
Data on interactions with other drugs are as follows. Trimetazidine can be prescribed in parallel with drugs such as heparin, acetylsalicylic acid, calciparin, beta-blockers, lipid-lowering drugs, a calcium antagonist, and also with digitalis drugs. It should be noted that trimetazidine does not affect the plasma level of digoxin.
Drug storage
The drug must be stored in a place inaccessible to the child. Storage temperature should not exceed 25 degrees. The medicine must be stored in its original packaging for a shelf life of 24 months.
Triduktan: price and vacation at the pharmacy
The price of the drug "Triduktan" depends on several factors, primarily from the manufacturer and transportation. In pharmacies, the cost ranges from 300 to 400 rubles. In pharmacies, you can also buy Triduktan MV. Its price is two times higher - about 600 rubles. The cost of the drug is considered average, but you should not try to buy it without consulting a doctor, as you can harm your health and waste money, albeit small ones.
Analogues of the drug
An analogue of this medicine may be needed if it is not available in the pharmacy, as well as if the price does not suit. Pharmacists most often offer several analogues of the drug "Triduktan", the price of which, however, can be either lower or higher than this remedy. The main substitutes are Trimetazide, Rimekor, Preductal MV, Metazidine, and Tricard.
Reviews about the drug
Mostly reviews about this drug are positive, but there are very few of them, so it's hard to judge whether the drug is good or not. Patients who have experienced ischemia are grateful to the drug for recovery. People with tinnitus and dizziness experienced an improvement when taking Triduktan. But there are also negative reviews. A small percentage of people claim that the drug is completely useless and does not improve health. Also, reviews of some people report that the improvement came after two weeks of treatment. The instruction indicates that the drug should be used for a long time, so you should not expect any changes on the next day of taking Triduktan. The responses of the athletes are completely different. They claim that a pill drunk before training improves physical condition, even with high loads shortness of breath does not appear. This suggests that the drug still has an effect from the first dose. It can be concluded that the reviews about the drug are quite contradictory, therefore it is better to take it with caution.
It should be remembered that one way or another, this drug has an effect on the heart and, if improperly dosed, can harm the body, so you must read the instructions and consult a doctor before use.