In the article, we consider the instructions for use with "Panzinorm1 10000", as well as reviews about the tool.
This medication from the category of multienzyme preparations is classified as therapeutic drugs that can selectively affect specific receptors. The active enzymatic composition of this drug completely compensates for the lack of pancreatic enzymes, eliminating digestive system problems. Consider further the instructions for using this medicine, in addition to find out what analogues it currently has and what people write in reviews.
Description of the medication
According to the instructions for use, Panzinorm acts as a combination medicine, whose composition includes optimally balanced pancreatic enzymes that provide high-quality digestion and absorption of proteins, fats and carbohydrates in the intestine. This drug is used with great success to treat all kinds of digestive disorders in adult patients and in young children.
Lipase along with protease and amylase, which are part of this enzyme drug, are extracted from the tissue of the pancreas of cattle, as well as pigs. These components are completely natural and balanced for the human body. The tablets, exactly like the Panzinorm capsules, are coated with a special acid-resistant coating, which guarantees the release of enzymes directly in the intestine. Enzymes, as a rule, begin to act after the dissolution of the protective shell.
So, then we will figure out in which cases it is advisable to use this drug for treatment.
Indications for use
As indicated by the instructions for use, Panzinorm stimulates the enzymatic secretion of the pancreas. It is worth noting that the deficiency of enzymes is very noticeable in diseases that are accompanied by impaired digestion functions. Thus, it is advisable to take this drug for diseases such as chronic pancreatitis, inflammation of the digestive system, cystic fibrosis, as well as for overeating, dysbacteriosis and flatulence, and against the background of surgery for gastroectomy or pancreatectomy.
The medication is prescribed immediately after the start of nutrition through the probe. It is prescribed to patients for intestinal degassing before performing x-ray and ultrasound diagnostics.
Instructions for use with Panzinorm confirms this.
Method of administration and dosage of medication
The dosage of this therapeutic agent should be selected by the doctor. At the beginning of treatment, the following recommendations remain:
- Take this drug either during or after a meal, one or two capsules three times for ten days. Later, the dose with the course is adjusted.
- Taking this drug for cystic fibrosis, as a rule, is correlated with body weight. For example, children under four years of age consume 100 PIECES of lipase per kilogram of body. Starting from four years, 500 units are taken for each food intake.
- According to the instructions for use with Panzinor, the maintenance dosage of this medicine should not exceed 10,000 units per day.
It is worth noting that the drug for the treatment of steatorrhea (this is an excess of fat in the feces) and ensuring a normal diet is usually taken in high dosages. Chewing the capsules of the drug is prohibited, since the contents of the medication lose their properties and can damage the oral mucosa. The protective coating is opened only for elderly patients and children, while enzymes are poured into liquid dishes. In order to avoid constipation, Panzinorm is washed down with plenty of water.
Side effects
According to the instructions for use, Panzinorm is rapidly absorbed, easily excreted from the human body and does not burden the liver. True, the immune system can respond to the drug with the appearance of a rash, itching, and at the same time lacrimation, bronchial spasms and nausea.
Digestive system malfunctions in the form of nausea, vomiting, abdominal cramps, constipation or diarrhea, flatulence, rashes on the skin around the anus or mouth. Often, at elevated dosages, Panzinorm in humans can cause narrowing of the lumen of the colon.
With a high dosage of enzymes, patients with cystic fibrosis may develop hyperuricemia, which is an increased content of uric acid in the blood. Less commonly, side effects are expressed in the formation of stones.
Panzinorm has some contraindications, we will consider them further.
Contraindications to the use of the medication
The presented drug is not used if the patient has an increased sensitivity to its active component and pork proteins. The medicine "Panzinorm" is not prescribed in a number of the following cases:
- Against the background of an exacerbation of pancreatitis, it is true that negative consequences during its use are extremely rare. This is possible only in one patient out of ten thousand.
- In the presence of a chronic form of pancreatitis in the initial phase of the acute period.
- Children under the age of three.
- Patients under the age of fifteen in the event that they suffer from narrowing of the colon.
The compatibility of this drug with alcohol is completely absent. In the case of drinking alcohol with Panzinorm, the therapeutic effectiveness is significantly reduced, and at the same time, side effects increase and drowsiness occurs along with lethargy. The medicine "Panzinorm" has no effect on the management of transport and sophisticated equipment.
Treatment duration
The therapeutic course "Panzinorm" lasts, as a rule, for several days in the case when it comes to short-term digestion as a result of malnutrition. In difficult cases, in the presence of a deficiency of natural nutrient components, this drug is taken from 3 months to one year.
So it is said in the instructions for use to the Panzinorm. Reviews and analogues of the medicine are of interest to many, but more on that later.
