"Rigevidon" refers to the pharmacological group of oral monophasic contraceptives. It is used to prevent unwanted pregnancy in women of reproductive age. The article will feature reviews about Rigevidone. Instructions for use and side effects of the drug are of interest to many.
The drug is made in tablets. They are enteric coated. The composition of the medicine includes two active substances:
- Levonorgestrel.
- Ethinyl estradiol.
Also, the structure of the drug includes additional components, which include:
- Starch.
- Silica.
- Lactose.
- Talc.
- Calcium carbonate.
- Croscarmellose.
- Sucrose.
- Corn starch.
- Polyvinylpyrrolidone.
- Ethylene glycol polymer.
- The copolymer of 1-ethenylpyrrolidin-2-one and ethenyl acetate.
Tablets are packaged in blisters of 21 pieces.
Pharmacological properties
The therapeutic effect of "Rigevidon" is due to the active substances included in its structure:
- Levonorgestrel is a structural substitute for the hormone of the corpus luteum progesterone, and is slightly higher in activity. When penetrated into the body, it is not amenable to metabolism, inhibits the release of follitropin and peptide hormone from the hypothalamus, which inhibits the process of ripening and ovulation.
- Ethinyl estradiol is a estrogen substitute for women. Upon entry into the body increases the viscosity of the cervical mucus, which prevents the passage of sperm and improves the contraceptive effect, which is due to levonorgestrel.
After oral administration of the drug, its active substances are rapidly and completely absorbed into the bloodstream from the intestine. They spread throughout the tissues; the elimination half-life varies from two to seven hours.
Indications
Birth control pills “Rigevidon” are prescribed to prevent an unplanned pregnancy. In addition, they are used in premenstrual syndrome and to eliminate functional disorders of the menstrual cycle.
What limitations exist
A number of physiological and pathological conditions of the woman’s body are distinguished, which are considered medical prohibitions for taking Rigevidon. These include:
- Severe liver damage with the appearance of its functional failure.
- Hyperbilirubinemia (a lesion characterized by an increase in bilirubin in the blood).
- Gilbert's syndrome (a pigmented disease characterized by a moderate intermittent increase in free bilirubin in the blood as a result of impaired intracellular transport in hepatocytes to its junction with glucuronic acid, as well as a decrease in the degree of hyperbilirubinemia under the influence of phenobarbital and an autosomal recessive type of inheritance).
- Rotor syndrome (a rare pathological process that is congenital in nature and is characterized by moderate yellowing of the skin).
- Dabin-Johnson syndrome (enzymatic jaundice, a rare pigmented hepatosis, which is characterized by a violation of the excretion of bound bilirubin from hepatocytes into bile capillaries).
- Cholecystitis (inflammatory lesion of the gallbladder).
- Unstable angina pectoris (a period of coronary heart disease that threatens myocardial infarction).
- A stroke of the brain (a pathological process that develops after a sudden violation of the microcirculation of blood in nerve cells, which leads to their death).
- Myocardial infarction (one of the clinical forms of ischemic heart disease, which occurs with the appearance of ischemic necrosis of a portion of the heart muscle).
- Thromboembolism (acute blockage of the vascular bed by a thrombus, which is torn off from the place of formation on the wall of the heart or blood vessel and enters the bloodstream).
- Severe arterial hypertension (a disease in which sustained high blood pressure is noted).
- Endocrine pathology (a disease in which the normal functioning of the endocrine glands is disturbed).
- Diabetes mellitus (a group of endocrine lesions that are associated with impaired glucose uptake and arises as a result of absolute or relative insufficiency of the hormone insulin).
- A woman is over forty years old.
- Hyperlipidemia (a pathological process characterized by the accumulation of cholesterol in the blood).
- Anemia (hematological diseases, the common point of which is a decrease in hemoglobin in the blood, as a rule, with a joint decrease in red blood cells).
- Breast-feeding.
- Otosclerosis (a lesion characterized by a decrease in hemoglobin in the blood, more often with a joint decrease in the number of red blood cells).
- Bubble drift (pathological damage to the fetal egg, which is characterized by the transformation of the villi of the external germinal membrane into cysts).
- Pregnancy.
- Migraine (a neurological lesion, the most frequent and characteristic sign of which is episodic or constant severe pain in the head).
- Idiopathic jaundice (the result of diseases of the liver and other organs, which are manifested in staining of the skin, as well as mucous membranes and sclera in yellow).
- Itchy skin.
- Herpes (a viral lesion with a characteristic rash of grouped vesicles on the epidermis and mucous cavities).
- Individual intolerance to any of the substances of the drug.
What other contraindications and side effects does Rigevidon have?
Additional bans
A pharmacological drug is used with extreme caution in the following conditions:
- Tuberculosis (a disease of infectious genesis caused by mycobacteria).
- Nonspecific ulcerative colitis (an inflammatory process in which the mucous membrane of the colon is diffusely damaged).
- Uterine fibroids (formation and growth of a benign tumor in the myometrium).
- Mastopathy (benign disease of the mammary glands, which is caused by pathological proliferative growths in the tissues of the gland).
- Hypertension (a lesion in which there is a persistent increase in blood pressure).
- Intermittent porphyria (an affliction characterized by damage to the nervous system).
- Phlebitis (inflammatory lesion of the venous wall).