Interaction with other medications
This enzyme agent significantly inhibits the activity of the drug "Acarbose", which delays the digestion of carbohydrates in the small intestine and their absorption. When combined with the drug "Miglitol," the level of glucose in the blood decreases. The medicine "Cimetidine" lowers the secretion of hydrochloric acid. The combination with bicarbonates complicates the absorption of folic acid.
The active ingredients of the drug greatly complicate the absorption of iron, however, the clinical rationale for such an interaction has not yet been studied. In the case of a combination of Panzinorm with Omez, Losek and Lazak medicines, due to the excessive activity of pancreatin that accompanies the action of these drugs, the dosage of the drug is best reduced.
Drug overdose
There is currently no information regarding the general intoxication of the human body in case of an overdose of this drug. But it is known that an excess of the drug can cause nausea along with vomiting, diarrhea, hyperuricemia and uricosuria. In patients with cystic fibrosis, irritation of the perianal folds may occur. In case of an overdose, Panzinorm administration is stopped, the stomach is washed and appropriate treatment is carried out.
In the instructions for use, analogues of "Panzinorm 10 000" are not indicated. We will consider them below.
Storage conditions for the drug
The drug should be stored in an inaccessible and cool place, subject to a temperature regime of 25 degrees. The medicine should be kept in its original packaging, which protects the drug from moisture. Shelf life is usually three years from the date of issue.
Composition and format of the issue
The basic ingredient of this drug is pancreatin, which contains an extract from the mucous membrane of the stomach of livestock. Also in it there is an extract from cattle bile. Thus, the composition of the presented drug is as follows:
- Lipase is contained in an amount of 10,000 units. Instructions for use with Panzinorm 10 000 indicate that the ingredient breaks down fats, being a key factor in regulating the processes of digestion of products.
- Amylase is contained in the amount of 7200 units, this element breaks down carbohydrate dextrin.
- Potease is contained in an amount of 400 PIECES. This ingredient improves protein breakdown.
Also on sale is Panzinorm 20000. Instructions for use with it almost completely coincide with the drug we are describing, only the dosage changes.
The medicine also contains cholic acid along with pepsin and amino acid hydrochlorides, which are pancreatin biocatalysts. This drug immediately begins to affect the body as an pancreatic enzyme.
Excipients are cellulose, magnesium stearate, crospovidone, colloidal silicon dioxide, and, in addition, talc, macrogol and caramel sodium. In pharmacies, Panzinorm is sold in two formats: capsules and tablets with different concentrations of enzymes. The capsules of the drug are coated with a gelatin shell, which protects the enzymes from the damaging effects of the gastric juice.
In accordance with the instructions for use, Panzinorm Forte is available in the form of tablets coated with an enteric coating of white or slightly grayish color with a characteristic smell of vanilla. Tablets are packed in blisters of 10 pieces, 1 or 3 blisters in a cardboard box.
The composition of 1 tablet includes pancreatin or:
The auxiliary components are lactose monohydrate, microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate.
During pregnancy
The instructions that accompany this medicine do not contain any data on its safe use in the prenatal period and during breastfeeding. But this drug is prescribed when the mother's need for it is higher than the risks for the child.
"Panzinorm" is recommended for use if a woman during gestation or feeding has a serious malfunction in the digestion of food, which can be aggravated against the background of the development of chronic pancreatitis, as well as in the presence of liver problems.
Most often, Panzinorm 10000 is used . According to reviews and instructions for use, the medicine is quite safe.
Use in childhood
This drug is used in the field of pediatrics, taking into account its effect on the release of enzymes. Starting from three years, children are prescribed this medication in the amount of one or two tablets or capsules with meals. The duration of treatment is determined by the doctor based on the health status of young patients.
In the absence of treatment for exocrine pancreatic insufficiency, it can slow down the development of the child, which leads to all kinds of problems with bone tissue. In this case, the immune system is seriously disrupted.
Pharmacy dispensing conditions
For the purchase of this drug in a pharmacy, a medical prescription is usually not required. It is freely released to all comers.
Analogues of the drug
Panzinorm has some analogues that contain exactly the same active ingredients, these are drugs such as Mikrazim along with Pancreatin, Festal, Gastenorm, Enzistal, Penzistad, Creon, Hermitage, Mezim, and Pangrol. But if it is necessary to replace Panzinorm with one or another analogue, it is better to consult with your doctor.
Reviews about the drug
The reviews of people about Panzinorm are mostly quite positive. This combined enzyme remedy has become one of the most popular medicines. Patients noted good tolerability of the drug and its very high efficiency. As consumers write, allergic reactions along with side effects, with absolute observance of the rules of use, are extremely rare.
We reviewed the instructions for use with Panzinorm and analogues of the drug.