- Multiple sclerosis (a chronic disease in which the myelin sheath of the nerve fibers of the brain and spinal cord is affected).
- Epilepsy (a neurological ailment, which is characterized by a predisposition of the body to a sharp appearance of seizures).
- Minor chorea (a neurological lesion caused by promiscuous muscle cramps and motor impairment).
- Hidden tetany (involuntary muscle contractions that can be triggered by diseases that increase the potential for the frequency of muscle cells or nerves that innervate them).
Side effects of Rigevidon
From the instructions for use, it is known that sometimes when using tablets, certain negative manifestations are possible, which include the following conditions:
- Nausea.
- Intermittent gagging.
- Migraine.
- Breast engorgement.
- Decreased sexual desire.
- Weight gain.
- The appearance of bleeding.
- Dry sclera and cornea.
From the reviews and instructions to "Rigevidon" it becomes known that with prolonged use of the drug, jaundice can develop, as well as generalized cramps.
In addition, the appearance of chloasma, intravascular blood clots, an increase in blood pressure. In this situation, discontinuation of Rigevidon and examination by a doctor is required.
Method of admission
Rigevidon tablets are intended for oral use. They are taken once a day at the same time, without chewing and drinking water. The reception regimen is different in several cases:
- During the previous monthly contraceptive pills were not taken - the drug begins to be used from the first day of the menstrual cycle daily for three weeks. Then you need to take a break of seven days and on the eighth day begins a new blister with medication.
- The beginning of the use of "Rigevidon" after another contraceptive drug - the same dosage regimen and dosage regimen. Application continues as long as there is a need for contraception.
- After an abortion - the use of the medication begins on the day of surgery or the next day after the abortion.
- After childbirth - the drug can be used only for women who are not breastfeeding. The use of tablets begins no earlier than the first day of menstruation.
In their reviews of Rigevidone, women draw attention to the fact that when skipping a pill, it should be taken as soon as possible, provided that no more than twelve hours have passed. If the last dose of the drug was taken for more than thirty-six hours, then the contraceptive effect decreases significantly.
In this situation, missed tablets are not taken, within seven days after the start of the use of the medication, it is necessary to additionally use condoms. The same information is contained in the annotation to the drug. When using "Rigevidon" for pharmacological purposes, the doctor sets the dosage, frequency and regimen of the drug individually.
What to remember
According to the instructions for use and reviews of "Rigevidone", side effects of the drug are rare, but still there are a number of features regarding its use, which are important to pay attention to. These include:
- Before starting to use the drug "Rigevidon", as well as every six months during its use, it is necessary to carry out gynecological and general clinical examination of a woman.
- You can not use the medication for young women with thromboembolic complications.
- The use of the drug is allowed no earlier than six months after receiving antiviral treatment with concomitant viral hepatitis B or C, provided that the laboratory indicators of the functional state of the liver are stabilized.
- The occurrence of sharp pain in the area of localization of the liver when taking the medicine may indicate the possible presence of any neoplasm. In this situation, the use of tablets is canceled until the exclusion of this pathological process.
- The appearance of regular vaginal bleeding that is not associated with the menstrual cycle is not considered an indication for the termination of Rigevidon. In a situation if they are repeated and do not stop, a gynecological examination is necessary.
- Women who smoke from thirty years of age greatly increase the risk of a cardiovascular and cerebrovascular pathological process.
According to the instructions, side effects of "Rigevidon" in certain cases require stopping the medication. The active components of the drug do not directly affect the functional state of the cerebral cortex, the ability to concentrate, and the speed of psychomotor reactions. In the presence of impaired renal function, the drug is used with extreme caution.
The active substances of the drug "Rigevidon" can interact with drugs of other therapeutic groups, therefore, with their simultaneous use, a gynecologist should be warned.
In pharmacies, tablets are dispensed only by prescription from a medical specialist. You can not use them yourself without an appropriate examination and doctor's appointment.
Generics
The following drugs are considered similar in structure and pharmacological action for Rigevidon:
- Lindinet 20
- "Three-regol."
- Klimonorm.
- Triquilar.
- Klaira.
- "Yarina."
- Logest.
- "Regulon."
- "Jeanine."
Before replacing the original drug "Rigevidon" you must consult a medical specialist.
How to store the drug
The shelf life of the medication is sixty months. Rigevidon should be kept in a dry, as well as dark and inaccessible place for children, at room temperature. The cost of the drug varies from 250 to 700 rubles.
Opinions
Most women use oral contraceptives. Therefore, you can find responses about the drug on various Internet resources, where girls are actively discussing such medications.
Opinions on the use of "Rigevidon" in women are mixed. Some believe that oral contraceptives are only beneficial, and actively use them. Others, on the contrary, are afraid to take any birth control pill and therefore use other methods of barrier protection, which are not always effective. In addition, there are responses when patients misuse the drug, and thereby significantly harm their health.
Women who used Rigevidon have very different opinions. Some girls report that during its use they felt nauseous, as well as mood swings and gained weight.
But quite a few women narrate that they have been using Rigevidon for several years, and during that time they did not feel any negative reactions. At the same time, the medication provides them with reliable protection against an unplanned pregnancy.
Medical experts in their reviews of Rigevidon noted that the choice of such birth control pills should not go on their own. If there is a need for contraception, you should contact a doctor at any time to carry out an examination, as well as to determine the hormonal background.